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What is Caverject Impulse
AlprostadilThe Generic name of this drug
Treatment SummaryAlprostadil is a medication used to treat a number of conditions. In infants, it is used to keep the ductus arteriosus (DA) open, which helps with blood flow. In adults, it is used to treat erectile dysfunction caused by physical, psychological, or mixed issues. Alprostadil relaxes and widens blood vessels, increasing blood flow in the body.
Prostin Vr Pediatricis the brand name
Caverject Impulse Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Prostin Vr Pediatric
Alprostadil
1981
28
Effectiveness
How Caverject Impulse Affects PatientsAlprostadil (prostaglandin E1) is a naturally occurring substance that causes blood vessels to widen (vasodilation) and improves blood flow. In adult males, this widening of the blood vessels in the penis causes increased blood flow, leading to an erection. In infants, alprostadil helps to increase the amount of blood flowing to the lungs or other parts of the body.
How Caverject Impulse works in the bodyAlprostadil helps to increase blood flow in the body. It does this by preventing or reversing the natural closure of the ductus arteriosus shortly after birth, and by relaxing the trabecular smooth muscle of the corpora cavernosa in the penis. When used in infants with cyanotic congenital heart disease, alprostadil helps to increase the oxygen supply to the tissues. When used in infants with aortic arch anomalies, it helps to increase systemic blood flow to the lower body, improving tissue oxygen supply and renal perfusion. In adults, it works by causing swelling, elongation, and rigidity of
When to interrupt dosage
The endorsed dosage of Caverject Impulse is contingent upon the diagnosed condition, such as Impotence, Raynaud's Phenomenon and Aquaporin 2. The amount of dosage fluctuates as per the delivery procedure featured in the below table.Condition
Dosage
Administration
Raynaud's Phenomenon
, 0.125 mg, 0.25 mg, 0.5 mg, 1.0 mg, 0.01 mg/mL, 0.02 mg/mL, 0.04 mg/mL, 0.0232 mg, 0.0119 mg, 0.0105 mg/mL, 0.0054 mg/mL, 0.5 mg/mL, 0.0205 mg/mL, 0.1 mg/mL, 0.0411 mg/mL, 0.2 mg/mL, 0.02 mg, 0.0033 mg/mg, 0.0022 mg/mg
, Urethral, Suppository, Suppository - Urethral, Intracavernous, Injection, powder, lyophilized, for solution - Intracavernous, Injection, powder, lyophilized, for solution, Kit; Liquid; Powder, for solution - Intracavernous, Kit; Liquid; Powder, for solution, Intra-arterial; Intravenous, Solution - Intra-arterial; Intravenous, Solution, Liquid, Liquid - Intra-arterial; Intravenous, Powder, for solution - Intracavernous, Powder, for solution, Topical, Cream - Topical, Cream, Intravascular, Injection, solution, concentrate, Injection, solution, concentrate - Intravascular, Intravascular; Intravenous, Injection, solution, Injection, solution - Intravascular; Intravenous, Solution - Intravascular, Injection, Injection - Intravascular; Intravenous
Impotence
, 0.125 mg, 0.25 mg, 0.5 mg, 1.0 mg, 0.01 mg/mL, 0.02 mg/mL, 0.04 mg/mL, 0.0232 mg, 0.0119 mg, 0.0105 mg/mL, 0.0054 mg/mL, 0.5 mg/mL, 0.0205 mg/mL, 0.1 mg/mL, 0.0411 mg/mL, 0.2 mg/mL, 0.02 mg, 0.0033 mg/mg, 0.0022 mg/mg
, Urethral, Suppository, Suppository - Urethral, Intracavernous, Injection, powder, lyophilized, for solution - Intracavernous, Injection, powder, lyophilized, for solution, Kit; Liquid; Powder, for solution - Intracavernous, Kit; Liquid; Powder, for solution, Intra-arterial; Intravenous, Solution - Intra-arterial; Intravenous, Solution, Liquid, Liquid - Intra-arterial; Intravenous, Powder, for solution - Intracavernous, Powder, for solution, Topical, Cream - Topical, Cream, Intravascular, Injection, solution, concentrate, Injection, solution, concentrate - Intravascular, Intravascular; Intravenous, Injection, solution, Injection, solution - Intravascular; Intravenous, Solution - Intravascular, Injection, Injection - Intravascular; Intravenous
