← Back to Search

Cognitive Behavioral Therapy

Cognitive Behavioral Therapy for Chronic Pelvic Pain Syndrome (EPPIC Trial)

N/A
Recruiting
Led By Jeffrey Lackner, PsyD
Research Sponsored by State University of New York at Buffalo
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
All genders, races, ethnic groups
MD-confirmed diagnosis of IC/BPS or CP/CPPS by study urologist or urogynecologist
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline, 12 weeks after pre treatment baseline, 3- and 6-month follow-up
Awards & highlights

EPPIC Trial Summary

This trial is testing a new, short cognitive behavioral therapy for urologic chronic pain syndrome. The hope is that this will be a more practical and effective treatment than existing therapies.

Who is the study for?
The EPPIC study is for adults aged 18-70 with a doctor-confirmed diagnosis of chronic pelvic pain syndromes like interstitial cystitis or chronic prostatitis. Participants must have had pelvic pain for at least six months, be willing to attend therapy sessions, and not start new medications during the initial study period.Check my eligibility
What is being tested?
This trial tests an ultra-brief cognitive behavioral therapy (CBT) designed to treat various urologic chronic pain syndromes. It involves four sessions aimed at easing dissemination and reducing treatment complexity compared to existing therapies.See study design
What are the potential side effects?
Since the interventions involve cognitive behavior therapy and patient education/support, there are no direct medical side effects; however, participants may experience emotional discomfort or increased awareness of their condition during the process.

EPPIC Trial Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
My gender, race, or ethnicity does not limit my participation.
Select...
I have been diagnosed with IC/BPS or CP/CPPS by a specialist.
Select...
I am willing to follow the assigned treatment plan, whether it's CBT or Support/Education.
Select...
I understand the study and can give my consent.
Select...
I am willing to attend all required sessions.
Select...
I am either male or female.
Select...
I am not starting new medications soon or can wait for 2 weeks if needed.
Select...
I have had moderate to severe pelvic pain for the past 3 months that affects my daily life.
Select...
I have had pelvic pain or discomfort for at least six months.
Select...
I agree to follow-up checks at week 12 and 3, 6 months after my treatment.
Select...
I am between 18 and 70 years old.

EPPIC Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~12 weeks after pre-treatment baseline
This trial's timeline: 3 weeks for screening, Varies for treatment, and 12 weeks after pre-treatment baseline for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Clinical Global Impressions - Improvement Scale Patient Version (CGI-I)
Secondary outcome measures
Brief Symptom Inventory (BSI 18)
Client Satisfaction Questionnaire (CSQ)
Genitourinary Pain Index (GUPI)
+3 more
Other outcome measures
Beck Depression Inventory - II (BDI-II)
Change from baseline of the PROMIS - Sleep Disturbance SF-8b
PROMIS - Fatigue SF-7a
+3 more

EPPIC Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Minimal Contact-Cognitive Behavior TherapyExperimental Treatment1 Intervention
CBT is a goal-focused, learning-based treatment that teaches practical self-management tools and strategies targeting biobehavioral factors that aggravate pelvic pain and urinary symptoms
Group II: Education/SupportActive Control1 Intervention
EDU emphasizes the empowering therapeutic benefits that come from the common across empirically-validated drug or non-drug treatment such as being listened to, support, receipt of science-based information, mobilization of hope, and the establishment of a strong patient-doctor relationship working toward shared goals

Find a Location

Who is running the clinical trial?

State University of New York at BuffaloLead Sponsor
245 Previous Clinical Trials
49,228 Total Patients Enrolled
University of MichiganOTHER
1,786 Previous Clinical Trials
6,364,882 Total Patients Enrolled
University of California, Los AngelesOTHER
1,525 Previous Clinical Trials
10,279,194 Total Patients Enrolled

Media Library

Chronic Pelvic Pain Syndrome Research Study Groups: Minimal Contact-Cognitive Behavior Therapy, Education/Support

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Does the experiment encompass individuals aged 75 and above?

"This clinical trial has a stipulated age range for participants, which is 18 years of age or above up to 70."

Answered by AI

What is the maximum enrolment capacity for this research program?

"Affirmative. The information on clinicaltrials.gov reveals that this experiment is presently looking for participants, which was initially published on August 10th 2022 and most recently revised on the 22nd of August. Altogether, 240 subjects need to be enrolled from 2 distinct trial sites."

Answered by AI

Is there any possibility of my involvement in this clinical trial?

"The prerequisites for acceptance into this clinical trial are chronic pain and an age range between 18 to 70 years old. The research team is attempting to recruit approximately 240 individuals."

Answered by AI

Are any additional participants being welcomed into this trial?

"Affirmative. The information on clinicaltrials.gov suggests that, as of August 22nd 2022, this trial is still seeking individuals to take part in it. Originally posted on the 10th of August 20202, the study hopes to recruit a total 240 patients from 2 locations."

Answered by AI

Who else is applying?

What state do they live in?
California
How old are they?
18 - 65
What site did they apply to?
UCLA
What portion of applicants met pre-screening criteria?
Met criteria

How responsive is this trial?

Typically responds via
Email
Recent research and studies
~123 spots leftby Nov 2025