Clindagel

Babesiosis, Mitral Valve Prolapse, Toxoplasmosis + 39 more

Treatment

18 Active Studies for Clindagel

What is Clindagel

Clindamycin

The Generic name of this drug

Treatment Summary

Clindamycin is an antibiotic used to treat bacterial infections. It is derived from lincomycin and has similar effects, but offers better results. Clindamycin can be used to treat a variety of serious infections, as well as acne. It works by attacking both gram-positive and gram-negative bacteria. Additionally, it has been used off-label to treat toxoplasmosis, malaria, and babesiosis. The drug was first isolated in Lincoln, Nebraska from soil samples.

Cleocin Hydrochloride

is the brand name

Clindagel Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Cleocin Hydrochloride

Clindamycin

1970

507

Effectiveness

How Clindagel Affects Patients

Clindamycin works by stopping bacteria from making proteins, which helps prevent the spread of infection. It needs to be taken every six hours to be effective. It is important to be aware that Clostridium difficile associated diarrhea (CDAD) can occur with clindamycin, and can range from mild diarrhea to fatal colitis, so it should only be used for serious infections when other less toxic antibiotics are not available. Clindamycin is active against some gram-positive bacteria, as well as both gram-positive and gram-negative anaerobes, but resistance may develop over time. To make sure

How Clindagel works in the body

Clindamycin works by preventing bacteria from making proteins. It does this by attaching to the ribosome, a structure that helps make proteins from amino acids. Clindamycin has a structure similar to certain molecules that are important in protein production, so it can fit in their place and block the process. Clindamycin also kills a type of bacteria called Propionibacterium acnes, which has been linked to acne.

When to interrupt dosage

The prescribed measure of Clindagel is contingent upon the recognized condition, including viridans group streptococci, Vaginal Infections and Surgical Intervention. The dose of dosage necessitates the administration technique (e.g. Cream - Vaginal or Suspension - Topical) outlined in the accompanying table.

Condition

Dosage

Administration

Acne Vulgaris

150.0 mg, 300.0 mg, , 0.02 mg/mg, 75.0 mg/mL, 150.0 mg/mL, 75.0 mg, 0.01 mg/mg, 10.0 mg/mL, 6.0 mg/mL, 12.0 mg/mL, 18.0 mg/mL, 100.0 mg/mL, 10.0 mg, 0.1 mg/mg, 100.0 mg, 1.0 %, 1.2 %, 30.0 mg/mL, 60.0 mg/mL, 90.0 mg/mL, 0.012 mg/mg, 11.9 mg/mL, 5.0 mg/mg, 0.007 mg/mg, 0.01 mg/mL

, Capsule - Oral, Oral, Capsule, Vaginal, Cream, Cream - Vaginal, Granule, for solution, Granule, for solution - Oral, Topical, Gel - Topical, Gel, Suspension, Suspension - Topical, Injection, solution - Intravenous, Injection, solution, Intravenous, Solution, Swab, Swab - Topical, Kit, Kit - Topical, Aerosol, foam - Topical, Aerosol, foam, Intramuscular; Intravenous, Injection, solution - Intramuscular; Intravenous, Lotion, Lotion - Topical, Suppository, Suppository - Vaginal, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Kit - Intramuscular; Intravenous, Powder, for solution - Oral, Solution - Intramuscular; Intravenous, Solution - Intravenous, Cream - Topical, Solution - Topical, Injection, Injection - Intravenous, Powder, for solution, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Solution - Oral, Liquid, Liquid - Intramuscular; Intravenous, Injection - Intramuscular; Intravenous, Injection, solution, concentrate - Intramuscular; Intravenous, Kit - Infiltration; Intramuscular; Intravenous, Infiltration; Intramuscular; Intravenous, Gel - Vaginal

Surgical Intervention

150.0 mg, 300.0 mg, , 0.02 mg/mg, 75.0 mg/mL, 150.0 mg/mL, 75.0 mg, 0.01 mg/mg, 10.0 mg/mL, 6.0 mg/mL, 12.0 mg/mL, 18.0 mg/mL, 100.0 mg/mL, 10.0 mg, 0.1 mg/mg, 100.0 mg, 1.0 %, 1.2 %, 30.0 mg/mL, 60.0 mg/mL, 90.0 mg/mL, 0.012 mg/mg, 11.9 mg/mL, 5.0 mg/mg, 0.007 mg/mg, 0.01 mg/mL

, Capsule - Oral, Oral, Capsule, Vaginal, Cream, Cream - Vaginal, Granule, for solution, Granule, for solution - Oral, Topical, Gel - Topical, Gel, Suspension, Suspension - Topical, Injection, solution - Intravenous, Injection, solution, Intravenous, Solution, Swab, Swab - Topical, Kit, Kit - Topical, Aerosol, foam - Topical, Aerosol, foam, Intramuscular; Intravenous, Injection, solution - Intramuscular; Intravenous, Lotion, Lotion - Topical, Suppository, Suppository - Vaginal, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Kit - Intramuscular; Intravenous, Powder, for solution - Oral, Solution - Intramuscular; Intravenous, Solution - Intravenous, Cream - Topical, Solution - Topical, Injection, Injection - Intravenous, Powder, for solution, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Solution - Oral, Liquid, Liquid - Intramuscular; Intravenous, Injection - Intramuscular; Intravenous, Injection, solution, concentrate - Intramuscular; Intravenous, Kit - Infiltration; Intramuscular; Intravenous, Infiltration; Intramuscular; Intravenous, Gel - Vaginal

Acquired valvular dysfunction

150.0 mg, 300.0 mg, , 0.02 mg/mg, 75.0 mg/mL, 150.0 mg/mL, 75.0 mg, 0.01 mg/mg, 10.0 mg/mL, 6.0 mg/mL, 12.0 mg/mL, 18.0 mg/mL, 100.0 mg/mL, 10.0 mg, 0.1 mg/mg, 100.0 mg, 1.0 %, 1.2 %, 30.0 mg/mL, 60.0 mg/mL, 90.0 mg/mL, 0.012 mg/mg, 11.9 mg/mL, 5.0 mg/mg, 0.007 mg/mg, 0.01 mg/mL

