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What is Fetzima
LevomilnacipranThe Generic name of this drug
Treatment SummaryLevomilnacipran is a medication that helps regulate levels of serotonin and norepinephrine in the brain. It is the mirror opposite of the drug milnacipran and was approved by the FDA in 2013. It is used to treat depression and other mental health conditions.
Fetzimais the brand name
Fetzima Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Fetzima
Levomilnacipran
2013
10
Approved as Treatment by the FDA
Levomilnacipran, also known as Fetzima, is approved by the FDA for 1 uses including Depression .Depression
Effectiveness
How Fetzima Affects PatientsLevomilnacipran binds tightly to both serotonin and norepinephrine in the body and prevents them from being reabsorbed naturally. It does not interact with many other receptors, ion channels, transporters, or enzymes, and does not cause a significant increase in the QTc interval.
How Fetzima works in the bodyThe way levomilnacipran works as an antidepressant is unknown, but it is believed to help by increasing the levels of serotonin and norepinephrine in the brain by blocking how they are reabsorbed.
When to interrupt dosage
The proposed measure of Fetzima is contingent upon the ascertained health problem. The quantity of dosage varies, as indicated by the administration technique (e.g. Kit or Oral) shown in the table beneath.Condition
Dosage
Administration
Depression
, 40.0 mg, 120.0 mg, 20.0 mg, 80.0 mg
, Oral, Capsule, extended release, Capsule, extended release - Oral, Kit, Kit - Oral
Warnings
Fetzima ContraindicationsCondition
Risk Level
Notes
Pulse Frequency
Do Not Combine
Common Fetzima Drug Interactions
Drug Name
Risk Level
Description
Acetyldigoxin
Major
The risk or severity of hypotension can be increased when Levomilnacipran is combined with Acetyldigoxin.
Amitriptyline
Major
The metabolism of Amitriptyline can be decreased when combined with Levomilnacipran.
Amoxapine
Major
The metabolism of Amoxapine can be decreased when combined with Levomilnacipran.
Astemizole
Major
The metabolism of Astemizole can be decreased when combined with Levomilnacipran.
Azelastine
Major
Levomilnacipran may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Fetzima Toxicity & Overdose RiskCommon side effects of overdose on this drug include nausea, constipation, excessive sweating, increased heart rate, sexual dysfunction, rapid heartbeat, vomiting, and feeling heartbeats in the chest.
Fetzima Novel Uses: Which Conditions Have a Clinical Trial Featuring Fetzima?
186 active clinical trials are exploring the potential of Fetzima in treating Depressive Symptoms.Condition
Clinical Trials
Trial Phases
Depression
198 Actively Recruiting
Phase 2, Phase 3, Not Applicable, Phase 1, Phase 4, Early Phase 1
Fetzima Reviews: What are patients saying about Fetzima?
5Patient Review
9/27/2016 This medication has helped me with my depression. I have more energy and focus, and my mood is improved. I'm able to sleep just fine on this medication. No negative side effects so far.
5Patient Review
4/4/2019 I've tried nearly every antidepressant out there to treat my MDD, and none of them have really done the trick—until now. My doctor prescribed Fetzima for me to use in conjunction with Wellbutrin, and I honestly couldn't be happier. These drugs, along with regular visits to a therapist, saved my life. I've been taking them steadily for 3-4 years now and feel great. The only side effect I've noticed is dry mouth. All things considered, I'm very pleased with this medication and hope a generic version comes soon.
4.7Patient Review
10/3/2019 In addition to the other medications I take for depression/bipolarity, this has helped me by increasing my energy levels. I'm currently taking 40 mg, but I'm curious to see if a higher dosage would have even more of an impact.
2Patient Review
8/20/2016 I'm on 120mg and I've been experiencing more stomach pain, anxiety, and general malaise. I haven't been able to leave my bed much and have lost my appetite.
1.7Patient Review
6/9/2022 Fetzima had some benefits at first, but the side effects became unbearable. My heart rate was constantly high and I was sweating all day long. It also seemed to worsen my mood after a while, so I'm slowly weaning myself off of it.
1Patient Review
8/12/2016 After taking this for a month, I only saw minimal improvement. In the year that I took it, I never felt any relief from anxiety, an ability to multi-task or ease in completing projects. If anything, my sleep got worse.
1Patient Review
8/3/2016 This drug increased my anxiety to the point where I was having panic attacks, crying, shaking, and feeling hopeless. It also caused chest pain and decreased appetite.
Patient Q&A Section about fetzima
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.Is Fetzima good for anxiety?
"Fetzima is a drug that is used to treat generalized anxiety disorder. This drug is recommended as a first-choice treatment option by the Anxiety and Depression Association of America."
Answered by AI
What is Fetzima prescribed for?
"The prescription medication FETZIMA is used to treat Major Depressive Disorder in adults. It is not meant to be used for the management of fibromyalgia and its effectiveness and safety have not been determined for that use."
Answered by AI
Is Fetzima a good antidepressant?
"More than 1700 adults with depression took part in clinical studies that evaluated FETZIMA. The studies lasted for 8 weeks and the participants taking FETZIMA had significant improvement in their overall depressive symptoms and their ability to function in their everyday lives."
Answered by AI
What are the side effects of Fetzima?
"The most common side effects for patients taking FETZIMA include nausea and vomiting, constipation, sweating, increased heart rate, erectile dysfunction and palpitations. If you experience any of these side effects, tell your healthcare provider."
Answered by AI