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What is Effient
PrasugrelThe Generic name of this drug
Treatment SummaryPrasugrel is a medication used to reduce the risk of heart attack and stroke by preventing platelet activation and aggregation. It works by binding to a certain type of ADP receptor on platelets, which in turn inhibits the GPIIb/IIIa receptor complex and prevents platelets from sticking together. Prasugrel was developed by Daiichi Sankyo Co. and FDA approved in 2009, and it is currently marketed in the United States and Canada in cooperation with Eli Lilly and Company for acute coronary syndromes planned for percutaneous coronary intervention (PCI).
Effientis the brand name
Effient Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Effient
Prasugrel
2009
37
Approved as Treatment by the FDA
Prasugrel, otherwise called Effient, is approved by the FDA for 6 uses including Percutaneous coronary intervention, Unstable angina and Percutaneous Coronary Intervention .Percutaneous coronary intervention, Unstable angina
Percutaneous Coronary Intervention
prophylaxis of cardiovascular event
Angina, Unstable
Cardiovascular Events
Percutaneous Coronary Intervention
Effectiveness
How Effient Affects PatientsPrasugrel is a type of medicine that stops platelets from clumping together and forming clots. It does this by attaching to a specific receptor (P2Y12) in the body and blocking it. The effect is irreversible.
How Effient works in the bodyPrasugrel is a drug that stops platelets in your blood from sticking together, which prevents blood clots. It does this by blocking a receptor on platelets called P2Y12. Prasugrel works similarly to another drug, clopidogrel.
When to interrupt dosage
The proposed dosage of Effient is determined by the diagnosed affliction, including Percutaneous Coronary Intervention, Angina, Unstable and prophylaxis of cardiovascular event. The measure of dosage fluctuates, depending on the technique of delivery (e.g. Tablet, film coated - Oral or Tablet, coated - Oral) as indicated in the table below.Condition
Dosage
Administration
Angina, Unstable
, 10.0 mg, 5.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Tablet, coated, Tablet, coated - Oral
Percutaneous Coronary Intervention
, 10.0 mg, 5.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Tablet, coated, Tablet, coated - Oral
Percutaneous Coronary Intervention
, 10.0 mg, 5.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Tablet, coated, Tablet, coated - Oral
prophylaxis of cardiovascular event
, 10.0 mg, 5.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Tablet, coated, Tablet, coated - Oral
Cardiovascular Events
, 10.0 mg, 5.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Tablet, coated, Tablet, coated - Oral
Warnings
Effient ContraindicationsCondition
Risk Level
Notes
Ischemic Attack, Transient
Do Not Combine
Hemorrhage
Do Not Combine
Stroke
Do Not Combine
Common Effient Drug Interactions
Drug Name
Risk Level
Description
Abrocitinib
Major
The risk or severity of bleeding and thrombocytopenia can be increased when Prasugrel is combined with Abrocitinib.
Albutrepenonacog alfa
Major
The therapeutic efficacy of Albutrepenonacog alfa can be decreased when used in combination with Prasugrel.
Andexanet alfa
Major
The therapeutic efficacy of Andexanet alfa can be decreased when used in combination with Prasugrel.
Anti-inhibitor coagulant complex
Major
The therapeutic efficacy of Anti-inhibitor coagulant complex can be decreased when used in combination with Prasugrel.
Antihemophilic factor (recombinant), PEGylated
Major
The therapeutic efficacy of Antihemophilic factor (recombinant), PEGylated can be decreased when used in combination with Prasugrel.
Effient Toxicity & Overdose RiskThe level of toxicity for this drug is high, with the lethal dose for rats being between 1,000 to 2,000 mg/kg and the lethal dose for rabbits being greater than 1,000 mg/kg.
Effient Novel Uses: Which Conditions Have a Clinical Trial Featuring Effient?
Three active clinical trials are currently evaluating the potential of Effient for Percutaneous Coronary Intervention, Percutaneous Coronary Intervention and Unstable Angina.Condition
Clinical Trials
Trial Phases
Percutaneous Coronary Intervention
0 Actively Recruiting
Cardiovascular Events
4 Actively Recruiting
Not Applicable
Angina, Unstable
0 Actively Recruiting
prophylaxis of cardiovascular event
0 Actively Recruiting
Percutaneous Coronary Intervention
0 Actively Recruiting
Effient Reviews: What are patients saying about Effient?
5Patient Review
12/18/2015 The only issue I had was that I couldn't take Metformin.
5Patient Review
8/5/2015 After my stent procedure in 2011, my cardiologist put me on Effient. I had no side effects whatsoever!
5Patient Review
9/18/2014 I started using this drug immediately after I had a stint installed in my heart. No side effects.
4.7Patient Review
5/29/2017 I haven't experienced any negative effects from this medication, other than the bruises that show up when I accidentally hit my arms or hands. The price is a bit high, but luckily my doctor sometimes has samples on hand.
4.3Patient Review
7/12/2014 This medication is effective, but I'm keeping an eye out for any potential food interactions. So far, no problems while drinking green juice regularly.
Patient Q&A Section about effient
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.Is Plavix and Effient the same?
"Plavix becomes an active drug after undergoing two chemical reactions. Dr. Sep 17, 2009 stated that Effient is more beneficial than Plavix because it is more efficient in preventing platelets from stick together."
Answered by AI
What is Effient used for?
"This medication helps prevent other serious heart and blood vessel problems, such as heart attacks, strokes, and blood clots in stents, by blocking platelets from sticking together and forming harmful blood clots."
Answered by AI
What kind of drug is Effient?
"Effient is an antiplatelet drug designed to prevent the formation of blood clots, which can lead to heart attacks."
Answered by AI
Is Effient and eliquis the same?
"Effient and Eliquis are both drugs that have side effects that include increased bleeding, nausea, and skin rash."
Answered by AI
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