, Capsule - Oral, Oral, Capsule, Vaginal, Cream, Cream - Vaginal, Granule, for solution, Granule, for solution - Oral, Topical, Gel - Topical, Gel, Suspension, Suspension - Topical, Injection, solution - Intravenous, Injection, solution, Intravenous, Solution, Swab, Swab - Topical, Kit, Kit - Topical, Aerosol, foam - Topical, Aerosol, foam, Intramuscular; Intravenous, Injection, solution - Intramuscular; Intravenous, Lotion, Lotion - Topical, Suppository, Suppository - Vaginal, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Kit - Intramuscular; Intravenous, Powder, for solution - Oral, Solution - Intramuscular; Intravenous, Solution - Intravenous, Cream - Topical, Solution - Topical, Injection, Injection - Intravenous, Powder, for solution, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Solution - Oral, Liquid, Liquid - Intramuscular; Intravenous, Injection - Intramuscular; Intravenous, Injection, solution, concentrate - Intramuscular; Intravenous, Kit - Infiltration; Intramuscular; Intravenous, Infiltration; Intramuscular; Intravenous, Gel - Vaginal

Respiratory Tract Infections

150.0 mg, 300.0 mg, , 0.02 mg/mg, 75.0 mg/mL, 150.0 mg/mL, 75.0 mg, 0.01 mg/mg, 10.0 mg/mL, 6.0 mg/mL, 12.0 mg/mL, 18.0 mg/mL, 100.0 mg/mL, 10.0 mg, 0.1 mg/mg, 100.0 mg, 1.0 %, 1.2 %, 30.0 mg/mL, 60.0 mg/mL, 90.0 mg/mL, 0.012 mg/mg, 11.9 mg/mL, 5.0 mg/mg, 0.007 mg/mg, 0.01 mg/mL

, Capsule - Oral, Oral, Capsule, Vaginal, Cream, Cream - Vaginal, Granule, for solution, Granule, for solution - Oral, Topical, Gel - Topical, Gel, Suspension, Suspension - Topical, Injection, solution - Intravenous, Injection, solution, Intravenous, Solution, Swab, Swab - Topical, Kit, Kit - Topical, Aerosol, foam - Topical, Aerosol, foam, Intramuscular; Intravenous, Injection, solution - Intramuscular; Intravenous, Lotion, Lotion - Topical, Suppository, Suppository - Vaginal, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Kit - Intramuscular; Intravenous, Powder, for solution - Oral, Solution - Intramuscular; Intravenous, Solution - Intravenous, Cream - Topical, Solution - Topical, Injection, Injection - Intravenous, Powder, for solution, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Solution - Oral, Liquid, Liquid - Intramuscular; Intravenous, Injection - Intramuscular; Intravenous, Injection, solution, concentrate - Intramuscular; Intravenous, Kit - Infiltration; Intramuscular; Intravenous, Infiltration; Intramuscular; Intravenous, Gel - Vaginal

Bone and Bones

150.0 mg, 300.0 mg, , 0.02 mg/mg, 75.0 mg/mL, 150.0 mg/mL, 75.0 mg, 0.01 mg/mg, 10.0 mg/mL, 6.0 mg/mL, 12.0 mg/mL, 18.0 mg/mL, 100.0 mg/mL, 10.0 mg, 0.1 mg/mg, 100.0 mg, 1.0 %, 1.2 %, 30.0 mg/mL, 60.0 mg/mL, 90.0 mg/mL, 0.012 mg/mg, 11.9 mg/mL, 5.0 mg/mg, 0.007 mg/mg, 0.01 mg/mL

, Capsule - Oral, Oral, Capsule, Vaginal, Cream, Cream - Vaginal, Granule, for solution, Granule, for solution - Oral, Topical, Gel - Topical, Gel, Suspension, Suspension - Topical, Injection, solution - Intravenous, Injection, solution, Intravenous, Solution, Swab, Swab - Topical, Kit, Kit - Topical, Aerosol, foam - Topical, Aerosol, foam, Intramuscular; Intravenous, Injection, solution - Intramuscular; Intravenous, Lotion, Lotion - Topical, Suppository, Suppository - Vaginal, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Kit - Intramuscular; Intravenous, Powder, for solution - Oral, Solution - Intramuscular; Intravenous, Solution - Intravenous, Cream - Topical, Solution - Topical, Injection, Injection - Intravenous, Powder, for solution, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Solution - Oral, Liquid, Liquid - Intramuscular; Intravenous, Injection - Intramuscular; Intravenous, Injection, solution, concentrate - Intramuscular; Intravenous, Kit - Infiltration; Intramuscular; Intravenous, Infiltration; Intramuscular; Intravenous, Gel - Vaginal

Bacteria, Anaerobic

150.0 mg, 300.0 mg, , 0.02 mg/mg, 75.0 mg/mL, 150.0 mg/mL, 75.0 mg, 0.01 mg/mg, 10.0 mg/mL, 6.0 mg/mL, 12.0 mg/mL, 18.0 mg/mL, 100.0 mg/mL, 10.0 mg, 0.1 mg/mg, 100.0 mg, 1.0 %, 1.2 %, 30.0 mg/mL, 60.0 mg/mL, 90.0 mg/mL, 0.012 mg/mg, 11.9 mg/mL, 5.0 mg/mg, 0.007 mg/mg, 0.01 mg/mL

, Capsule - Oral, Oral, Capsule, Vaginal, Cream, Cream - Vaginal, Granule, for solution, Granule, for solution - Oral, Topical, Gel - Topical, Gel, Suspension, Suspension - Topical, Injection, solution - Intravenous, Injection, solution, Intravenous, Solution, Swab, Swab - Topical, Kit, Kit - Topical, Aerosol, foam - Topical, Aerosol, foam, Intramuscular; Intravenous, Injection, solution - Intramuscular; Intravenous, Lotion, Lotion - Topical, Suppository, Suppository - Vaginal, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Kit - Intramuscular; Intravenous, Powder, for solution - Oral, Solution - Intramuscular; Intravenous, Solution - Intravenous, Cream - Topical, Solution - Topical, Injection, Injection - Intravenous, Powder, for solution, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Solution - Oral, Liquid, Liquid - Intramuscular; Intravenous, Injection - Intramuscular; Intravenous, Injection, solution, concentrate - Intramuscular; Intravenous, Kit - Infiltration; Intramuscular; Intravenous, Infiltration; Intramuscular; Intravenous, Gel - Vaginal

Endometritis caused by Anaerobic Bacterial Infection

150.0 mg, 300.0 mg, , 0.02 mg/mg, 75.0 mg/mL, 150.0 mg/mL, 75.0 mg, 0.01 mg/mg, 10.0 mg/mL, 6.0 mg/mL, 12.0 mg/mL, 18.0 mg/mL, 100.0 mg/mL, 10.0 mg, 0.1 mg/mg, 100.0 mg, 1.0 %, 1.2 %, 30.0 mg/mL, 60.0 mg/mL, 90.0 mg/mL, 0.012 mg/mg, 11.9 mg/mL, 5.0 mg/mg, 0.007 mg/mg, 0.01 mg/mL

