Citalopram Hydrobromide

Premature Ejaculation, Bulimia Nervosa, Panic Disorder + 7 more
Treatment
1 FDA approval
20 Active Studies for Citalopram Hydrobromide

What is Citalopram Hydrobromide

CitalopramThe Generic name of this drug
Treatment SummaryCitalopram is an antidepressant medication that belongs to a class of drugs known as selective serotonin reuptake inhibitors (SSRIs). It is commonly used to treat depression and is available in tablet and solution forms. Citalopram was first approved by the FDA in 1998 under the brand name Celexa.
Celexais the brand name
image of different drug pills on a surface
Citalopram Hydrobromide Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Celexa
Citalopram
1998
424

Approved as Treatment by the FDA

Citalopram, also known as Celexa, is approved by the FDA for 1 uses like Depression .
Depression
Helps manage Depression

Effectiveness

How Citalopram Hydrobromide Affects PatientsCitalopram is a type of antidepressant that helps to manage symptoms of depression, anxiety, eating disorders, and obsessive-compulsive disorder. It works by blocking the uptake of serotonin, a chemical in the brain responsible for regulating mood, behavior, reward, and other functions. It usually takes 1-4 weeks for citalopram to start working and 8-12 weeks for the full effects to be felt. In addition to blocking serotonin uptake, citalopram can also reduce the number of norepinephrine receptors in the brain. It does not affect monoamine oxidase.
How Citalopram Hydrobromide works in the bodyCitalopram works by blocking the reuptake of serotonin in the brain. It does this by targeting a specific protein, the serotonin transporter, to stop it from taking serotonin out of the synapse. Citalopram does not have a strong effect on other types of receptors, so it does not cause some of the side effects seen with other antidepressant drugs.

When to interrupt dosage

The prescribed dosage of Citalopram Hydrobromide is contingent upon the specified condition, such as Obsessive-Compulsive Disorder, Premenstrual Dysphoric Disorder and Diabetic Neuropathy. The quantity of dosage fluctuates, depending on the technique of delivery (e.g. Tablet - Oral or Tablet) featured in the table beneath.
Condition
Dosage
Administration
Obsessive-Compulsive Disorder
, 20.0 mg, 40.0 mg, 10.0 mg, 10.0 mg/mL, 0.4 mg, 30.0 mg, 2.0 mg/mL
, Oral, Tablet, Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral, Solution, Solution - Oral, Kit, Capsule, Capsule - Oral
Social Anxiety Disorder
, 20.0 mg, 40.0 mg, 10.0 mg, 10.0 mg/mL, 0.4 mg, 30.0 mg, 2.0 mg/mL
, Oral, Tablet, Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral, Solution, Solution - Oral, Kit, Capsule, Capsule - Oral
Generalized Anxiety Disorder
, 20.0 mg, 40.0 mg, 10.0 mg, 10.0 mg/mL, 0.4 mg, 30.0 mg, 2.0 mg/mL
, Oral, Tablet, Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral, Solution, Solution - Oral, Kit, Capsule, Capsule - Oral
Diabetic Neuropathy
, 20.0 mg, 40.0 mg, 10.0 mg, 10.0 mg/mL, 0.4 mg, 30.0 mg, 2.0 mg/mL
, Oral, Tablet, Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral, Solution, Solution - Oral, Kit, Capsule, Capsule - Oral
Anorexia Nervosa
, 20.0 mg, 40.0 mg, 10.0 mg, 10.0 mg/mL, 0.4 mg, 30.0 mg, 2.0 mg/mL
, Oral, Tablet, Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral, Solution, Solution - Oral, Kit, Capsule, Capsule - Oral
Premature Ejaculation
, 20.0 mg, 40.0 mg, 10.0 mg, 10.0 mg/mL, 0.4 mg, 30.0 mg, 2.0 mg/mL
, Oral, Tablet, Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral, Solution, Solution - Oral, Kit, Capsule, Capsule - Oral
Post Traumatic Stress Disorder
, 20.0 mg, 40.0 mg, 10.0 mg, 10.0 mg/mL, 0.4 mg, 30.0 mg, 2.0 mg/mL
, Oral, Tablet, Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral, Solution, Solution - Oral, Kit, Capsule, Capsule - Oral
Bulimia Nervosa
, 20.0 mg, 40.0 mg, 10.0 mg, 10.0 mg/mL, 0.4 mg, 30.0 mg, 2.0 mg/mL
, Oral, Tablet, Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral, Solution, Solution - Oral, Kit, Capsule, Capsule - Oral
Depression
, 20.0 mg, 40.0 mg, 10.0 mg, 10.0 mg/mL, 0.4 mg, 30.0 mg, 2.0 mg/mL
, Oral, Tablet, Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral, Solution, Solution - Oral, Kit, Capsule, Capsule - Oral
Panic Disorder
, 20.0 mg, 40.0 mg, 10.0 mg, 10.0 mg/mL, 0.4 mg, 30.0 mg, 2.0 mg/mL
, Oral, Tablet, Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral, Solution, Solution - Oral, Kit, Capsule, Capsule - Oral

