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What is Detrol La
TolterodineThe Generic name of this drug
Treatment SummaryTolterodine is a medication used to treat urinary incontinence. It targets specific types of muscle cells in the bladder and helps to reduce the symptoms of incontinence.
Detrolis the brand name
Detrol La Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Detrol
Tolterodine
1998
78
Effectiveness
How Detrol La Affects PatientsTolterodine is a medicine that blocks certain receptors in the body (muscarinic receptors) to help reduce symptoms of an overactive bladder. After taken orally, the drug is processed in the liver and become a metabolite responsible for the drug's effects. This metabolite specifically targets muscarinic receptors, not other receptors like calcium channels, and helps the body relax the bladder and reduce pressure. The effects of tolterodine on bladder function include increasing urine that is left in the bladder and reducing pressure.
How Detrol La works in the bodyTolterodine reduces the activity of muscles in your bladder, reducing the pressure in the bladder and improving bladder emptying. It works by blocking the effects of a neurotransmitter that would normally make the bladder muscles contract.
When to interrupt dosage
The quantity of Detrol La is contingent upon the diagnosed affliction. The amount of dosage differs, in accordance with the method of delivery (e.g. Capsule, extended release - Oral or Tablet - Oral) specified in the following table.Condition
Dosage
Administration
Urinary Urge Incontinence
1.0 mg, , 2.0 mg, 4.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Tablet, extended release, Tablet, extended release - Oral
Overactive Bladder Syndrome
1.0 mg, , 2.0 mg, 4.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Tablet, extended release, Tablet, extended release - Oral
Warnings
Detrol La has three contraindications, and use of it should be avoided when suffering from any of the conditions provided in the following table.Detrol La ContraindicationsCondition
Risk Level
Notes
Urinary Retention
Do Not Combine
uncontrolled narrow-angle glaucoma
Do Not Combine
Gastric Retention
Do Not Combine
Common Detrol La Drug Interactions
Drug Name
Risk Level
Description
Aclidinium
Major
The risk or severity of adverse effects can be increased when Tolterodine is combined with Aclidinium.
Amitriptyline
Major
The metabolism of Amitriptyline can be decreased when combined with Tolterodine.
Amoxapine
Major
The metabolism of Amoxapine can be decreased when combined with Tolterodine.
Astemizole
Major
The metabolism of Astemizole can be decreased when combined with Tolterodine.
Cimetropium
Major
The risk or severity of adverse effects can be increased when Tolterodine is combined with Cimetropium.
Detrol La Novel Uses: Which Conditions Have a Clinical Trial Featuring Detrol La?
42 active studies are being conducted to investigate the potential of Detrol La in providing relief from Overactive Bladder Syndrome.Condition
Clinical Trials
Trial Phases
Urinary Urge Incontinence
15 Actively Recruiting
Not Applicable, Phase 4, Phase 2
Overactive Bladder Syndrome
32 Actively Recruiting
Not Applicable, Phase 3, Phase 4, Phase 1, Phase 2
Detrol La Reviews: What are patients saying about Detrol La?
5Patient Review
8/10/2016 This medication was extremely effective for me and helped clear up my condition quickly. The only downside is that it caused me to have a very dry mouth.
5Patient Review
8/10/2016 This medication was really effective for me and helped a lot. The only downside is that it gives me a very dry mouth.
4.7Patient Review
9/17/2015 This treatment has helped me a lot with my overactive bladder.
4.7Patient Review
9/26/2013 This didn't fully solve my problem, but it did help somewhat. I'm still leaking and wetting a diaper in the morning, but some of my symptoms have improved.
4.7Patient Review
6/24/2013 I haven't seen any results yet, but I'm still hopeful.
4.7Patient Review
9/26/2013 While this medication didn't completely solve my problem, it did help to alleviate some of the symptoms.
4.7Patient Review
6/24/2013 I'm still waiting to see results from this treatment, but I remain hopeful.
4.7Patient Review
9/17/2015 This treatment has been extremely effective in managing my overactive bladder. It's allowed me to live a much more normal life without having to worry about accidents.
4.3Patient Review
10/23/2013 I felt pretty tired while taking this medication, and occasionally experienced dizzy spells. That said, it was still effective for me.
4.3Patient Review
10/23/2013 I have felt tired and dizzy while taking this medication. It unfortunately has not been effective for me.
4Patient Review
11/23/20124Patient Review
11/23/20123.7Patient Review
5/25/2013 I found the effects of this medication to be quite unpredictable.