, Capsule - Oral, Oral, Capsule, Vaginal, Cream, Cream - Vaginal, Granule, for solution, Granule, for solution - Oral, Topical, Gel - Topical, Gel, Suspension, Suspension - Topical, Injection, solution - Intravenous, Injection, solution, Intravenous, Solution, Swab, Swab - Topical, Kit, Kit - Topical, Aerosol, foam - Topical, Aerosol, foam, Intramuscular; Intravenous, Injection, solution - Intramuscular; Intravenous, Lotion, Lotion - Topical, Suppository, Suppository - Vaginal, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Kit - Intramuscular; Intravenous, Powder, for solution - Oral, Solution - Intramuscular; Intravenous, Solution - Intravenous, Cream - Topical, Solution - Topical, Injection, Injection - Intravenous, Powder, for solution, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Solution - Oral, Liquid, Liquid - Intramuscular; Intravenous, Injection - Intramuscular; Intravenous, Injection, solution, concentrate - Intramuscular; Intravenous, Kit - Infiltration; Intramuscular; Intravenous, Infiltration; Intramuscular; Intravenous, Gel - Vaginal

viridans group streptococci

150.0 mg, 300.0 mg, , 0.02 mg/mg, 75.0 mg/mL, 150.0 mg/mL, 75.0 mg, 0.01 mg/mg, 10.0 mg/mL, 6.0 mg/mL, 12.0 mg/mL, 18.0 mg/mL, 100.0 mg/mL, 10.0 mg, 0.1 mg/mg, 100.0 mg, 1.0 %, 1.2 %, 30.0 mg/mL, 60.0 mg/mL, 90.0 mg/mL, 0.012 mg/mg, 11.9 mg/mL, 5.0 mg/mg, 0.007 mg/mg, 0.01 mg/mL

, Capsule - Oral, Oral, Capsule, Vaginal, Cream, Cream - Vaginal, Granule, for solution, Granule, for solution - Oral, Topical, Gel - Topical, Gel, Suspension, Suspension - Topical, Injection, solution - Intravenous, Injection, solution, Intravenous, Solution, Swab, Swab - Topical, Kit, Kit - Topical, Aerosol, foam - Topical, Aerosol, foam, Intramuscular; Intravenous, Injection, solution - Intramuscular; Intravenous, Lotion, Lotion - Topical, Suppository, Suppository - Vaginal, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Kit - Intramuscular; Intravenous, Powder, for solution - Oral, Solution - Intramuscular; Intravenous, Solution - Intravenous, Cream - Topical, Solution - Topical, Injection, Injection - Intravenous, Powder, for solution, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Solution - Oral, Liquid, Liquid - Intramuscular; Intravenous, Injection - Intramuscular; Intravenous, Injection, solution, concentrate - Intramuscular; Intravenous, Kit - Infiltration; Intramuscular; Intravenous, Infiltration; Intramuscular; Intravenous, Gel - Vaginal

Bone and Bones

150.0 mg, 300.0 mg, , 0.02 mg/mg, 75.0 mg/mL, 150.0 mg/mL, 75.0 mg, 0.01 mg/mg, 10.0 mg/mL, 6.0 mg/mL, 12.0 mg/mL, 18.0 mg/mL, 100.0 mg/mL, 10.0 mg, 0.1 mg/mg, 100.0 mg, 1.0 %, 1.2 %, 30.0 mg/mL, 60.0 mg/mL, 90.0 mg/mL, 0.012 mg/mg, 11.9 mg/mL, 5.0 mg/mg, 0.007 mg/mg, 0.01 mg/mL

, Capsule - Oral, Oral, Capsule, Vaginal, Cream, Cream - Vaginal, Granule, for solution, Granule, for solution - Oral, Topical, Gel - Topical, Gel, Suspension, Suspension - Topical, Injection, solution - Intravenous, Injection, solution, Intravenous, Solution, Swab, Swab - Topical, Kit, Kit - Topical, Aerosol, foam - Topical, Aerosol, foam, Intramuscular; Intravenous, Injection, solution - Intramuscular; Intravenous, Lotion, Lotion - Topical, Suppository, Suppository - Vaginal, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Kit - Intramuscular; Intravenous, Powder, for solution - Oral, Solution - Intramuscular; Intravenous, Solution - Intravenous, Cream - Topical, Solution - Topical, Injection, Injection - Intravenous, Powder, for solution, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Solution - Oral, Liquid, Liquid - Intramuscular; Intravenous, Injection - Intramuscular; Intravenous, Injection, solution, concentrate - Intramuscular; Intravenous, Kit - Infiltration; Intramuscular; Intravenous, Infiltration; Intramuscular; Intravenous, Gel - Vaginal

Bacterial Endocarditis

150.0 mg, 300.0 mg, , 0.02 mg/mg, 75.0 mg/mL, 150.0 mg/mL, 75.0 mg, 0.01 mg/mg, 10.0 mg/mL, 6.0 mg/mL, 12.0 mg/mL, 18.0 mg/mL, 100.0 mg/mL, 10.0 mg, 0.1 mg/mg, 100.0 mg, 1.0 %, 1.2 %, 30.0 mg/mL, 60.0 mg/mL, 90.0 mg/mL, 0.012 mg/mg, 11.9 mg/mL, 5.0 mg/mg, 0.007 mg/mg, 0.01 mg/mL

, Capsule - Oral, Oral, Capsule, Vaginal, Cream, Cream - Vaginal, Granule, for solution, Granule, for solution - Oral, Topical, Gel - Topical, Gel, Suspension, Suspension - Topical, Injection, solution - Intravenous, Injection, solution, Intravenous, Solution, Swab, Swab - Topical, Kit, Kit - Topical, Aerosol, foam - Topical, Aerosol, foam, Intramuscular; Intravenous, Injection, solution - Intramuscular; Intravenous, Lotion, Lotion - Topical, Suppository, Suppository - Vaginal, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Kit - Intramuscular; Intravenous, Powder, for solution - Oral, Solution - Intramuscular; Intravenous, Solution - Intravenous, Cream - Topical, Solution - Topical, Injection, Injection - Intravenous, Powder, for solution, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Solution - Oral, Liquid, Liquid - Intramuscular; Intravenous, Injection - Intramuscular; Intravenous, Injection, solution, concentrate - Intramuscular; Intravenous, Kit - Infiltration; Intramuscular; Intravenous, Infiltration; Intramuscular; Intravenous, Gel - Vaginal

prophylaxis of Bacterial endocarditis

150.0 mg, 300.0 mg, , 0.02 mg/mg, 75.0 mg/mL, 150.0 mg/mL, 75.0 mg, 0.01 mg/mg, 10.0 mg/mL, 6.0 mg/mL, 12.0 mg/mL, 18.0 mg/mL, 100.0 mg/mL, 10.0 mg, 0.1 mg/mg, 100.0 mg, 1.0 %, 1.2 %, 30.0 mg/mL, 60.0 mg/mL, 90.0 mg/mL, 0.012 mg/mg, 11.9 mg/mL, 5.0 mg/mg, 0.007 mg/mg, 0.01 mg/mL

