Cefoxitin

Endometritis, Lung Abscess, Pneumonia + 16 more
Treatment
18 FDA approvals
20 Active Studies for Cefoxitin

What is Cefoxitin

CefoxitinThe Generic name of this drug
Treatment SummaryCefoxitin is a type of antibiotic used to treat a wide range of bacterial infections. It is administered through an intravenous injection and is derived from a bacteria called Streptomyces lactamdurans.
Mefoxinis the brand name
image of different drug pills on a surface
Cefoxitin Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Mefoxin
Cefoxitin
1978
36

Approved as Treatment by the FDA

Cefoxitin, also known as Mefoxin, is approved by the FDA for 18 uses which include Septicemia and Bacterial Infections .
Septicemia
Bacterial Infections
Intraabdominal Infections
Parametritis
Influenza
Lung Abscess
Urinary tract infection
Bone and Joint Infections
Urinary Tract Infection (UTI)
Communicable Diseases
Peritonitis
surgical prophylaxis therapy
Antibiotics
Abscess, Intra-Abdominal
Endometritis
Pelvic Inflammatory Disease (PID)
Pneumonia
Bacteria

Effectiveness

How Cefoxitin Affects PatientsCefoxitin is a type of antibiotic used to treat infections caused by certain bacteria. It works against a wide range of bacteria, including anaerobic bacteria, which don't need oxygen to survive. Cefoxitin is also known to be very stable in the presence of molecules that break down other antibiotics, which helps it remain effective against certain bacteria.
How Cefoxitin works in the bodyCefoxitin kills bacteria by interfering with the production of their cell walls.