Warnings

Citalopram Hydrobromide has three contraindications and should not be employed together with the circumstances detailed in the subsequent table.Citalopram Hydrobromide Contraindications
Condition
Risk Level
Notes
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Citalopram may interact with Pulse Frequency
There are 20 known major drug interactions with Citalopram Hydrobromide.
Common Citalopram Hydrobromide Drug Interactions
Drug Name
Risk Level
Description
Abemaciclib
Major
The metabolism of Abemaciclib can be decreased when combined with Citalopram.
Acalabrutinib
Major
The metabolism of Acalabrutinib can be decreased when combined with Citalopram.
Alectinib
Major
The metabolism of Alectinib can be decreased when combined with Citalopram.
Aminophylline
Major
The metabolism of Aminophylline can be decreased when combined with Citalopram.
Amoxapine
Major
The metabolism of Amoxapine can be decreased when combined with Citalopram.
Citalopram Hydrobromide Toxicity & Overdose RiskThe toxic dose of citalopram in humans is 56mg/kg and 179 mg/kg in mice. Symptoms of overdose include dizziness, sweating, nausea, vomiting, trembling, sleepiness, and an increased heart rate. In rare cases, symptoms may include amnesia, confusion, coma, seizures, shallow breathing, and a bluish skin color. If someone overdoses on citalopram, medical professionals should ensure the person is breathing properly and monitored for changes in their heart rate and other vital signs. Treatments for citalopram overdose include lavage and activated charcoal, however dialysis and other forms of filtering are
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Citalopram Hydrobromide Novel Uses: Which Conditions Have a Clinical Trial Featuring Citalopram Hydrobromide?

954 active clinical trials are investigating the potential of Citalopram Hydrobromide to alleviate Panic Disorder, Obsessive-Compulsive Disorder and Depression.
Condition
Clinical Trials
Trial Phases
Obsessive-Compulsive Disorder
66 Actively Recruiting
Not Applicable, Phase 2, Phase 3, Phase 1, Early Phase 1
Post Traumatic Stress Disorder
236 Actively Recruiting
Not Applicable, Early Phase 1, Phase 3, Phase 4, Phase 2, Phase 1
Panic Disorder
13 Actively Recruiting
Not Applicable
Bulimia Nervosa
0 Actively Recruiting
Depression
300 Actively Recruiting
Not Applicable, Phase 1, Phase 2, Early Phase 1, Phase 4, Phase 3
Premature Ejaculation
0 Actively Recruiting
Diabetic Neuropathy
5 Actively Recruiting
Not Applicable, Phase 1, Phase 2
Social Anxiety Disorder
15 Actively Recruiting
Not Applicable
Anorexia Nervosa
0 Actively Recruiting
Generalized Anxiety Disorder
7 Actively Recruiting
Not Applicable, Phase 2, Phase 3

Citalopram Hydrobromide Reviews: What are patients saying about Citalopram Hydrobromide?