Aquaporin 2
, 0.125 mg, 0.25 mg, 0.5 mg, 1.0 mg, 0.01 mg/mL, 0.02 mg/mL, 0.04 mg/mL, 0.0232 mg, 0.0119 mg, 0.0105 mg/mL, 0.0054 mg/mL, 0.5 mg/mL, 0.0205 mg/mL, 0.1 mg/mL, 0.0411 mg/mL, 0.2 mg/mL, 0.02 mg, 0.0033 mg/mg, 0.0022 mg/mg
, Urethral, Suppository, Suppository - Urethral, Intracavernous, Injection, powder, lyophilized, for solution - Intracavernous, Injection, powder, lyophilized, for solution, Kit; Liquid; Powder, for solution - Intracavernous, Kit; Liquid; Powder, for solution, Intra-arterial; Intravenous, Solution - Intra-arterial; Intravenous, Solution, Liquid, Liquid - Intra-arterial; Intravenous, Powder, for solution - Intracavernous, Powder, for solution, Topical, Cream - Topical, Cream, Intravascular, Injection, solution, concentrate, Injection, solution, concentrate - Intravascular, Intravascular; Intravenous, Injection, solution, Injection, solution - Intravascular; Intravenous, Solution - Intravascular, Injection, Injection - Intravascular; Intravenous
Warnings
Caverject Impulse has 14 incompatible contraindications, and should not be utilized if any of the circumstances in the following table is present.Caverject Impulse ContraindicationsCondition
Risk Level
Notes
predisposition to multiple myeloma
Do Not Combine
penis
Do Not Combine
Polycythemia
Do Not Combine
Thrombocythemia
Do Not Combine
predisposition to priapism
Do Not Combine
Disease
Do Not Combine
use for sexual intercourse
Do Not Combine
penile implants
Do Not Combine
leukemia
Do Not Combine
predisposition to sickle cell anemia
Do Not Combine
Pulse Frequency
Do Not Combine
men for whom sexual activity is inadvisable
Do Not Combine
Hyperviscosity syndrome
Do Not Combine
Pulse Frequency
Do Not Combine
Common Caverject Impulse Drug Interactions
Drug Name
Risk Level
Description
Captopril
Minor
The excretion of Captopril can be decreased when combined with Alprostadil.
Cefdinir
Minor
The excretion of Cefdinir can be decreased when combined with Alprostadil.
Citrulline
Minor
The excretion of Citrulline can be decreased when combined with Alprostadil.
Cyclic adenosine monophosphate
Minor
The excretion of Cyclic adenosine monophosphate can be decreased when combined with Alprostadil.
Didanosine
Minor
The excretion of Didanosine can be decreased when combined with Alprostadil.
Caverject Impulse Toxicity & Overdose RiskA toxic dose of the drug for a mouse is 186mg/kg and for a rat is 228mg/kg. Signs of an overdose may include difficulty breathing, a slow heartbeat, fever, low blood pressure, and flushed skin.
Caverject Impulse Novel Uses: Which Conditions Have a Clinical Trial Featuring Caverject Impulse?
27 active trials are assessing the potential of Caverject Impulse to ameliorate Aquaporin 2, Impotence, and Raynaud's Phenomenon.Condition
Clinical Trials
Trial Phases
Aquaporin 2
2 Actively Recruiting
Not Applicable, Phase 3
Impotence
26 Actively Recruiting
Not Applicable, Phase 4, Phase 1, Early Phase 1, Phase 3, Phase 2
Raynaud's Phenomenon
1 Actively Recruiting
Phase 4
Caverject Impulse Reviews: What are patients saying about Caverject Impulse?
5Patient Review
11/27/2011 Caverject was really easy to use, and I was surprised at how little pain there was. The 10mg dosage gave me an erection in just 10 minutes, which lasted for about 90 minutes. It was great not having to worry about losing my erection during sex.