When to interrupt dosage

The proposed measure of Cefoxitin depends upon the identified ailment, including Communicable Diseases, Urinary Tract Infection (UTI) and Bacterial Infections. The amount of dosage is contingent upon the method of administration featured in the table beneath.
Condition
Dosage
Administration
Intraabdominal Infections
100.0 mg/mL, , 200.0 mg/mL, 2000.0 mg, 1000.0 mg, 10000.0 mg, 100000.0 mg
, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection, solution, Injection, solution - Intravenous, Powder, for solution, Powder, for solution - Intravenous, Intramuscular; Intravenous, Powder, for solution - Intramuscular; Intravenous
Abscess, Intra-Abdominal
100.0 mg/mL, , 200.0 mg/mL, 2000.0 mg, 1000.0 mg, 10000.0 mg, 100000.0 mg
, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection, solution, Injection, solution - Intravenous, Powder, for solution, Powder, for solution - Intravenous, Intramuscular; Intravenous, Powder, for solution - Intramuscular; Intravenous
Urinary Tract Infection (UTI)
100.0 mg/mL, , 200.0 mg/mL, 2000.0 mg, 1000.0 mg, 10000.0 mg, 100000.0 mg
, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection, solution, Injection, solution - Intravenous, Powder, for solution, Powder, for solution - Intravenous, Intramuscular; Intravenous, Powder, for solution - Intramuscular; Intravenous
Parametritis
100.0 mg/mL, , 200.0 mg/mL, 2000.0 mg, 1000.0 mg, 10000.0 mg, 100000.0 mg
, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection, solution, Injection, solution - Intravenous, Powder, for solution, Powder, for solution - Intravenous, Intramuscular; Intravenous, Powder, for solution - Intramuscular; Intravenous
Septicemia
100.0 mg/mL, , 200.0 mg/mL, 2000.0 mg, 1000.0 mg, 10000.0 mg, 100000.0 mg
, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection, solution, Injection, solution - Intravenous, Powder, for solution, Powder, for solution - Intravenous, Intramuscular; Intravenous, Powder, for solution - Intramuscular; Intravenous
Urinary tract infection
100.0 mg/mL, , 200.0 mg/mL, 2000.0 mg, 1000.0 mg, 10000.0 mg, 100000.0 mg
, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection, solution, Injection, solution - Intravenous, Powder, for solution, Powder, for solution - Intravenous, Intramuscular; Intravenous, Powder, for solution - Intramuscular; Intravenous
Bacteria
100.0 mg/mL, , 200.0 mg/mL, 2000.0 mg, 1000.0 mg, 10000.0 mg, 100000.0 mg
, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection, solution, Injection, solution - Intravenous, Powder, for solution, Powder, for solution - Intravenous, Intramuscular; Intravenous, Powder, for solution - Intramuscular; Intravenous
surgical prophylaxis therapy
100.0 mg/mL, , 200.0 mg/mL, 2000.0 mg, 1000.0 mg, 10000.0 mg, 100000.0 mg
, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection, solution, Injection, solution - Intravenous, Powder, for solution, Powder, for solution - Intravenous, Intramuscular; Intravenous, Powder, for solution - Intramuscular; Intravenous
Endometritis
100.0 mg/mL, , 200.0 mg/mL, 2000.0 mg, 1000.0 mg, 10000.0 mg, 100000.0 mg
, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection, solution, Injection, solution - Intravenous, Powder, for solution, Powder, for solution - Intravenous, Intramuscular; Intravenous, Powder, for solution - Intramuscular; Intravenous
Lung Abscess
100.0 mg/mL, , 200.0 mg/mL, 2000.0 mg, 1000.0 mg, 10000.0 mg, 100000.0 mg
, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection, solution, Injection, solution - Intravenous, Powder, for solution, Powder, for solution - Intravenous, Intramuscular; Intravenous, Powder, for solution - Intramuscular; Intravenous
Pneumonia
100.0 mg/mL, , 200.0 mg/mL, 2000.0 mg, 1000.0 mg, 10000.0 mg, 100000.0 mg
, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection, solution, Injection, solution - Intravenous, Powder, for solution, Powder, for solution - Intravenous, Intramuscular; Intravenous, Powder, for solution - Intramuscular; Intravenous
Peritonitis
100.0 mg/mL, , 200.0 mg/mL, 2000.0 mg, 1000.0 mg, 10000.0 mg, 100000.0 mg
, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection, solution, Injection, solution - Intravenous, Powder, for solution, Powder, for solution - Intravenous, Intramuscular; Intravenous, Powder, for solution - Intramuscular; Intravenous
Animal bite
100.0 mg/mL, , 200.0 mg/mL, 2000.0 mg, 1000.0 mg, 10000.0 mg, 100000.0 mg
, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection, solution, Injection, solution - Intravenous, Powder, for solution, Powder, for solution - Intravenous, Intramuscular; Intravenous, Powder, for solution - Intramuscular; Intravenous
Influenza
100.0 mg/mL, , 200.0 mg/mL, 2000.0 mg, 1000.0 mg, 10000.0 mg, 100000.0 mg
, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection, solution, Injection, solution - Intravenous, Powder, for solution, Powder, for solution - Intravenous, Intramuscular; Intravenous, Powder, for solution - Intramuscular; Intravenous
Bacterial Infections
100.0 mg/mL, , 200.0 mg/mL, 2000.0 mg, 1000.0 mg, 10000.0 mg, 100000.0 mg
, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection, solution, Injection, solution - Intravenous, Powder, for solution, Powder, for solution - Intravenous, Intramuscular; Intravenous, Powder, for solution - Intramuscular; Intravenous
Antibiotics
100.0 mg/mL, , 200.0 mg/mL, 2000.0 mg, 1000.0 mg, 10000.0 mg, 100000.0 mg
, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection, solution, Injection, solution - Intravenous, Powder, for solution, Powder, for solution - Intravenous, Intramuscular; Intravenous, Powder, for solution - Intramuscular; Intravenous
Bone and Joint Infections
100.0 mg/mL, , 200.0 mg/mL, 2000.0 mg, 1000.0 mg, 10000.0 mg, 100000.0 mg
, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection, solution, Injection, solution - Intravenous, Powder, for solution, Powder, for solution - Intravenous, Intramuscular; Intravenous, Powder, for solution - Intramuscular; Intravenous
Pelvic Inflammatory Disease (PID)
100.0 mg/mL, , 200.0 mg/mL, 2000.0 mg, 1000.0 mg, 10000.0 mg, 100000.0 mg
, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection, solution, Injection, solution - Intravenous, Powder, for solution, Powder, for solution - Intravenous, Intramuscular; Intravenous, Powder, for solution - Intramuscular; Intravenous
Communicable Diseases
100.0 mg/mL, , 200.0 mg/mL, 2000.0 mg, 1000.0 mg, 10000.0 mg, 100000.0 mg
, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection, solution, Injection, solution - Intravenous, Powder, for solution, Powder, for solution - Intravenous, Intramuscular; Intravenous, Powder, for solution - Intramuscular; Intravenous