5Patient Review
6/29/2022
Citalopram Hydrobromide for Depression
I've been taking citalopram for four months now, and they're really working well for me. I had a few side effects at first that made me feel nauseous, but my doctor suggested taking them with my evening meal and that solved the problem. Now I'm able to sleep and go to work again without any issues.
4.3Patient Review
3/17/2022
Citalopram Hydrobromide for "Change of Life" Signs
I used this treatment four years ago and it was effective.
4Patient Review
3/22/2022
Citalopram Hydrobromide for Depression
This treatment really helped to get my emotions under control. I would highly recommend it for anyone struggling with sadness or anger.
4Patient Review
6/2/2022
Citalopram Hydrobromide for Major Depressive Disorder
I've dealt with depression for a long time, and this was one of the better medications I tried. No weight gain, decent sleep, and good days mixed in with the bad. The only downside is that it stopped being effective after a while.
4Patient Review
3/20/2022
Citalopram Hydrobromide for Anxiousness associated with Depression
I've been on this medication for four weeks and I have definitely noticed an improvement in my mood. That being said, I have also experienced some side effects like dizziness and headaches.
2.7Patient Review
3/11/2022
Citalopram Hydrobromide for Depression
I didn't find this medication effective at all and actually felt worse after taking it. The side effects were also pretty bad; I was constantly tired and had panic attacks.
2.3Patient Review
4/29/2022
Citalopram Hydrobromide for Anxiousness associated with Depression
I don't think these work as well as people say they do.
1Patient Review
9/24/2022
Citalopram Hydrobromide for Panic Disorder
I felt like this medication was burning me from the inside out. I had terrible tremors, shaking, and muscle aches. This also made my anxiety much worse and I felt constantly cold and shivering.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about citalopram hydrobromide

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is Xanax the same as citalopram?

"Celexa and Xanax are not the same medication, even though you might experience some of the same side effects while taking them. Celexa is a selective serotonin reuptake inhibitor (SSRI), while Xanax is a benzodiazepine."

Answered by AI

What are citalopram hydrobromide used for?

"Citalopram is used as an antidepressant to treat major depressive disorder by increasing serotonin activity in the brain."

Answered by AI

Is citalopram hydrobromide for anxiety?

"Celexa is a selective serotonin reuptake inhibitor (SSRI) and Xanax is a benzodiazepine.

Celexa works by increasing the level of serotonin in the brain while Xanax works by affecting certain chemicals in the brain that may become unbalanced and cause anxiety."

Answered by AI

What are the most common side effects of citalopram?

"The following effects may occur: nausea, dry mouth, loss of appetite, tiredness, drowsiness, sweating, blurred vision, and yawning. If you experience any of these effects for an extended period of time, or if they worsen, consult your doctor or pharmacist."

Answered by AI

Clinical Trials for Citalopram Hydrobromide

Image of Cedars-Sinai Medical Center in Los Angeles, United States.

Living Well Program for Anxiety in Breast Cancer

18+
Female
Los Angeles, CA
The goal of this study is to evaluate the efficacy and cost-effectiveness of the Living Well Program, a digital therapeutic application with telecoaching support, in breast cancer patients with moderate-to-severe anxiety. The main question the study aims to answer is: does digital cognitive-behavioral therapy-based interventions decrease the overall healthcare costs of patients with stage II to IV breast cancer? The study has one group of participants who will use the Living Well app and telecoaching support. This group will be compared to retroactively matched controls. Over 3 months, patients will complete 21 mental health modules and 5 telecoaching sessions. In the following 3 months, they will complete any outstanding telecoaching sessions and modules while still being monitored, even if they finished all modules and sessions in the first 3 months. The 6 months after that will be the follow-up phase. They will still have access to the Living Well app and may continue to use it, and they will complete the same assessment questionnaires as baseline to identify any changes in their overall mental health.
Waitlist Available
Has No Placebo
Cedars-Sinai Medical CenterScott Irwin, MD
Image of Baylor College of Medicine in Houston, United States.

Stepped Care Treatment for Anxiety

7 - 17
All Sexes
Houston, TX
Childhood anxiety disorders (CAD) are common and impairing. Family based cognitive behavioral therapy (CBT) is efficacious in treating CAD. Yet, many children do not receive care due to barriers such as limited provider availably, high treatment costs, and constrained family resources (e.g., time). To combat these barriers, other treatment methods have been developed. The stepped care treatment models maximize resources by providing low-intensity, low-cost interventions as a first time treatment, while stepping up care for those needing more intensive treatment. Specifically, a stepped care model for CAD that begins with a parent-focus intervention has great promise to deliver efficacious and cost-effective treatment without having to engage the child. While stepped care approaches show promise in treating CAD with comparable efficacy to standard CBT, there remains a large research-to-practice gap. The stepped care model for CAD that begins with a parent-focused intervention has yet been explored, and very little is known about intervention mediators that explain mechanisms of change. This research is being done to improve the reach and quality of services using a stepped care model, offering an affordable and practical solution to the widespread gap in youth mental health care.
Waitlist Available
Has No Placebo
Baylor College of Medicine
Image of Duke University School of Medicine in Durham, United States.

