Cyklokapron

Hyperfibrinolysis, Hemorrhage, Angioedemas, Hereditary + 3 more
Treatment
16 Active Studies for Cyklokapron

What is Cyklokapron

Tranexamic acidThe Generic name of this drug
Treatment SummaryTranexamic acid is a medication that helps to reduce bleeding. It is a synthetic form of lysine, and is more effective than other similar drugs. It was first patented in 1957 and approved for use in the United States in 1986.
Cyklokapronis the brand name
Cyklokapron Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Cyklokapron
Tranexamic acid
1986
57

Effectiveness

How Cyklokapron Affects PatientsTranexamic acid is a medication used to reduce bleeding. It works by stopping the breakdown of blood clots, which helps to stop bleeding. It is used to treat hereditary angioedema, a condition that causes swelling. In some cases, tranexamic acid can cause convulsions or increased excitability in patients. Therefore, those with a history of seizures should have their EEG monitored when taking this drug.
How Cyklokapron works in the bodyTranexamic acid works by stopping the breakdown of blood clots. It does this by attaching to the same sites on blood clots that would normally cause them to dissolve. By occupying these sites, it prevents the clot from breaking down and stops bleeding.

When to interrupt dosage

The advised dosage of Cyklokapron is contingent upon the diagnosed condition, including Tooth Extractions, Angioedemas, Hereditary and Hemophilia. The amount also deviates as per the mode of delivery (e.g. Cream - Topical or Injection, solution - Intravenous) outlined in the table beneath.
Condition
Dosage
Administration
Hyperfibrinolysis
100.0 mg/mL, , 650.0 mg, 0.005 mg/mL, 500.0 mg, 2.0 mg/mL, 5.0 mg/mL, 0.1 mg/mL, 10.0 mg/mL, 500.0 mg/mL
, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, Tablet - Oral, Oral, Tablet, film coated, Tablet, film coated - Oral, Topical, Cream, Cream - Topical, Solution, Solution - Intravenous, Injection, Injection - Intravenous, Liquid, Liquid - Topical
Hemorrhage
100.0 mg/mL, , 650.0 mg, 0.005 mg/mL, 500.0 mg, 2.0 mg/mL, 5.0 mg/mL, 0.1 mg/mL, 10.0 mg/mL, 500.0 mg/mL
, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, Tablet - Oral, Oral, Tablet, film coated, Tablet, film coated - Oral, Topical, Cream, Cream - Topical, Solution, Solution - Intravenous, Injection, Injection - Intravenous, Liquid, Liquid - Topical
Angioedemas, Hereditary
100.0 mg/mL, , 650.0 mg, 0.005 mg/mL, 500.0 mg, 2.0 mg/mL, 5.0 mg/mL, 0.1 mg/mL, 10.0 mg/mL, 500.0 mg/mL
, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, Tablet - Oral, Oral, Tablet, film coated, Tablet, film coated - Oral, Topical, Cream, Cream - Topical, Solution, Solution - Intravenous, Injection, Injection - Intravenous, Liquid, Liquid - Topical
Hemophilia A
100.0 mg/mL, , 650.0 mg, 0.005 mg/mL, 500.0 mg, 2.0 mg/mL, 5.0 mg/mL, 0.1 mg/mL, 10.0 mg/mL, 500.0 mg/mL
, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, Tablet - Oral, Oral, Tablet, film coated, Tablet, film coated - Oral, Topical, Cream, Cream - Topical, Solution, Solution - Intravenous, Injection, Injection - Intravenous, Liquid, Liquid - Topical
Menorrhagia
100.0 mg/mL, , 650.0 mg, 0.005 mg/mL, 500.0 mg, 2.0 mg/mL, 5.0 mg/mL, 0.1 mg/mL, 10.0 mg/mL, 500.0 mg/mL
, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, Tablet - Oral, Oral, Tablet, film coated, Tablet, film coated - Oral, Topical, Cream, Cream - Topical, Solution, Solution - Intravenous, Injection, Injection - Intravenous, Liquid, Liquid - Topical
Tooth Extractions
100.0 mg/mL, , 650.0 mg, 0.005 mg/mL, 500.0 mg, 2.0 mg/mL, 5.0 mg/mL, 0.1 mg/mL, 10.0 mg/mL, 500.0 mg/mL
, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, Tablet - Oral, Oral, Tablet, film coated, Tablet, film coated - Oral, Topical, Cream, Cream - Topical, Solution, Solution - Intravenous, Injection, Injection - Intravenous, Liquid, Liquid - Topical

