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What is Anzemet
DolasetronThe Generic name of this drug
Treatment SummaryDolasetron is a medication used to prevent nausea and vomiting caused by cancer chemotherapy and surgery. It works by blocking serotonin, a chemical in the body that can cause nausea and vomiting. Dolasetron does not affect other types of serotonin receptors or dopamine receptors.
Anzemetis the brand name
Anzemet Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Anzemet
Dolasetron
1997
10
Effectiveness
How Anzemet Affects PatientsDolasetron is a medication that prevents nausea and vomiting caused by chemotherapy. It works by blocking a certain type of serotonin receptor (5-HT3) in the body, which is responsible for the reflex that causes these symptoms. This drug is specifically designed to affect this receptor and not interact with other serotonin receptors or dopamine receptors. It is related to other drugs that work in similar ways.
How Anzemet works in the bodyDolasetron is a drug that works to prevent vomiting. It works by blocking the effects of serotonin in the brain and digestive system. By blocking the serotonin, it prevents the body from being stimulated to vomit, thus reducing nausea and vomiting.
When to interrupt dosage
The measure of Anzemet is dependent upon the diagnosed condition, including Pharmacotherapy, Pharmacotherapy and Nausea. The dose likewise fluctuates per the method of delivery featured in the table beneath.Condition
Dosage
Administration
Nausea
, 50.0 mg, 100.0 mg, 100.0 mg/mL, 125.0 mg/mL, 50.0 mg/mL, 20.0 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Intravenous, Injection, Injection - Intravenous, Tablet, Tablet - Oral, Solution, Solution - Intravenous
Nausea
, 50.0 mg, 100.0 mg, 100.0 mg/mL, 125.0 mg/mL, 50.0 mg/mL, 20.0 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Intravenous, Injection, Injection - Intravenous, Tablet, Tablet - Oral, Solution, Solution - Intravenous
Pharmacotherapy
, 50.0 mg, 100.0 mg, 100.0 mg/mL, 125.0 mg/mL, 50.0 mg/mL, 20.0 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Intravenous, Injection, Injection - Intravenous, Tablet, Tablet - Oral, Solution, Solution - Intravenous
Pharmacotherapy
, 50.0 mg, 100.0 mg, 100.0 mg/mL, 125.0 mg/mL, 50.0 mg/mL, 20.0 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Intravenous, Injection, Injection - Intravenous, Tablet, Tablet - Oral, Solution, Solution - Intravenous
Warnings
Anzemet has two contraindications and should not be consumed when facing any of the conditions specified in the following table.Anzemet ContraindicationsCondition
Risk Level
Notes
emetogenic cancer chemotherapy, QT prolongation
Do Not Combine
emetogenic cancer chemotherapy, QT prolongation
Do Not Combine
Common Anzemet Drug Interactions
Drug Name
Risk Level
Description
Amitriptyline
Major
The metabolism of Amitriptyline can be decreased when combined with Dolasetron.
Amoxapine
Major
The metabolism of Amoxapine can be decreased when combined with Dolasetron.
Anagrelide
Major
The risk or severity of QTc prolongation can be increased when Dolasetron is combined with Anagrelide.
Apomorphine
Major
The risk or severity of hypotension can be increased when Dolasetron is combined with Apomorphine.
Arsenic trioxide
Major
The risk or severity of QTc prolongation can be increased when Dolasetron is combined with Arsenic trioxide.
Anzemet Novel Uses: Which Conditions Have a Clinical Trial Featuring Anzemet?
Two active investigations are assessing the potential of Anzemet to provide Pharmacotherapeutic relief and mitigate Nausea symptoms.Condition
Clinical Trials
Trial Phases
Pharmacotherapy
1 Actively Recruiting
Phase 4
Pharmacotherapy
0 Actively Recruiting
Nausea
0 Actively Recruiting
Nausea
3 Actively Recruiting
Not Applicable, Phase 2, Phase 3, Phase 4
Anzemet Reviews: What are patients saying about Anzemet?
5Patient Review
10/23/2015 This medication was incredibly helpful to me during chemotherapy. It alleviated the nausea I felt when taking Carboplatin and Temazolamide.
5Patient Review
11/29/2011 The medication was quite expensive, but it worked well. My insurance covered most of the cost, which was appreciated.
5Patient Review
8/8/2008Patient Q&A Section about anzemet
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What class of medication is anzemet?
"This drug is used to prevent nausea and vomiting caused by chemotherapy. It works by blocking the actions of a chemical substance called serotonin.
Anzemet tablets are a type of drug known as an antiemetic, which is a 5-HT3 antagonist. This drug is used to prevent nausea and vomiting caused by chemotherapy. It works by blocking the actions of a chemical substance called serotonin."
Answered by AI
Why was anzemet discontinued?
"The drug Anzemet should no longer be used to prevent nausea and vomiting associated with initial and repeat courses of emetogenic cancer chemotherapy because it can cause QT prolongation."
Answered by AI
How is anzemet administered?
"It is recommended that ANZEMET Injection (dolasetron mesylate injection) be given at a dosage of 12.5 mg intravenously, either 15 minutes before anesthesia ends (to prevent nausea and vomiting) or as soon as nausea or vomiting appears (to treat it)."
Answered by AI
What is the generic name for anzemet?
"Dolasetron is used to prevent nausea and vomiting caused by cancer chemotherapy.
The generic name for dolasetron is Dolasetron - Oral. It is used to prevent nausea and vomiting caused by cancer chemotherapy."
Answered by AI