, Capsule - Oral, Oral, Capsule, Vaginal, Cream, Cream - Vaginal, Granule, for solution, Granule, for solution - Oral, Topical, Gel - Topical, Gel, Suspension, Suspension - Topical, Injection, solution - Intravenous, Injection, solution, Intravenous, Solution, Swab, Swab - Topical, Kit, Kit - Topical, Aerosol, foam - Topical, Aerosol, foam, Intramuscular; Intravenous, Injection, solution - Intramuscular; Intravenous, Lotion, Lotion - Topical, Suppository, Suppository - Vaginal, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Kit - Intramuscular; Intravenous, Powder, for solution - Oral, Solution - Intramuscular; Intravenous, Solution - Intravenous, Cream - Topical, Solution - Topical, Injection, Injection - Intravenous, Powder, for solution, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Solution - Oral, Liquid, Liquid - Intramuscular; Intravenous, Injection - Intramuscular; Intravenous, Injection, solution, concentrate - Intramuscular; Intravenous, Kit - Infiltration; Intramuscular; Intravenous, Infiltration; Intramuscular; Intravenous, Gel - Vaginal

Malaria

150.0 mg, 300.0 mg, , 0.02 mg/mg, 75.0 mg/mL, 150.0 mg/mL, 75.0 mg, 0.01 mg/mg, 10.0 mg/mL, 6.0 mg/mL, 12.0 mg/mL, 18.0 mg/mL, 100.0 mg/mL, 10.0 mg, 0.1 mg/mg, 100.0 mg, 1.0 %, 1.2 %, 30.0 mg/mL, 60.0 mg/mL, 90.0 mg/mL, 0.012 mg/mg, 11.9 mg/mL, 5.0 mg/mg, 0.007 mg/mg, 0.01 mg/mL

, Capsule - Oral, Oral, Capsule, Vaginal, Cream, Cream - Vaginal, Granule, for solution, Granule, for solution - Oral, Topical, Gel - Topical, Gel, Suspension, Suspension - Topical, Injection, solution - Intravenous, Injection, solution, Intravenous, Solution, Swab, Swab - Topical, Kit, Kit - Topical, Aerosol, foam - Topical, Aerosol, foam, Intramuscular; Intravenous, Injection, solution - Intramuscular; Intravenous, Lotion, Lotion - Topical, Suppository, Suppository - Vaginal, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Kit - Intramuscular; Intravenous, Powder, for solution - Oral, Solution - Intramuscular; Intravenous, Solution - Intravenous, Cream - Topical, Solution - Topical, Injection, Injection - Intravenous, Powder, for solution, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Solution - Oral, Liquid, Liquid - Intramuscular; Intravenous, Injection - Intramuscular; Intravenous, Injection, solution, concentrate - Intramuscular; Intravenous, Kit - Infiltration; Intramuscular; Intravenous, Infiltration; Intramuscular; Intravenous, Gel - Vaginal

Candidiasis, Vulvovaginal

150.0 mg, 300.0 mg, , 0.02 mg/mg, 75.0 mg/mL, 150.0 mg/mL, 75.0 mg, 0.01 mg/mg, 10.0 mg/mL, 6.0 mg/mL, 12.0 mg/mL, 18.0 mg/mL, 100.0 mg/mL, 10.0 mg, 0.1 mg/mg, 100.0 mg, 1.0 %, 1.2 %, 30.0 mg/mL, 60.0 mg/mL, 90.0 mg/mL, 0.012 mg/mg, 11.9 mg/mL, 5.0 mg/mg, 0.007 mg/mg, 0.01 mg/mL

, Capsule - Oral, Oral, Capsule, Vaginal, Cream, Cream - Vaginal, Granule, for solution, Granule, for solution - Oral, Topical, Gel - Topical, Gel, Suspension, Suspension - Topical, Injection, solution - Intravenous, Injection, solution, Intravenous, Solution, Swab, Swab - Topical, Kit, Kit - Topical, Aerosol, foam - Topical, Aerosol, foam, Intramuscular; Intravenous, Injection, solution - Intramuscular; Intravenous, Lotion, Lotion - Topical, Suppository, Suppository - Vaginal, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Kit - Intramuscular; Intravenous, Powder, for solution - Oral, Solution - Intramuscular; Intravenous, Solution - Intravenous, Cream - Topical, Solution - Topical, Injection, Injection - Intravenous, Powder, for solution, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Solution - Oral, Liquid, Liquid - Intramuscular; Intravenous, Injection - Intramuscular; Intravenous, Injection, solution, concentrate - Intramuscular; Intravenous, Kit - Infiltration; Intramuscular; Intravenous, Infiltration; Intramuscular; Intravenous, Gel - Vaginal

Pneumonia, Pneumocystis

150.0 mg, 300.0 mg, , 0.02 mg/mg, 75.0 mg/mL, 150.0 mg/mL, 75.0 mg, 0.01 mg/mg, 10.0 mg/mL, 6.0 mg/mL, 12.0 mg/mL, 18.0 mg/mL, 100.0 mg/mL, 10.0 mg, 0.1 mg/mg, 100.0 mg, 1.0 %, 1.2 %, 30.0 mg/mL, 60.0 mg/mL, 90.0 mg/mL, 0.012 mg/mg, 11.9 mg/mL, 5.0 mg/mg, 0.007 mg/mg, 0.01 mg/mL

