Centany

Impetigo, Communicable Diseases, staphylococcus aurea colonization of the nasal passage + 3 more

Treatment

7 FDA approvals

0 Active Studies for Centany

What is Centany

Mupirocin

The Generic name of this drug

Treatment Summary

Mupirocin is a type of antibiotic that works differently than other antibiotics. It is made naturally by the organism Pseudomonas fluorescens and is used to treat impetigo, a bacterial skin infection caused by Staphylococcus aureus and Streptococcus pyogenes, as well as other secondary bacterial skin infections. It is also sometimes used to treat nasal carriage of Staphylococci when administered intranasally. Mupirocin is only available in topical forms and is sold under the brand name Bactroban.

Bactroban

is the brand name

image of different drug pills on a surface

Centany Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Bactroban

Mupirocin

1996

98

Approved as Treatment by the FDA

Mupirocin, also called Bactroban, is approved by the FDA for 7 uses which include staphylococcus aurea colonization of the nasal passage and Secondary infection Skin infection .

staphylococcus aurea colonization of the nasal passage

Secondary infection Skin infection

Bacterial infection due to streptococcus, group A

Impetigo

Bacterial Infections

Impetigo

Communicable Diseases

Effectiveness

How Centany Affects Patients

Mupirocin can be used to treat many different types of bacterial infections, such as staphylococcus aureus and streptococcus pyogenes. It works by preventing bacteria from making proteins needed for them to survive. Tests have found that it is effective in over 90% of patients with skin infections, but it can develop resistance in some cases. Resistance is more common in staphylococci that are resistant to other antibiotics.

How Centany works in the body

Mupirocin works by interrupting the production of proteins and RNA in bacteria. It binds to a specific enzyme that helps convert isoleucine and tRNA into isoleucyl-tRNA. By blocking this enzyme, mupirocin stops bacteria from producing proteins and RNA. At lower concentrations, mupirocin stops bacteria from growing, while at higher concentrations it can actually kill up to 99% of susceptible bacteria in 24 hours.

When to interrupt dosage

The proposed dose of Centany is contingent upon the diagnosed state, such as Communicable Diseases, Bacterial Infections and staphylococcus aurea colonization of the nasal passage. The measure of dosage is contingent upon the process of delivery (e.g. Ointment or Cream) delineated in the table below.

Condition

Dosage

Administration

staphylococcus aurea colonization of the nasal passage

0.02 mg/mg, , 0.0215 mg/mg, 2.0 %

, Topical, Ointment - Topical, Cream, Cream - Topical, Ointment, Nasal, Ointment - Nasal, Kit - Topical, Kit

Impetigo

0.02 mg/mg, , 0.0215 mg/mg, 2.0 %

, Topical, Ointment - Topical, Cream, Cream - Topical, Ointment, Nasal, Ointment - Nasal, Kit - Topical, Kit

Impetigo

0.02 mg/mg, , 0.0215 mg/mg, 2.0 %

, Topical, Ointment - Topical, Cream, Cream - Topical, Ointment, Nasal, Ointment - Nasal, Kit - Topical, Kit

Communicable Diseases

0.02 mg/mg, , 0.0215 mg/mg, 2.0 %

, Topical, Ointment - Topical, Cream, Cream - Topical, Ointment, Nasal, Ointment - Nasal, Kit - Topical, Kit

Impetigo

0.02 mg/mg, , 0.0215 mg/mg, 2.0 %

, Topical, Ointment - Topical, Cream, Cream - Topical, Ointment, Nasal, Ointment - Nasal, Kit - Topical, Kit

Bacterial Infections

0.02 mg/mg, , 0.0215 mg/mg, 2.0 %

, Topical, Ointment - Topical, Cream, Cream - Topical, Ointment, Nasal, Ointment - Nasal, Kit - Topical, Kit

Warnings

Centany Contraindications

Condition

Risk Level

Notes

Severe Hypersensitivity Reactions

Do Not Combine

Mupirocin may interact with Pulse Frequency

There are 16 known major drug interactions with Centany.

Common Centany Drug Interactions

Drug Name

Risk Level

Description

Vibrio cholerae CVD 103-HgR strain live antigen

Major

The therapeutic efficacy of Vibrio cholerae CVD 103-HgR strain live antigen can be decreased when used in combination with Mupirocin.

(R)-warfarin

Moderate

The risk or severity of bleeding can be increased when Mupirocin is combined with (R)-warfarin.

(S)-Warfarin

Moderate

The risk or severity of bleeding can be increased when Mupirocin is combined with (S)-Warfarin.

4-hydroxycoumarin

Moderate

The risk or severity of bleeding can be increased when Mupirocin is combined with 4-hydroxycoumarin.

Acenocoumarol

Moderate

The risk or severity of bleeding can be increased when Mupirocin is combined with Acenocoumarol.

Centany Toxicity & Overdose Risk

The maximum toxic dose of mupirocin in rats is 5000mg/kg. No studies have been done to evaluate if mupirocin can cause cancer. Tests in animals and bacteria did not show any signs of it damaging genes. In tests involving male and female rats, there were no signs that mupirocin affected their fertility. Mupirocin has been found in human milk, so it should be used cautiously in pregnant women. Clinical trials showed that mupirocin is safe and effective for children aged 2 months to 16 years old.

image of a doctor in a lab doing drug, clinical research

Centany Novel Uses: Which Conditions Have a Clinical Trial Featuring Centany?

An active clinical trial is currently underway to investigate the potential of Centany to address Bacterial Infections, Impetigo and Communicable Diseases.

Condition

Clinical Trials

Trial Phases

Bacterial Infections

0 Actively Recruiting

staphylococcus aurea colonization of the nasal passage

0 Actively Recruiting

Communicable Diseases

0 Actively Recruiting

Impetigo

0 Actively Recruiting

Impetigo

0 Actively Recruiting

Impetigo

0 Actively Recruiting

Centany Reviews: What are patients saying about Centany?

5

Patient Review

11/27/2010

Centany for Methicillin-Resistant Staphylococcus Aureus Bacteria in Nose

My dermatologist prescribed me this medication to help with a boil I had. After just one week of use, the infection was gone and there was barely any swelling or redness. I later learned from the doctor that the medication is great at killing bacteria.

5

Patient Review

9/5/2015

Centany for Minor Skin Infection caused by Bacteria

I've found this to be an effective medication, especially when applied several times throughout the day with a light bandage.

5

Patient Review

9/23/2007

Centany for Inflammation of a Hair Follicle

5

Patient Review

9/28/2010

Centany for Presence of Boils On the Skin

image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about centany

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What does mupirocin do to bacteria?

"Mupirocin is unique among antibiotics in that it inhibits the activity of isoleucyl-tRNA synthetase, an enzyme required for bacterial protein synthesis. Without this enzyme, bacteria are unable to produce proteins and ultimately die."

Answered by AI

What is Centany used for?

"Mupirocin is a cream or ointment that is applied to the skin and is used to treat moderate to severe small skin infections. It has very few side effects."

Answered by AI

What is mupirocin used to treat?

"Mupirocin topical cream is used to treat skin lesions that have become infected with specific bacteria. Mupirocin topical ointment is used to treat impetigo. This medicine kills bacteria or prevents their growth. This medicine is only available with a doctor's prescription."

Answered by AI

Is Centany an OTC?

"Centany is a prescription medicine used to treat the symptoms of Impetigo, Secondary Skin Infection and Elimination of MRSA Colonization. Centany may be used alone or with other medications. Centany belongs to a class of drugs called Antibacterials, Topical."

Answered by AI