3.7Patient Review
5/25/2013 I found the effects of this treatment to be very unpredictable.
2.7Patient Review
6/17/2016 After learning about the potential side effects of this drug, I stopped taking it. The most worrisome possible side effect is how it affects the brain, especially relating to dementia. For the little help I noticed, it's definitely not worth the risk to me.
2.7Patient Review
5/27/2014 I experienced a lot of irritation and felt like I had a UTI while taking this medication. Cranberry tablets helped somewhat, but the symptoms were still worse than they were before I started taking the medication.
2.7Patient Review
12/16/2014 My doctor started me on Detrol La a few months ago for a kidney stone that hasn't moved in years. Recently, I've been experiencing more pain in the area around my right kidney. Could this be from the medication? The pain is even sensitive to touch now and it's getting tough to manage. So far urination isn't an issue though.
2.7Patient Review
12/16/2014 I have a kidney stone that's been stuck for over six years now. My doctor put me on Detrol about two months ago, and since then I've been having sporadic but really painful episodes in the same area. Even just touching lightly causes pain now. There haven't been any changes to my urination though.
2.7Patient Review
5/27/2014 I developed irritation and other urinary tract symptoms after starting this medication. Thankfully, cranberry tablets have helped to alleviate these issues somewhat. However, I find that the symptoms are worse when I first wake up in the morning. Overall, I feel like my condition has worsened since taking this drug.
2.7Patient Review
6/17/2016 After learning more about the potential risks, I have stopped taking Detrol LA. The most worrisome possible side effect is how it affects the brain, especially relating to dementia. For the little help I noticed, it's definitely not worth the risk to me.
2.3Patient Review
6/3/2013 I only have the urge to urinate when I'm bouncing around, and Detrol helps way more than the cheaper stuff. Although, the more I use it, the more hair I seem to be losing. Idk if it's the meds, but the drying effects of Detrol has me concerned that it could be making hair loss increase much more rapidly.
2.3Patient Review
3/19/2014 An effective medication, but it's so expensive which is tough because I'm on a fixed income.
2.3Patient Review
3/19/2014 An effective medication that I've been taking for a while now. The biggest downside is the cost; as a senior citizen on a fixed income, it's tough to keep up with.
2.3Patient Review
6/3/2013 I find that Detrol helps me to urinate less frequently than other, cheaper medications; however, I have noticed that the more I use it, the more hair I seem to lose. I'm not sure if this is a side effect of the medication or not, but it is something that concerns me.
2Patient Review
9/24/20122Patient Review
9/24/20121Patient Review
9/24/2013 I had been having daytime accidents when I couldn't get to the restroom on time. Detrol has worked great for me. Now, suddenly, my copay per month went from $30 to $85 so I will have to find something else as I cannot afford this.
1Patient Review
3/26/2014 I had a very severe reaction to Detrol LA and it nearly gave me a stroke.
1Patient Review
9/24/2013 I was having a lot of issues with incontinence, but this drug really helped me. However, the price per month went from $30 to $85 and I just can't afford that.
1Patient Review
3/26/2014 Do not take this medication if you value your health. I nearly had a stroke as a result of taking just one Detrol LA pill.
Patient Q&A Section about detrol la
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What is the generic name for Detrol LA?
"Tolterodine may also be used for purposes not listed in this medication guide.
Tolterodine is a medication used to treat overactive bladder with symptoms like urge urinary incontinence, urgency, and frequency. It is available under the brand names Detrol and Detrol LA. Tolterodine may also be used for other purposes not listed in this guide."
Answered by AI
What are the side effects of Detrol LA?
"Tell your doctor if any of the following side effects last or get worse: dry mouth, dry eyes, headache, constipation, stomach upset/pain, dizziness, drowsiness, or tiredness."
Answered by AI
Should I take Detrol in the morning or at night?
"For adults, the recommended dosage of tolterodine is 2mg in the morning and 2mg in the evening, with a 12 hour gap in between doses. For children, the usual dosage is 1-4mg per day, depending on the child's age and weight. If you are giving tolterodine to a child to stop bedwetting, the usual dose is 1mg taken at bedtime."
Answered by AI
How long does it take Detrol LA to work?
"Questions that are frequently asked about tolterodine (Detrol) include how soon the medication can start working and how long it might take to feel the full effects. It is important to continue taking the medication every day, even if there is no improvement in symptoms of OAB, to give the medication time to work to its full potential."
Answered by AI