Crixivan

HIV
Treatment
1 FDA approval
20 Active Studies for Crixivan

What is Crixivan

IndinavirThe Generic name of this drug
Treatment SummaryA powerful medication to treat HIV infection that can be taken orally and is quickly absorbed into the body.
Crixivanis the brand name
image of different drug pills on a surface
Crixivan Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Crixivan
Indinavir
1996
8

Approved as Treatment by the FDA

Indinavir, otherwise called Crixivan, is approved by the FDA for 1 uses including HIV .
HIV
Used to treat Human Immunodeficiency Virus Type 1 (HIV-1) Infection in combination with null

Effectiveness

How Crixivan Affects PatientsIndinavir is a medication used to treat HIV-1. It works by blocking a part of HIV called protease, which is an enzyme HIV needs to survive. By preventing the enzyme from working properly, Indinavir stops HIV from forming into infectious particles. It is usually used in combination with other anti-HIV drugs to make sure the virus is completely stopped.
How Crixivan works in the bodyIndinavir stops HIV from maturing by blocking an enzyme that helps it form into a complete virus. Without this enzyme, HIV cannot form into a mature virus and cannot spread.

When to interrupt dosage

The recommended dosage of Crixivan is contingent upon the diagnosed situation. The amount of dosage fluctuates, according to the method of administration (e.g. Capsule or Oral) specified in the table below.
Condition
Dosage
Administration
HIV
, 400.0 mg, 200.0 mg, 300.0 mg, 100.0 mg, 333.0 mg
, Oral, Capsule, Capsule - Oral

Warnings

Crixivan Contraindications
Condition
Risk Level
Notes
Pulse Frequency
Do Not Combine
There are 20 known major drug interactions with Crixivan.
Common Crixivan Drug Interactions
Drug Name
Risk Level
Description
(R)-warfarin
Major
The metabolism of (R)-warfarin can be decreased when combined with Indinavir.
(S)-Warfarin
Major
The metabolism of (S)-Warfarin can be decreased when combined with Indinavir.
1,2-Benzodiazepine
Major
The metabolism of 1,2-Benzodiazepine can be decreased when combined with Indinavir.
3,5-diiodothyropropionic acid
Major
The metabolism of 3,5-diiodothyropropionic acid can be decreased when combined with Indinavir.
5-androstenedione
Major
The metabolism of 5-androstenedione can be decreased when combined with Indinavir.
Crixivan Toxicity & Overdose RiskOverdosing on this drug can lead to heart attack and chest pain.
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Crixivan Novel Uses: Which Conditions Have a Clinical Trial Featuring Crixivan?

43 active clinical trials are ongoing to assess the potential of Crixivan in treating HIV (Human Immunodeficiency Virus).
Condition
Clinical Trials
Trial Phases
HIV
41 Actively Recruiting
Phase 2, Phase 3, Early Phase 1, Phase 1, Not Applicable, Phase 4

Crixivan Reviews: What are patients saying about Crixivan?

5Patient Review
3/22/2010
Crixivan for HIV
I've been on this medication for over a decade and it's really helped me.
3.7Patient Review
4/5/2009
Crixivan for Prevention of HIV Infection after Exposure
I was given three different antibiotics and thirteen pills to take all at once. I came into contact with the virus again, and now I'm sure of where it came from. The doctor didn't give me any information on how to get the prescription again, so now I'm stuck.
1.7Patient Review
4/14/2009
Crixivan for HIV
Crixivan is pure poison. I took it years ago and it's still giving me lipodystrophy problems that require surgery.
1Patient Review
9/12/2011
Crixivan for Prevention of HIV Infection after Exposure
I felt incredibly nauseous after taking this medication.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about crixivan

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is the generic name for Crixivan?

"CRIXIVAN prevents HIV from multiplying by inhibiting the protease enzyme."

Answered by AI

Is indinavir still used?

"Newer drugs that are more convenient to take, less likely to promote virus resistance, and less toxic are replacing it."

Answered by AI

Is Crixivan discontinued?

"Crixivan was one of the first HIV ARV medications approved by the FDA, but due to side effects and medication interactions, it has not been a first choice treatment option for many years and has been discontinued in the U.S."

Answered by AI

What are the side effects of Crixivan?

"Possible side effects include: -Stomach pain -Nausea -Vomiting -Diarrhea -Indigestion -Heartburn -Appetite changes -Headache -Dizziness -Weakness or fatigue -Back pain -Rash -Itching -Dry skin -Altered sense of taste -Cold symptoms such as a stuffy nose, sneezing, or a sore throat"

Answered by AI

Clinical Trials for Crixivan

Have you considered Crixivan clinical trials? We made a collection of clinical trials featuring Crixivan, we think they might fit your search criteria.
Have you considered Crixivan clinical trials? We made a collection of clinical trials featuring Crixivan, we think they might fit your search criteria.
Have you considered Crixivan clinical trials? We made a collection of clinical trials featuring Crixivan, we think they might fit your search criteria.
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