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What is Detrol La
TolterodineThe Generic name of this drug
Treatment SummaryTolterodine is a medication used to treat urinary incontinence. It targets specific types of muscle cells in the bladder and helps to reduce the symptoms of incontinence.
Detrolis the brand name
Detrol La Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Detrol
Tolterodine
1998
78
Effectiveness
How Detrol La Affects PatientsTolterodine is a medicine that blocks certain receptors in the body (muscarinic receptors) to help reduce symptoms of an overactive bladder. After taken orally, the drug is processed in the liver and become a metabolite responsible for the drug's effects. This metabolite specifically targets muscarinic receptors, not other receptors like calcium channels, and helps the body relax the bladder and reduce pressure. The effects of tolterodine on bladder function include increasing urine that is left in the bladder and reducing pressure.
How Detrol La works in the bodyTolterodine reduces the activity of muscles in your bladder, reducing the pressure in the bladder and improving bladder emptying. It works by blocking the effects of a neurotransmitter that would normally make the bladder muscles contract.
When to interrupt dosage
The quantity of Detrol La is contingent upon the diagnosed affliction. The amount of dosage differs, in accordance with the method of delivery (e.g. Capsule, extended release - Oral or Tablet - Oral) specified in the following table.Condition
Dosage
Administration
Overactive Bladder Syndrome
1.0 mg, , 2.0 mg, 4.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Tablet, extended release, Tablet, extended release - Oral
Urinary Incontinence, Urge
1.0 mg, , 2.0 mg, 4.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Tablet, extended release, Tablet, extended release - Oral
Warnings
Detrol La has three contraindications, and use of it should be avoided when suffering from any of the conditions provided in the following table.Detrol La ContraindicationsCondition
Risk Level
Notes
Urinary Retention
Do Not Combine
uncontrolled narrow-angle glaucoma
Do Not Combine
Gastric Retention
Do Not Combine
Common Detrol La Drug Interactions
Drug Name
Risk Level
Description
Aclidinium
Major
The risk or severity of adverse effects can be increased when Tolterodine is combined with Aclidinium.
Amitriptyline
Major
The metabolism of Amitriptyline can be decreased when combined with Tolterodine.
Amoxapine
Major
The metabolism of Amoxapine can be decreased when combined with Tolterodine.
Astemizole
Major
The metabolism of Astemizole can be decreased when combined with Tolterodine.
Cimetropium
Major
The risk or severity of adverse effects can be increased when Tolterodine is combined with Cimetropium.
Detrol La Novel Uses: Which Conditions Have a Clinical Trial Featuring Detrol La?
42 active studies are being conducted to investigate the potential of Detrol La in providing relief from Overactive Bladder Syndrome.Condition
Clinical Trials
Trial Phases
Urinary Incontinence, Urge
17 Actively Recruiting
Not Applicable, Phase 4, Phase 2
Overactive Bladder Syndrome
36 Actively Recruiting
Not Applicable, Phase 3, Phase 4, Phase 1, Phase 2
Detrol La Reviews: What are patients saying about Detrol La?
5Patient Review
8/10/2016 This medication was extremely effective for me and helped clear up my condition quickly. The only downside is that it caused me to have a very dry mouth.
5Patient Review
8/10/2016 This medication was really effective for me and helped a lot. The only downside is that it gives me a very dry mouth.
4.7Patient Review
9/17/2015 This treatment has helped me a lot with my overactive bladder.
4.7Patient Review
9/26/2013 This didn't fully solve my problem, but it did help somewhat. I'm still leaking and wetting a diaper in the morning, but some of my symptoms have improved.
4.7Patient Review
6/24/2013 I haven't seen any results yet, but I'm still hopeful.
Patient Q&A Section about detrol la
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What is the generic name for Detrol LA?
"Tolterodine may also be used for purposes not listed in this medication guide.
Tolterodine is a medication used to treat overactive bladder with symptoms like urge urinary incontinence, urgency, and frequency. It is available under the brand names Detrol and Detrol LA. Tolterodine may also be used for other purposes not listed in this guide."
Answered by AI
What are the side effects of Detrol LA?
"Tell your doctor if any of the following side effects last or get worse: dry mouth, dry eyes, headache, constipation, stomach upset/pain, dizziness, drowsiness, or tiredness."
Answered by AI
Should I take Detrol in the morning or at night?
"For adults, the recommended dosage of tolterodine is 2mg in the morning and 2mg in the evening, with a 12 hour gap in between doses. For children, the usual dosage is 1-4mg per day, depending on the child's age and weight. If you are giving tolterodine to a child to stop bedwetting, the usual dose is 1mg taken at bedtime."
Answered by AI
How long does it take Detrol LA to work?
"Questions that are frequently asked about tolterodine (Detrol) include how soon the medication can start working and how long it might take to feel the full effects. It is important to continue taking the medication every day, even if there is no improvement in symptoms of OAB, to give the medication time to work to its full potential."
Answered by AI
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