, Capsule - Oral, Oral, Capsule, Vaginal, Cream, Cream - Vaginal, Granule, for solution, Granule, for solution - Oral, Topical, Gel - Topical, Gel, Suspension, Suspension - Topical, Injection, solution - Intravenous, Injection, solution, Intravenous, Solution, Swab, Swab - Topical, Kit, Kit - Topical, Aerosol, foam - Topical, Aerosol, foam, Intramuscular; Intravenous, Injection, solution - Intramuscular; Intravenous, Lotion, Lotion - Topical, Suppository, Suppository - Vaginal, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Kit - Intramuscular; Intravenous, Powder, for solution - Oral, Solution - Intramuscular; Intravenous, Solution - Intravenous, Cream - Topical, Solution - Topical, Injection, Injection - Intravenous, Powder, for solution, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Solution - Oral, Liquid, Liquid - Intramuscular; Intravenous, Injection - Intramuscular; Intravenous, Injection, solution, concentrate - Intramuscular; Intravenous, Kit - Infiltration; Intramuscular; Intravenous, Infiltration; Intramuscular; Intravenous, Gel - Vaginal

Bacteria, Anaerobic

150.0 mg, 300.0 mg, , 0.02 mg/mg, 75.0 mg/mL, 150.0 mg/mL, 75.0 mg, 0.01 mg/mg, 10.0 mg/mL, 6.0 mg/mL, 12.0 mg/mL, 18.0 mg/mL, 100.0 mg/mL, 10.0 mg, 0.1 mg/mg, 100.0 mg, 1.0 %, 1.2 %, 30.0 mg/mL, 60.0 mg/mL, 90.0 mg/mL, 0.012 mg/mg, 11.9 mg/mL, 5.0 mg/mg, 0.007 mg/mg, 0.01 mg/mL

, Capsule - Oral, Oral, Capsule, Vaginal, Cream, Cream - Vaginal, Granule, for solution, Granule, for solution - Oral, Topical, Gel - Topical, Gel, Suspension, Suspension - Topical, Injection, solution - Intravenous, Injection, solution, Intravenous, Solution, Swab, Swab - Topical, Kit, Kit - Topical, Aerosol, foam - Topical, Aerosol, foam, Intramuscular; Intravenous, Injection, solution - Intramuscular; Intravenous, Lotion, Lotion - Topical, Suppository, Suppository - Vaginal, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Kit - Intramuscular; Intravenous, Powder, for solution - Oral, Solution - Intramuscular; Intravenous, Solution - Intravenous, Cream - Topical, Solution - Topical, Injection, Injection - Intravenous, Powder, for solution, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Solution - Oral, Liquid, Liquid - Intramuscular; Intravenous, Injection - Intramuscular; Intravenous, Injection, solution, concentrate - Intramuscular; Intravenous, Kit - Infiltration; Intramuscular; Intravenous, Infiltration; Intramuscular; Intravenous, Gel - Vaginal

Heart Defects, Congenital

150.0 mg, 300.0 mg, , 0.02 mg/mg, 75.0 mg/mL, 150.0 mg/mL, 75.0 mg, 0.01 mg/mg, 10.0 mg/mL, 6.0 mg/mL, 12.0 mg/mL, 18.0 mg/mL, 100.0 mg/mL, 10.0 mg, 0.1 mg/mg, 100.0 mg, 1.0 %, 1.2 %, 30.0 mg/mL, 60.0 mg/mL, 90.0 mg/mL, 0.012 mg/mg, 11.9 mg/mL, 5.0 mg/mg, 0.007 mg/mg, 0.01 mg/mL

, Capsule - Oral, Oral, Capsule, Vaginal, Cream, Cream - Vaginal, Granule, for solution, Granule, for solution - Oral, Topical, Gel - Topical, Gel, Suspension, Suspension - Topical, Injection, solution - Intravenous, Injection, solution, Intravenous, Solution, Swab, Swab - Topical, Kit, Kit - Topical, Aerosol, foam - Topical, Aerosol, foam, Intramuscular; Intravenous, Injection, solution - Intramuscular; Intravenous, Lotion, Lotion - Topical, Suppository, Suppository - Vaginal, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Kit - Intramuscular; Intravenous, Powder, for solution - Oral, Solution - Intramuscular; Intravenous, Solution - Intravenous, Cream - Topical, Solution - Topical, Injection, Injection - Intravenous, Powder, for solution, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Solution - Oral, Liquid, Liquid - Intramuscular; Intravenous, Injection - Intramuscular; Intravenous, Injection, solution, concentrate - Intramuscular; Intravenous, Kit - Infiltration; Intramuscular; Intravenous, Infiltration; Intramuscular; Intravenous, Gel - Vaginal

Heart Valve Prosthesis

150.0 mg, 300.0 mg, , 0.02 mg/mg, 75.0 mg/mL, 150.0 mg/mL, 75.0 mg, 0.01 mg/mg, 10.0 mg/mL, 6.0 mg/mL, 12.0 mg/mL, 18.0 mg/mL, 100.0 mg/mL, 10.0 mg, 0.1 mg/mg, 100.0 mg, 1.0 %, 1.2 %, 30.0 mg/mL, 60.0 mg/mL, 90.0 mg/mL, 0.012 mg/mg, 11.9 mg/mL, 5.0 mg/mg, 0.007 mg/mg, 0.01 mg/mL

, Capsule - Oral, Oral, Capsule, Vaginal, Cream, Cream - Vaginal, Granule, for solution, Granule, for solution - Oral, Topical, Gel - Topical, Gel, Suspension, Suspension - Topical, Injection, solution - Intravenous, Injection, solution, Intravenous, Solution, Swab, Swab - Topical, Kit, Kit - Topical, Aerosol, foam - Topical, Aerosol, foam, Intramuscular; Intravenous, Injection, solution - Intramuscular; Intravenous, Lotion, Lotion - Topical, Suppository, Suppository - Vaginal, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Kit - Intramuscular; Intravenous, Powder, for solution - Oral, Solution - Intramuscular; Intravenous, Solution - Intravenous, Cream - Topical, Solution - Topical, Injection, Injection - Intravenous, Powder, for solution, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Solution - Oral, Liquid, Liquid - Intramuscular; Intravenous, Injection - Intramuscular; Intravenous, Injection, solution, concentrate - Intramuscular; Intravenous, Kit - Infiltration; Intramuscular; Intravenous, Infiltration; Intramuscular; Intravenous, Gel - Vaginal

Acne Vulgaris

150.0 mg, 300.0 mg, , 0.02 mg/mg, 75.0 mg/mL, 150.0 mg/mL, 75.0 mg, 0.01 mg/mg, 10.0 mg/mL, 6.0 mg/mL, 12.0 mg/mL, 18.0 mg/mL, 100.0 mg/mL, 10.0 mg, 0.1 mg/mg, 100.0 mg, 1.0 %, 1.2 %, 30.0 mg/mL, 60.0 mg/mL, 90.0 mg/mL, 0.012 mg/mg, 11.9 mg/mL, 5.0 mg/mg, 0.007 mg/mg, 0.01 mg/mL

