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74 Epilepsy Trials Near You
Power is an online platform that helps thousands of Epilepsy patients discover FDA-reviewed trials every day. Every trial we feature meets safety and ethical standards, giving patients an easy way to discover promising new treatments in the research stage.
Learn More About PowerBHV-7000 for Epilepsy
Trial Details
Key Eligibility Criteria
390 Participants Needed
Cenobamate for Seizures
Trial Details
Key Eligibility Criteria
169 Participants Needed
BHV-7000 for Epilepsy
Trial Details
Key Eligibility Criteria
660 Participants Needed
Focused Ultrasound for Epilepsy
Trial Details
Key Eligibility Criteria
10 Participants Needed
DBS Therapy for Epilepsy
Trial Details
Key Eligibility Criteria
140 Participants Needed
Gene Therapy for Epilepsy
Trial Details
Key Eligibility Criteria
12 Participants Needed
Focused Ultrasound Thalamotomy for Epilepsy and Anxiety
Trial Details
Key Eligibility Criteria
10 Participants Needed
LP352 for Dravet Syndrome
Trial Details
Key Eligibility Criteria
160 Participants Needed
Cenobamate for Focal Seizures
Trial Details
Key Eligibility Criteria
90 Participants Needed
Zorevunersen for Dravet Syndrome
Trial Details
Key Eligibility Criteria
150 Participants Needed
EPX-100 for Dravet Syndrome
Trial Details
Key Eligibility Criteria
100 Participants Needed
LP352 for Epilepsy
Trial Details
Key Eligibility Criteria
324 Participants Needed
LP352 for Epilepsy
Trial Details
Key Eligibility Criteria
320 Participants Needed
XEN1101 for Partial Seizures
Trial Details
Key Eligibility Criteria
360 Participants Needed
XEN1101 for Seizures
Trial Details
Key Eligibility Criteria
160 Participants Needed
XEN1101 for Epilepsy
Trial Details
Key Eligibility Criteria
325 Participants Needed
Cannabidiol for Chronic Liver Injury Prevention
Trial Details
Key Eligibility Criteria
154 Participants Needed
Cenobamate for Epilepsy
Trial Details
Key Eligibility Criteria
140 Participants Needed
Fenfluramine for CDKL5 Deficiency Disorder
Trial Details
Key Eligibility Criteria
87 Participants Needed
Cenobamate (Xcopri) for Seizures
Trial Details
Key Eligibility Criteria
24 Participants Needed
Why Other Patients Applied
"As a healthy volunteer, I like to participate in as many trials as I'm able to. It's a good way to help research and earn money."
"I changed my diet in 2020 and I’ve lost 95 pounds from my highest weight (283). I am 5’3”, female, and now 188. I still have a 33 BMI. I've been doing research on alternative approaches to continue my progress, which brought me here to consider clinical trials."
"I've been struggling with ADHD and anxiety since I was 9 years old. I'm currently 30. I really don't like how numb the medications make me feel. And especially now, that I've lost my grandma and my aunt 8 days apart, my anxiety has been even worse. So I'm trying to find something new."
"I've tried several different SSRIs over the past 23 years with no luck. Some of these new treatments seem interesting... haven't tried anything like them before. I really hope that one could work."
"I was diagnosed with stage 4 pancreatic cancer three months ago, metastatic to my liver, and I have been receiving and responding well to chemotherapy. My blood work revealed that my tumor markers have gone from 2600 in the beginning to 173 as of now, even with the delay in treatment, they are not going up. CT Scans reveal they have been shrinking as well. However, chemo is seriously deteriorating my body. I have 4 more treatments to go in this 12 treatment cycle. I am just interested in learning about my other options, if any are available to me."
Cannabidiol for Seizures
Trial Details
Key Eligibility Criteria
27 Participants Needed
Web-Based Program for Teens with Epilepsy
Trial Details
Key Eligibility Criteria
310 Participants Needed
Sirolimus for Tuberous Sclerosis
Trial Details
Key Eligibility Criteria
64 Participants Needed
Ganaxolone for TSC-Related Epilepsy
Trial Details
Key Eligibility Criteria
132 Participants Needed
Medical Cannabis for Chronic Pain
Trial Details
Key Eligibility Criteria
200000 Participants Needed
XEN1101 for Epilepsy
Trial Details
Key Eligibility Criteria
880 Participants Needed
XEN1101 for Seizures
Trial Details
Key Eligibility Criteria
360 Participants Needed
Vatiquinone Safety for Mitochondrial Disease
Trial Details
Key Eligibility Criteria
102 Participants Needed
Soticlestat for Dravet Syndrome
Trial Details
Key Eligibility Criteria
400 Participants Needed
Satralizumab for Autoimmune Encephalitis
Trial Details
Key Eligibility Criteria
152 Participants Needed
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We started Power when my dad was diagnosed with multiple myeloma, and I struggled to help him access the latest immunotherapy. Hopefully Power makes it simpler for you to explore promising new treatments, during what is probably a difficult time.
Frequently Asked Questions
How much do Epilepsy clinical trials pay?
Each trial will compensate patients a different amount, but $50-100 for each visit is a fairly common range for Phase 2–4 trials (Phase 1 trials often pay substantially more). Further, most trials will cover the costs of a travel to-and-from the clinic.
How do Epilepsy clinical trials work?