Warnings

Cyklokapron Contraindications
Condition
Risk Level
Notes
Severe Hypersensitivity Reactions
Do Not Combine
Tranexamic Acid may interact with Pulse Frequency
NF1 gene
Do Not Combine
Thrombosis
Do Not Combine
Thromboembolism
Do Not Combine
Pulse Frequency
Do Not Combine
Subarachnoid Hemorrhage
Do Not Combine
There are 20 known major drug interactions with Cyklokapron.
Common Cyklokapron Drug Interactions
Drug Name
Risk Level
Description
Albutrepenonacog alfa
Major
Tranexamic acid may increase the thrombogenic activities of Albutrepenonacog alfa.
Aminocaproic acid
Major
Tranexamic acid may increase the thrombogenic activities of Aminocaproic acid.
Aminomethylbenzoic acid
Major
Tranexamic acid may increase the thrombogenic activities of Aminomethylbenzoic acid.
Andexanet alfa
Major
Tranexamic acid may increase the thrombogenic activities of Andexanet alfa.
Anti-inhibitor coagulant complex
Major
Tranexamic acid may increase the thrombogenic activities of Anti-inhibitor coagulant complex.
Cyklokapron Toxicity & Overdose RiskToo much tranexamic acid can cause severe stomach issues, low blood pressure, blood clots, vision problems, seizures, changes in mental state, and skin rashes.

Cyklokapron Novel Uses: Which Conditions Have a Clinical Trial Featuring Cyklokapron?

34 active trials are in progress to assess the potential of Cyklokapron in managing Hemophilia, Hemorrhage and Hereditary Angioedemas.
Condition
Clinical Trials
Trial Phases
Hemorrhage
0 Actively Recruiting
Hyperfibrinolysis
0 Actively Recruiting
Tooth Extractions
3 Actively Recruiting
Not Applicable, Early Phase 1
Angioedemas, Hereditary
13 Actively Recruiting
Phase 3, Phase 2, Phase 1, Phase 4
Menorrhagia
0 Actively Recruiting
Hemophilia A
0 Actively Recruiting

Cyklokapron Reviews: What are patients saying about Cyklokapron?

5Patient Review
10/4/2019
Cyklokapron for Abnormally Long or Heavy Periods
This treatment completely changed my life for the better. I used to have heavy cycles that would last for years, and it became so bad that I was anemic and had to sleep with pads on my bed. But since using this treatment, I haven't had any issues at all! My period has become shorter and lighter, and I couldn't be happier.
5Patient Review
7/9/2022
Cyklokapron for Abnormally Long or Heavy Periods
I've been really impressed with this treatment. I was experiencing heavy flows for two years straight and nothing seemed to help. But this has definitely made a difference.
5Patient Review
5/18/2022
Cyklokapron for Abnormally Long or Heavy Periods
So, I've only been taking this for a month. But as a 45-year-old woman who has always had really heavy and painful periods, let me say: 650mg three times per day during my period for three days has resulted in a significant decrease of bleeding and clots. The only adverse effect I noticed was some minor headaches.
5Patient Review
9/27/2021
Cyklokapron for Abnormally Long or Heavy Periods
I have fibroids and my periods cause my anemia. So far I have seen a decrease in the amount of time I have had my periods since taking this medication, as well as the menstrual pain and swelling that occurs.
5Patient Review
5/18/2022
Cyklokapron for Abnormally Long or Heavy Periods
I tried this medication for the first time last month and it was incredibly effective. I'm a 45-year-old woman who has always had heavy, painful periods. This medication helped to reduce both the bleeding and clotting within the first day of my period. The only adverse effect I experienced was minor headaches.
View All Reviews
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Patient Q&A Section about cyklokapron

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What type of medication is CYKLOKAPRON?

"Cyklokapron is a man-made form of lysine, an amino acid, used to prevent bleeding in people with hemophilia who need dental procedures. Cyklokapron is typically given just before the dental procedure and daily for up to eight days afterward."

Answered by AI

How long does it take for CYKLOKAPRON to work?

"The medicine will not have its full effect for up to 24 hours. Tranexamic acid is typically only used for a short time to treat bleeding. For heavy periods, it is usually taken for four days, or for seven days to treat other types of bleeding that does not stop on its own."

Answered by AI

Is CYKLOKAPRON a blood thinner?

"Tranexamic acid reduces the amount of blood loss and is used to control unwanted bleeding. Side-effects are usually minor and rare."

Answered by AI

What is CYKLOKAPRON used for?

"This medication is used to prevent and reduce bleeding from a tooth extraction in people with hemophilia, a bleeding disorder."

Answered by AI

Clinical Trials for Cyklokapron

Have you considered Cyklokapron clinical trials? We made a collection of clinical trials featuring Cyklokapron, we think they might fit your search criteria.
Have you considered Cyklokapron clinical trials? We made a collection of clinical trials featuring Cyklokapron, we think they might fit your search criteria.
Have you considered Cyklokapron clinical trials? We made a collection of clinical trials featuring Cyklokapron, we think they might fit your search criteria.
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