, Capsule - Oral, Oral, Capsule, Vaginal, Cream, Cream - Vaginal, Granule, for solution, Granule, for solution - Oral, Topical, Gel - Topical, Gel, Suspension, Suspension - Topical, Injection, solution - Intravenous, Injection, solution, Intravenous, Solution, Swab, Swab - Topical, Kit, Kit - Topical, Aerosol, foam - Topical, Aerosol, foam, Intramuscular; Intravenous, Injection, solution - Intramuscular; Intravenous, Lotion, Lotion - Topical, Suppository, Suppository - Vaginal, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Kit - Intramuscular; Intravenous, Powder, for solution - Oral, Solution - Intramuscular; Intravenous, Solution - Intravenous, Cream - Topical, Solution - Topical, Injection, Injection - Intravenous, Powder, for solution, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Solution - Oral, Liquid, Liquid - Intramuscular; Intravenous, Injection - Intramuscular; Intravenous, Injection, solution, concentrate - Intramuscular; Intravenous, Kit - Infiltration; Intramuscular; Intravenous, Infiltration; Intramuscular; Intravenous, Gel - Vaginal

penicillins

150.0 mg, 300.0 mg, , 0.02 mg/mg, 75.0 mg/mL, 150.0 mg/mL, 75.0 mg, 0.01 mg/mg, 10.0 mg/mL, 6.0 mg/mL, 12.0 mg/mL, 18.0 mg/mL, 100.0 mg/mL, 10.0 mg, 0.1 mg/mg, 100.0 mg, 1.0 %, 1.2 %, 30.0 mg/mL, 60.0 mg/mL, 90.0 mg/mL, 0.012 mg/mg, 11.9 mg/mL, 5.0 mg/mg, 0.007 mg/mg, 0.01 mg/mL

, Capsule - Oral, Oral, Capsule, Vaginal, Cream, Cream - Vaginal, Granule, for solution, Granule, for solution - Oral, Topical, Gel - Topical, Gel, Suspension, Suspension - Topical, Injection, solution - Intravenous, Injection, solution, Intravenous, Solution, Swab, Swab - Topical, Kit, Kit - Topical, Aerosol, foam - Topical, Aerosol, foam, Intramuscular; Intravenous, Injection, solution - Intramuscular; Intravenous, Lotion, Lotion - Topical, Suppository, Suppository - Vaginal, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Kit - Intramuscular; Intravenous, Powder, for solution - Oral, Solution - Intramuscular; Intravenous, Solution - Intravenous, Cream - Topical, Solution - Topical, Injection, Injection - Intravenous, Powder, for solution, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Solution - Oral, Liquid, Liquid - Intramuscular; Intravenous, Injection - Intramuscular; Intravenous, Injection, solution, concentrate - Intramuscular; Intravenous, Kit - Infiltration; Intramuscular; Intravenous, Infiltration; Intramuscular; Intravenous, Gel - Vaginal

Hypertrophic Cardiomyopathy

150.0 mg, 300.0 mg, , 0.02 mg/mg, 75.0 mg/mL, 150.0 mg/mL, 75.0 mg, 0.01 mg/mg, 10.0 mg/mL, 6.0 mg/mL, 12.0 mg/mL, 18.0 mg/mL, 100.0 mg/mL, 10.0 mg, 0.1 mg/mg, 100.0 mg, 1.0 %, 1.2 %, 30.0 mg/mL, 60.0 mg/mL, 90.0 mg/mL, 0.012 mg/mg, 11.9 mg/mL, 5.0 mg/mg, 0.007 mg/mg, 0.01 mg/mL

, Capsule - Oral, Oral, Capsule, Vaginal, Cream, Cream - Vaginal, Granule, for solution, Granule, for solution - Oral, Topical, Gel - Topical, Gel, Suspension, Suspension - Topical, Injection, solution - Intravenous, Injection, solution, Intravenous, Solution, Swab, Swab - Topical, Kit, Kit - Topical, Aerosol, foam - Topical, Aerosol, foam, Intramuscular; Intravenous, Injection, solution - Intramuscular; Intravenous, Lotion, Lotion - Topical, Suppository, Suppository - Vaginal, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Kit - Intramuscular; Intravenous, Powder, for solution - Oral, Solution - Intramuscular; Intravenous, Solution - Intravenous, Cream - Topical, Solution - Topical, Injection, Injection - Intravenous, Powder, for solution, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Solution - Oral, Liquid, Liquid - Intramuscular; Intravenous, Injection - Intramuscular; Intravenous, Injection, solution, concentrate - Intramuscular; Intravenous, Kit - Infiltration; Intramuscular; Intravenous, Infiltration; Intramuscular; Intravenous, Gel - Vaginal

Warnings

Clindagel Contraindications

Condition

Risk Level

Notes

Enterocolitis, Pseudomembranous

Do Not Combine

Crohn Disease

Do Not Combine

Ulcerative Colitis

Do Not Combine

Severe Hypersensitivity Reactions

Do Not Combine

Clindamycin may interact with Pulse Frequency

There are 20 known major drug interactions with Clindagel.

Common Clindagel Drug Interactions

Drug Name

Risk Level

Description

Astemizole

Major

The metabolism of Astemizole can be decreased when combined with Clindamycin.

Axitinib

Major

The metabolism of Axitinib can be decreased when combined with Clindamycin.

Bromocriptine

Major

The serum concentration of Bromocriptine can be increased when it is combined with Clindamycin.

Cabazitaxel

Major

The metabolism of Cabazitaxel can be decreased when combined with Clindamycin.

Cabergoline

Major

The serum concentration of Cabergoline can be increased when it is combined with Clindamycin.

Clindagel Toxicity & Overdose Risk

The most toxic dose of clindamycin in mice and rats is 2540mg/kg in mice and 2190mg/kg in rats. No cases of overdose have been reported, but common symptoms may include abdominal pain, nausea, vomiting, and diarrhea. One 3-year-old child was given a large dose of clindamycin and experienced mild abdominal pain and diarrhea. Activated charcoal may be used to help remove unabsorbed drug from the body. Hemodialysis and peritoneal dialysis are not effective for this purpose. In cases of clindamycin overdose, general supportive measures should be taken.

image of a doctor in a lab doing drug, clinical research

Clindagel Novel Uses: Which Conditions Have a Clinical Trial Featuring Clindagel?

73 active clinical trials are currently assessing Clindagel as a potential therapeutic option for patients suffering from Bacterial Endocarditis, Acne and Pneumocystis Jirovecii Pneumonia.