Cognitive Rehabilitation for Anger in TBI and PTSD

18+
All Sexes
Durham, NC
This randomized clinical trial will enroll 100 Veteran-family/friend dyads to test the efficacy of CALM in treating anger in TBI and PTSD. The investigators hypothesize that compared to an active control group, Veterans randomized to the CALM group will demonstrate: * Significantly larger decreases in anger dysregulation, impulsivity, and executive dysfunction. * Significantly larger improvements in social and adaptive functioning including less aggression. * Significantly larger reduction in PTSD symptoms and suicidal ideation. The study targets Veterans who experience difficulties with anger and impulsivity due to TBI and PTSD. These issues are common, with up to 38% of Veterans with TBI also having PTSD. These conditions often make it challenging for Veterans to control their emotions and interact successfully in social and work settings. Our research will test the CALM (Cognitive Applications for Life Management) mobile app, which helps Veterans manage their goals, remember important tasks, and improve their attention. Initial tests of CALM have shown it can reduce levels of anger and related issues in Veterans. The investigators will conduct a study with 100 pairings of Veterans and a family member or friend. These pairs will be randomly assigned to one of two groups: one using the CALM mobile platform and the other receiving brain health education. Both groups will use their assigned intervention for three months and will receive support through videoconference calls at the beginning, middle, and end of the program.
Waitlist Available
Has No Placebo
Duke University School of MedicineEric Elbogen
Have you considered Citalopram Hydrobromide clinical trials? We made a collection of clinical trials featuring Citalopram Hydrobromide, we think they might fit your search criteria.Go to Trials
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Inhaled Cannabis for PTSD

18+
All Sexes
Cave Creek, AZ
The rationale for the use of inhalational cannabis to potentially treat PTSD symptoms is based on the many reports of cannabis attenuating PTSD symptom expression among individuals with PTSD, including veterans. Study MJP2 is intended to build off MJP-1 through use of a larger sample size, a parallel study design, and subjective bias mitigation methods to re-examine the use of inhaled high THC-containing cannabis versus placebo for management of PTSD symptoms in a U.S. Veteran sample. Together these studies are intended to provide valuable insights on the already widespread use of cannabis in individuals with PTSD, for which there is currently a lack of controlled evidence available reflective of this real-world use.
Phase 2
Waitlist Available
Scottsdale Research Institute
Image of University of California San Diego in La Jolla, United States.

AI Chatbot for Postpartum Loneliness

18+
Female
La Jolla, CA
The goal of this clinical trial is to learn whether a postpartum chatbot powered by generative artificial intelligence (genAI) can help new mothers get better pelvic floor health information and feel less lonely after childbirth. The main questions this study aims to answer are: * Does using the chatbot improve postpartum pelvic floor health knowledge? * Does using the chatbot help reduce feelings of loneliness during the postpartum period? * Does using the chatbot impact pelvic floor symptoms? Researchers will compare standard postpartum care to standard care plus the chatbot. Participants will: Be assigned by chance (like flipping a coin) to standard postpartum care with or without access to the chatbot. If in the chatbot group, participants will receive education and support via the chatbot over a 4-week period. Both groups will complete questionnaires to measure their pelvic floor knowledge, pelvic floor symptoms, feelings of loneliness, depression, infant bonding, perceived social support, adverse childhood experiences, and peri-traumatic distress. The chatbot was created by urogynecology experts in collaboration with UC San Diego computer science and biomedical informatics researchers. The chatbot is designed to give new mothers personalized, evidence-based information and support in real time.
Waitlist Available
Has No Placebo
University of California San Diego
Image of Mayo Clinic in Florida in Jacksonville, United States.

Virtual Reality for Cancer

18 - 90
All Sexes
Jacksonville, FL
This clinical trial tests the safety, tolerability, and effectiveness of a virtual reality intervention to improve psychological symptom burden for cancer patients undergoing treatment. Virtual reality (VR) is a technology that allows users to experience and interact with three-dimensional, computer-generated environments that simulate the real world or imagined settings. The VR intervention consists of a preloaded with immersive environments designed to engage the senses through simulated sights and sounds. This may include a walk through of a serene forest, exploring vibrant coral reefs, swimming with dolphins, or standing at the base of a majestic waterfall. These environments are created to provide a relaxing and engaging experience. Completing the VR intervention may be a safe and effective way to improve quality of life, reduce anxiety, enhance focus, and promote healthy living for cancer patients undergoing treatment.
Recruiting
Has No Placebo
Mayo Clinic in FloridaJuan C. Cardenas Rosales, MD
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Integrated Health Care for Post-Traumatic Stress Disorder