5Patient Review
11/7/2010 I've been using this treatment for six years, and it's really helped me. I would recommend finding the perfect dose for you, as too high of a dose can lead to painful erections that last up to two hours.
5Patient Review
4/1/2013 This was a great treatment for me and I would recommend it to others.
4.7Patient Review
7/28/2009 I wasn't able to keep erections as well when I was around 63, which obviously led to a lot of problems. However, this drug has completely changed that for the better. It's affordable too, which is great.
4.7Patient Review
11/19/2011 This drug worked great for me. I was able to maintain my erection for about an hour and a half, which is perfect. There were no side effects that I experienced, which is also awesome.
4.3Patient Review
4/1/2010 I've been using this treatment since 1993, when I fractured my hip in an accident. The kind that has to be kept in the fridge is the only type that works for me; the other doesn't work at all. Celias and similar treatments don't work for me either.
4.3Patient Review
11/3/2010 This drug is really effective, working for more than an hour at a time. The only downside is that there's a bit of blood seepage from the injection site, but it's worth it for the results.
4.3Patient Review
11/27/2010 This treatment is easy to use and fast-acting; you can usually expect to be erect within 10-15 minutes. It's also effective every time, which is great. The downside is that it does require an injection, which some people may not be comfortable with. Additionally, the erection typically only lasts for a couple of hours. Despite these drawbacks, I would still say it's worth considering because it's relatively affordable compared to other options out there.
4.3Patient Review
7/12/2017 I was left feeling very weak after two rounds of cancer and associated treatments. This medication requires that you get over any discomfort with needles, but I promise that the needle included in the kit is tiny and you barely feel it at all. Just a small dot of blood at the injection site, and 5-10 minutes later I'm feeling like myself again. This effect lasts for about an hour and a half.
4.3Patient Review
10/13/2015 This is a great product, and I'm curious about how long the mixed solution will stay effective. Does anyone know?
4.3Patient Review
8/15/2009 I'm 67 and have been using this treatment for almost 8 years. I feel like it's given me a new lease on life. The injection hurts a little, but the rewards are beyond description.. Viagra didn't work well for me, so I prefer Caverjet because the effect is local not over the whole body!!
4.3Patient Review
10/3/2009 I really don't know where I would be today if I hadn't given this treatment a try. It's definitely not perfect, but it has helped me immensely. The injection was tough to get used to at first, but the benefits of the medication far outweighed that inconvenience.
4Patient Review
9/11/2009 This treatment is effective and works quickly, usually within 5-7 minutes.
4Patient Review
10/24/2009 This is an excellent treatment.
2.3Patient Review
3/11/2010 I had mixed results with this treatment; it worked two out of five times, but the three times it didn't work caused severe bruising.
1.7Patient Review
11/2/2010 The pain I felt after just one injection was unbearable and lasted for several hours. I wouldn't wish that experience on anyone.
1Patient Review
7/28/2009 I'm really scared to do this procedure. I've been told it goes under the skin or right into the shaft of the penis. Can anyone give me more information? I used to have a great sex life, but now I'm struggling. This is impacting my self-esteem and relationship satisfaction.
Patient Q&A Section about caverject impulse
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What is CAVERJECT IMPULSE used for?
"Caverject Impulse is a drug that helps with erectile dysfunction by increasing blood flow to the penis. It can also be used to help diagnose certain causes of erectile dysfunction."
Answered by AI
How long does the effect of Caverject last?
"This medication is designed to produce an erection that lasts for around an hour, and typically starts working within 5-20 minutes. However, it shouldn't be used more than three times a week, with at least one day in between each dose."
Answered by AI
How is CAVERJECT IMPULSE administered?
"You should injection the CAVERJECT IMPUSE on different sides of the penis each time and compress the injection site for 5 minutes with an alcohol swab or sterile gauze. CAVERJECT IMPUSE is only meant to be used once and should be thrown away after use."
Answered by AI
What's the difference between Caverject and CAVERJECT IMPULSE?
"CAVERJECT is injected into a specific area of the penis to produce an erection. CAVERJECT IMPULSE is for single use only and should be thrown away after use."
Answered by AI