Condition

Clinical Trials

Trial Phases

Respiratory Tract Infections (RTI) caused by susceptible streptococci

0 Actively Recruiting

Acne Vulgaris

2 Actively Recruiting

Phase 1, Phase 2, Early Phase 1

Mitral Valve Prolapse

1 Actively Recruiting

Not Applicable

Hypertrophic Cardiomyopathy

5 Actively Recruiting

Phase 2, Phase 3, Not Applicable, Phase 1

Surgically constructed systemic-pulmonary shunt

0 Actively Recruiting

Respiratory Tract Infections

0 Actively Recruiting

Bacteria, Anaerobic

0 Actively Recruiting

Heart Defects, Congenital

0 Actively Recruiting

Communicable Diseases

0 Actively Recruiting

Bone and Bones

0 Actively Recruiting

Babesiosis

1 Actively Recruiting

Phase 2

Mixed Vaginal Infections

0 Actively Recruiting

Toxoplasmosis

1 Actively Recruiting

Phase 4

Surgical Intervention

0 Actively Recruiting

Pelvic cellulitis caused by Anaerobic Bacterial Infection

0 Actively Recruiting

Bacterial Endocarditis

0 Actively Recruiting

Malaria

0 Actively Recruiting

Acne Vulgaris

0 Actively Recruiting

Vaginal Infections

0 Actively Recruiting

Acquired Immunodeficiency Syndrome

4 Actively Recruiting

Phase 1, Phase 2, Not Applicable

Clindagel Reviews: What are patients saying about Clindagel?

5

Patient Review

11/19/2012

Clindagel for Acne

I'm very pleased with the results I've seen from using clindagel in the mornings and epiduo at night. My cystic acne has improved significantly and I would recommend this combination of medications to anyone else suffering from similar skin issues. The only downside is that my skin has become quite sensitive from the medication, so I have to be careful not to use too much or it will start to look red.

4

Patient Review

10/20/2008

Clindagel for Acne Rosacea

This medication has caused my hair to become thinner.

3.3

Patient Review

4/6/2009

Clindagel for Acne

I've been using this for a couple months to help with my acne. While it does seem to cut down on the active pimples, it seems to make the scars more visible. Additionally, I developed dandruff from using this product - which was an annoying and frustrating side-effect. All in all, I'm not sure how much longer I'll be using this treatment.

3.3

Patient Review

2/2/2015

Clindagel for Acne

Although this gel reduces the swelling of my cystic acne overnight, by the next afternoon the cyst is swollen and painful once again.

3

Patient Review

10/28/2008

Clindagel for Acne

I don't think this medication should be used by teenagers. It made my acne worse and had other negative effects on my skin.

1

Patient Review

4/28/2008

Clindagel for Skin Infection due to a Bacteria

My dermatologist prescribed this to me for an inflamed blackhead. After just two days of using it as directed, my skin was so badly burned that I had to stop. Now I'm dealing with redness, blisters and peeling skin. If only I had just used aloe vera gel from the start...

Patient Q&A Section about clindagel

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is Clindagel over the counter?

"Clindagel is a prescription acne medication that can be used alone or with other medications. It is applied topically to the skin and works by reducing inflammation and killing bacteria."

Answered by AI

How much does Clindagel cost?

"The average price for the most common version of generic Clindagel is $24.27, which is 97% cheaper than the average retail price of $1,101.89."

Answered by AI

What is Clindagel used to treat?

"This acne medication decreases the number of acne lesions by stopping the growth of bacteria."

Answered by AI

How long does it take for Clindagel to work?

"Treatment of acne with Clindagel may take up to 8 to 12 weeks before full improvement is seen. If your doctor has ordered another medicine to be applied to the skin along with this medicine, it is best to apply them at different times."

Answered by AI

Clinical Trials for Clindagel

Image of Los Angeles General Medical Center in Los Angeles, United States.

Decision Support Tool for HIV Treatment

18+
All Sexes
Los Angeles, CA

This study is testing software designed to help healthcare providers choose the best HIV treatment combinations for their patients. HIV medicines, known as antiretroviral therapy (ART), can be complex to manage because the right regimen depends on many factors-such as drug resistance, other health conditions, and medication schedules. Many people with HIV are cared for by general clinicians who may not have access to HIV specialists, which can make treatment decisions more challenging. In this study, healthcare providers will use patient cases to compare standard HIV treatment resources with a new clinical decision support tool that gives evidence-based ART recommendations at the point of care. The investigators hypothesize that using the tool will help providers select treatment plans that better match clinical guidelines, make decisions faster, reduce mental effort, and increase overall satisfaction with the prescribing process.

Waitlist Available
Has No Placebo

Los Angeles General Medical Center

Hayoun Lee, PhD

Image of Keck Hospital of the University of Southern California in Los Angeles, United States.

Mitral Valve Repair Procedures for Mitral Valve Prolapse

18+
All Sexes
Los Angeles, CA

The PRIMARY trial (NCT05051033), which compares mitral valve repair (MVr) to transcatheter-edge-to-edge-repair (TEER), offers a platform for conducting mechanistic studies to develop early insights into the pathophysiological processes by which mitral valve prolapse (MVP) can impact left ventricular (LV) myocardial structure and function, and, thereby, predispose to arrhythmias and sudden death. Such insights are key to identifying interventions to reduce the long-term sequelae of heart failure (HF) and arrhythmias, as well as delineate optimal therapeutic approaches for different patient sub-groups.

Recruiting
Has No Placebo

Keck Hospital of the University of Southern California (+15 Sites)

Joanna Chikwe, MD

Image of Montefiore Medical Center in Bronx, United States.

myPACE+ Algorithm for Hypertrophic Cardiomyopathy

18+
All Sexes
Bronx, NY

This will be a two-arm investigator-initiated randomized controlled study of patients with nHCM and LV ejection fraction ≥50% and NYHA II-III symptoms, normal intrinsic conduction system and pre-existing suitable dual-chamber implantable cardioverter defibrillators (ICD) systems. Patients will be randomly assigned to either personalized accelerated pacing (using the myPACE+ algorithm with mono-fractional exponent) or usual care groups. At baseline and after 3 months of pacing all patients will undergo a CPET, echocardiogram, blood work for NT-proBNP levels and complete the KCCQ-OSS and HCMSQ, questionnaires. The investigator team hypothesizes that personalized accelerated pacing will be safe and improve symptoms and heart-failure related quality of life, physical activity, pVO2, biomarkers (i.e. NT-proBNP), diastolic parameters and cardiac structure.