18+
All Sexes
Phoenix, AZ
The goal of this clinical trial is to determine whether which types of integrative care, meaning a combination of psychotherapy and mind-body interventions, lead to the most changes in functioning among Veterans with posttraumatic stress disorder (PTSD). The main aims are: 1. To evaluate the impact of integrative care approaches on functional outcomes among Veterans with PTSD. 2. To examine factors relevant to the implementation of integrated treatments for PTSD from the perspective of patients, providers and administrators in the VA Healthcare System. Participants will: 1. Complete assessments at the beginning of the study and 12- and 24-weeks later. 2. Engage in 12 weeks of integrated care, with the type being randomly assigned.
Waitlist Available
Has No Placebo
VA Phoenix Healthcare System (+4 Sites)
Have you considered Citalopram Hydrobromide clinical trials? We made a collection of clinical trials featuring Citalopram Hydrobromide, we think they might fit your search criteria.Go to Trials
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Akashic Records Sessions for Mental Health

18+
All Sexes
Palm City, FL
The goal of this clinical study is to learn the impact of two Akashic Records sessions on mental health symptoms in adults. We want to see how sessions are linked to stress, anxiety, and depression, and to resilience (ability to bounce back) and feelings of connectedness (to self, community, and humanity). Main questions this study will answer are: After two sessions, what is the impact on stress, anxiety, and depression? After two sessions, what is the impact on resilience and connectedness? How do participants describe their experience of the sessions? After two sessions, what are participants' views of their problems (insight), emotional experiences (impact) and observable behaviors in their daily life? What participants will do: Complete online surveys about their mood at four points: before the first session, before the second session, after the second session, and again 2 months later. Surveys include: DASS-21 (Depression, Anxiety, and Stress Scale) CD-RISC-10 (Connor-Davidson Resilience Scale) WATTS (Connectedness Scale) A short demographic form and satisfaction survey Attend two individual Akashic Records sessions (50-90 minutes each) over private video platform with a licensed clinical social worker (principal investigator) The first 50 participants will also join a one-hour interview with open ended questions with a licensed clinical social worker (co-investigator) about one week after the second session to share their experience in their own words. Who can take part: Adults ages 18 and older who can read and consent in English and who have experienced stress, anxiety, or low mood in the past year. How the research will happen: Sessions are held by secure video call. Participants will also complete private online surveys before, during, and after the sessions. Some participants may be invited to share their experiences in a one-on-one interview. All information is kept private and names are removed before analysis. Risks and benefits: Talking about personal topics may bring up strong emotions. Licensed clinicians conduct sessions, offer support, and provide referrals if needed. Possible benefits include new insights, greater peace or meaning, and improved coping; benefits are not guaranteed. Why this matters: Many people seek spiritual or transpersonal support for emotional concerns. This pilot study will provide early evidence on whether Akashic Records sessions may be a helpful, low-risk option and will guide future research.
Waitlist Available
Has No Placebo
Virtual/ No Physical FacilityCandice S Rasa, LCSW
Image of University of California, Los Angeles in Los Angeles, United States.

Virtual Reality Reward Training for Depression

18+
All Sexes
Los Angeles, CA
The purpose of this study is to compare the effects of enhanced Virtual Reality-Reward Training (eVR-RT) with an active control condition, Virtual Reality-Memory Training (VR-MT), on positive affect and other clinical symptoms. Enhanced VR-Reward Training is a novel intervention aimed at enhancing savoring of positive experiences among individuals with depression and low positive affect through guided imaginal recounting following immersion in positive VR experiences. The current study tests an enhanced version of this training using improved virtual reality technology. Target enrollment is 80 participants with low positive affect, depression, and impaired functioning, who are at least 18 years old, who will be randomly assigned to 7 weeks of either enhanced Virtual Reality-Reward Training (VR-RT) or Virtual Reality-Memory Training (VR-MT). Participants will complete in-person VR sessions, laboratory assessments, self-report questionnaires as part of the study. A subset of 8 participants randomly assigned to VR-RT will complete fMRI scans and EMA surveys. The total length of participation is around 3 months.
Phase 2
Recruiting
University of California, Los Angeles
Have you considered Citalopram Hydrobromide clinical trials? We made a collection of clinical trials featuring Citalopram Hydrobromide, we think they might fit your search criteria.Go to Trials
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