Warnings

There are 20 known major drug interactions with Cefoxitin.
Common Cefoxitin Drug Interactions
Drug Name
Risk Level
Description
Neomycin
Major
The risk or severity of nephrotoxicity can be increased when Cefoxitin is combined with Neomycin.
Tenofovir
Major
Cefoxitin may increase the nephrotoxic activities of Tenofovir.
Tenofovir alafenamide
Major
Cefoxitin may increase the nephrotoxic activities of Tenofovir alafenamide.
Tenofovir disoproxil
Major
Cefoxitin may increase the nephrotoxic activities of Tenofovir disoproxil.
Vibrio cholerae CVD 103-HgR strain live antigen
Major
The therapeutic efficacy of Vibrio cholerae CVD 103-HgR strain live antigen can be decreased when used in combination with Cefoxitin.
Cefoxitin Toxicity & Overdose RiskThe most toxic dose of the drug in female mice and rabbits, when administered intravenously, is 8.0 g/kg and greater than 1.0 g/kg respectively. The most toxic dose in rats, when administered intraperitoneally, is greater than 10.0 g/kg.
image of a doctor in a lab doing drug, clinical research

Cefoxitin Novel Uses: Which Conditions Have a Clinical Trial Featuring Cefoxitin?

130 active clinical trials are examining the potential of Cefoxitin to alleviate Parametritis, Urinary tract infection and Endometritis.
Condition
Clinical Trials
Trial Phases
Endometritis
0 Actively Recruiting
Bone and Joint Infections
0 Actively Recruiting
Influenza
32 Actively Recruiting
Not Applicable, Phase 2, Phase 4, Phase 3, Phase 1
Communicable Diseases
0 Actively Recruiting
surgical prophylaxis therapy
0 Actively Recruiting
Septicemia
1 Actively Recruiting
Not Applicable
Antibiotics
0 Actively Recruiting
Pneumonia
62 Actively Recruiting
Phase 1, Phase 2, Not Applicable, Phase 3, Early Phase 1, Phase 4
Lung Abscess
0 Actively Recruiting
Intraabdominal Infections
3 Actively Recruiting
Not Applicable, Phase 4
Parametritis
0 Actively Recruiting
Urinary Tract Infection (UTI)
23 Actively Recruiting
Phase 2, Phase 1, Phase 4, Phase 3, Not Applicable
Bacteria
0 Actively Recruiting
Bacterial Infections
1 Actively Recruiting
Phase 4
Peritonitis
1 Actively Recruiting
Not Applicable
Pelvic Inflammatory Disease (PID)
0 Actively Recruiting
Abscess, Intra-Abdominal
0 Actively Recruiting
Animal bite
0 Actively Recruiting
Urinary tract infection
0 Actively Recruiting

Cefoxitin Reviews: What are patients saying about Cefoxitin?

3Patient Review
5/11/2013
Cefoxitin for Infection of a Joint caused by Staphylococcus Aureus
I got an infection in my hip replacement, which required me to get a new hip replacement and go on IV antibiotics for six weeks. This caused severe diarrhea, which turned into C-diff after two weeks. I had to take oral vancomycin four times a day for 10 months. I also experienced extreme muscle decay during this time.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about cefoxitin

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is cefoxitin a penicillin?

"Cefoxitin is a derivative of cephamycin, and is a second-generation cephalosporin. Like other cephalosporins, it inhibits cell wall synthesis by linking with penicillin-binding proteins to create an unstable bacterial cell wall. Resistance develops by alterations in penicillin-binding proteins."

Answered by AI

What type of antibiotic is cefoxitin?

"Cefoxitin belongs to a class of antibiotics called cephamycins, which work by killing bacteria."

Answered by AI

What is IV cefoxitin used for?

"Cefoxitin injection is a medication used to treat bacterial infections in many different parts of the body. This medicine is also given before certain types of surgery to prevent infection. Cefoxitin injection is a type of cephalosporin antibiotic."

Answered by AI

What is another name for cefoxitin?

"MEFOXIN is a semi-synthetic cepha antibiotic that is sealed under nitrogen for intravenous administration. It is derived from cephamycin C, which is produced by Streptomyces lactamdurans."

Answered by AI

Clinical Trials for Cefoxitin

Have you considered Cefoxitin clinical trials? We made a collection of clinical trials featuring Cefoxitin, we think they might fit your search criteria.
Have you considered Cefoxitin clinical trials? We made a collection of clinical trials featuring Cefoxitin, we think they might fit your search criteria.
Have you considered Cefoxitin clinical trials? We made a collection of clinical trials featuring Cefoxitin, we think they might fit your search criteria.