Recruiting
Has No Placebo

Montefiore Medical Center (+1 Sites)

Sandhya Murthy, MD

Medtronic

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We made a collection of clinical trials featuring Clindagel, we think they might fit your search criteria.
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Image of Texas Tech University Health Sciences Center in Lubbock, United States.

Amoxicillin Challenge for Penicillin Allergy

18 - 89
All Sexes
Lubbock, TX

The goal of this clinical trial is to learn about dosing when testing to see if a penicillin allergy label can be removed from adults that had been labeled as "penicillin-allergic" previously. The main question it aims to answer is: \- In penicillin-allergic patients that are at low risk of having an allergic reaction, is a one-dose oral challenge with amoxicillin (a penicillin-based antibiotic) as safe and effective as a two-dose oral challenge? Participants will, after being identified as having a low-risk penicillin allergy, be administered oral amoxicillin in a controlled setting and then monitored for an allergic reaction. Researchers will compare participants that took one dose of amoxicillin to participants that took two doses of amoxicillin (a small dose and then a larger dose) to see if either group was more likely to develop an allergic reaction.

Phase 3
Recruiting

Texas Tech University Health Sciences Center

James A Tarbox, MD

Image of Medical University of South Carolina in Charleston, United States.

Isotretinoin vs Tetracycline for Acne

Any Age
All Sexes
Charleston, SC

In the effort to find better treatments for Moderate Acne, which often relies on long-term antibiotic use, researchers are exploring alternative options. While Isotretinoin, a Vitamin A derivative, is highly effective for severe acne, its side effects limit its use for milder cases. A recent study from our institution investigated a new approach: weekly Isotretinoin dosing. The results were promising, with acne improvement and no major side effects. This suggests that weekly Isotretinoin could be a successful alternative for moderate acne in both males and females. To validate these findings, investigators propose a randomized controlled trial comparing weekly Isotretinoin to daily Doxycycline over four months. This study could confirm the safety and effectiveness of weekly Isotretinoin, as well as shed light on patient satisfaction, and long-term results compared to standard antibiotics. This research may offer a breakthrough in treating moderate acne while addressing concerns about antibiotic overuse.

Phase < 1
Recruiting

Medical University of South Carolina

Alex Richmond, MD, MSCR

Have you considered Clindagel clinical trials?

We made a collection of clinical trials featuring Clindagel, we think they might fit your search criteria.
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Image of University of California - San Francisco in San Francisco, United States.

Exercise Program for Hypertrophic Cardiomyopathy

18 - 80
All Sexes
San Francisco, CA

The EXCITE-HCM study is a randomized, controlled, blinded clinical trial designed to evaluate the effect of moderate intensity exercise training versus usual physicial activity on the improvement of HCM-related symptoms and cardiac function. About 70 participants will be recruited and randomized on a 1:1 ratio to either moderate intensity training or usual physicial activity interventions. Patients will be followed during a period of 24 weeks and assesesments as physical examination, questionnaires, 12 lead ecg's, biomarker levels, echocardiogram, Cardiac Magnetic resonance, PET and CPET will be performed to evaluate their response to the intervention.

Recruiting
Has No Placebo

University of California - San Francisco

Theodore P Abraham, M.D

Image of Rush University Medical Center in Chicago, United States.

Menstrual Cups for Vaginal Infections

15 - 35
Female
Chicago, IL

HIV remains a global pandemic with 37 million infected. In western Kenya, 16% of women in the general population and 29% of the poorest women have HIV. The HIV and sexually transmitted infection (STI) epidemics overlap with broader reproductive health concerns. Menstrual hygiene management is a big problem in low- and middle-income countries and a lack of menstrual products negatively impacts women's work-life. This comes from cultural taboos, stigma, and discrimination, promoting secrecy around menstruation, high cost of menstrual products, use of traditional materials (e.g. rags, cotton wool, etc.) causing leakage and odor, and lack of water and safe hygiene facilities. Menstrual cups designed for use during sex may help women prevent Bacterial vaginosis (BV) and STIs through hygienic period practices, and may help them avoid bad practices in an attempt to maintain vaginal dryness. The goal of this interventional trial is to test the impact of menstrual cups on vaginal microbiome, BV, and STIs of poor women at high risk for STIs and HIV. We predict to see 25% less BV, our primary outcome, over one year. This trial aims to learn more about the safety of the intervention, and understand what is needed to fully implement the program.

Phase 2
Waitlist Available

Rush University Medical Center

Image of Columbia University Irving Medical Center in New York, United States.

WiseApp for HIV

18+
All Sexes
New York, NY

This study aims to conduct a 12-month randomized controlled trial to adapt the mobile app, WiseApp, and a smart pill dispenser for Spanish-speaking people living with HIV (PLWH) in the New York City (NYC) area and La Romana, Dominican Republic (DR). The study will assess the efficacy and sustainability of WiseApp as well as identify barriers with its widespread use among Spanish speakers. With disproportionately high rates of HIV in the New York City area and the Dominican Republic, this project seeks to identify distinct contextual factors related to Spanish speaking people living with HIV and increase the likelihood of engagement with technology and improvements in clinical outcomes.

Recruiting
Has No Placebo

Columbia University Irving Medical Center

Rebecca Schnall, PhD, MPH

Image of McGill University Health Centre (Royal Victoria Hospital and Montreal General Hospital) in Montreal, Canada.

Low-Dose Trimethoprim-Sulfamethoxazole for Pneumocystis Pneumonia

18 - 100
All Sexes
Montreal, Canada

Pneumocystis jirovecii pneumonia (PJP) is an opportunistic fungal infection of immunocompromised hosts which causes in significant morbidity and mortality. The current standard of care, trimethoprim-sulfamethoxazole (TMP-SMX) at a dose of 15-20 mg/kg/day of TMP, is associated with serious adverse events, including hypersensitivity reactions, drug-induced liver injury, cytopenia, and renal failure occurring among 20-60% of patients. The frequency of adverse events increases in a dose dependent manner and commonly limits the use of TMP-SMX. Reduced treatment doses of TMP-SMX for PJP reduced ADEs without mortality differences in a recent meta-analysis of observational studies. We therefore propose a Phase III randomized, placebo-controlled trial to directly compare the efficacy and safety of low dose (10 mg/kg/day of TMP) compared to the standard-of-care (15 mg/kg/day) among patients with PJP for the primary outcome of death, new mechanical ventilation, and change of treatment.

Phase 3
Waitlist Available

McGill University Health Centre (Royal Victoria Hospital and Montreal General Hospital)

Emily G McDonald, MD MSc

Have you considered Clindagel clinical trials?

We made a collection of clinical trials featuring Clindagel, we think they might fit your search criteria.
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