After a researcher reviews your profile, they may choose to invite you in to a screening appointment, where they'll determine if you meet 100% of the eligibility requirements. If you do, you'll be sorted into one of the treatment groups, and receive your study drug. For some trials, there is a chance you'll receive a placebo. Across Epilepsy trials 30% of clinical trials have a placebo. Typically, you'll be required to check-in with the clinic every month or so. The average trial length for Epilepsy is 12 months.
How do I participate in a study as a "healthy volunteer"?
Not all studies recruit healthy volunteers: usually, Phase 1 studies do. Participating as a healthy volunteer means you will go to a research facility several times over a few days or weeks to receive a dose of either the test treatment or a "placebo," which is a harmless substance that helps researchers compare results. You will have routine tests during these visits, and you'll be compensated for your time and travel, with the number of appointments and details varying by study.
What does the "phase" of a clinical trial mean?
The phase of a trial reveals what stage the drug is in to get approval for a specific condition. Phase 1 trials are the trials to collect safety data in humans. Phase 2 trials are those where the drug has some data showing safety in humans, but where further human data is needed on drug effectiveness. Phase 3 trials are in the final step before approval. The drug already has data showing both safety and effectiveness. As a general rule, Phase 3 trials are more promising than Phase 2, and Phase 2 trials are more promising than phase 1.
Do I need to be insured to participate in a Epilepsy medical study?
Clinical trials are almost always free to participants, and so do not require insurance. The only exception here are trials focused on cancer, because only a small part of the typical treatment plan is actually experimental. For these cancer trials, participants typically need insurance to cover all the non-experimental components.
What are the newest Epilepsy clinical trials?
Most recently, we added Subcortical Arousal Study for Epilepsy, Zonisamide for Partial Seizures and Zorevunersen for Dravet Syndrome to the Power online platform.
What are the current treatments for epilepsy?
Treatment usually starts with daily anti-seizure medicines—over 20 are available—and about two-thirds of people become seizure-free after trying one or two of them. If seizures continue, specialists can offer individualized next steps such as surgery to remove the seizure focus, implantable stimulators that “pace” the nerves or brain (VNS, RNS, deep-brain stimulation), dietary therapy like the ketogenic or modified Atkins diet, or newer drugs including purified cannabidiol. The best plan depends on seizure type, age, other health issues and personal preferences, so care is built in partnership with an epilepsy team.
Are you born with epilepsy or does it develop?
Epilepsy can start two ways: you might be born with an underlying change in the brain — for example a genetic mutation or a problem that occurred during pregnancy or birth — or you can develop it later after things like a head injury, stroke, tumour or serious brain infection. Roughly one-third of cases are clearly “present from birth,” another third are due to later brain injuries or illnesses, and the rest have no obvious cause yet. In short, some people are born with the tendency, but anyone can develop epilepsy at any age if new damage or disease affects the brain’s electrical circuits.
What is the rule of 3 for seizures?
The ILAE’s “Rule of 3” says you can call someone seizure-free when they have gone at least three times as long as their single longest gap between seizures before the new treatment—and in any case at least 12 months—without another event. For example, if the longest break before treatment was 2 months, you need 6 months but because the rule also sets a 12-month minimum you would actually wait a full year; if the longest break was 8 months, you would need 24 months seizure-free. This personalised yard-stick helps doctors judge whether an intervention is truly working and avoids declaring success either too early (for people who naturally had long intervals) or too late (for those who seized frequently).
What is the most serious epilepsy?
The most immediately life-threatening situation is status epilepticus—any seizure that lasts five minutes or more or comes back before the person regains awareness; if this happens, give any prescribed rescue medicine and call emergency services because every extra minute increases the risk of brain injury or death. Over the long term, rare drug-resistant childhood syndromes such as Dravet or Lennox-Gastaut are often labeled the “most serious” because they cause daily seizures, developmental problems, and a higher risk of sudden death, so they require care at a specialized epilepsy center and a written emergency plan.
How likely is epilepsy to go away?
About two-thirds of children and roughly 60 % of adults who are just starting treatment become seizure-free long-term with medication alone. If seizures continue after trying two suitable drugs, the chance they stop on their own is small (under 5 % per year), but surgery or other specialised treatments can lift the seizure-free rate to about 50-70 % in people who are good candidates. Your exact odds depend on the epilepsy type, brain scans and early response to medicine, so work with your neurologist before deciding whether to stay on, stop, or escalate treatment.
What foods prevent seizures?
No single food can guarantee seizure prevention. What has solid evidence is a medically supervised, high-fat/very-low-carb diet (classic ketogenic or its easier cousins, the modified Atkins and low-glycaemic-index plans), which can reduce seizure frequency in about half of patients and make some seizure-free. If you’re not on one of these programs, aim for steady blood-sugar meals—plenty of non-starchy vegetables, healthy fats (olive oil, avocado, nuts, fatty fish), regular protein, and minimal added sugar—and talk with your neurologist or a dietitian before making major changes.
What do people with epilepsy struggle with?
People with epilepsy usually face two overlapping hurdles: the seizures themselves—figuring out triggers, preventing injuries, and coping with restrictions on driving, work, or sports—and the wider “after-shocks,” such as memory lapses, mood problems, medication side-effects, stigma, and added financial or school stress. Pinpointing which of these areas is causing the most strain and partnering with a neurologist on medication adherence, mental-health care, safety planning, and community support can greatly reduce risk and help regain independence.
What is the difference between a seizure and an epilepsy?
Think of a seizure as a one-time electrical “short-circuit” in the brain that can be set off by things like fever, low blood sugar, or head injury; once the trigger is gone, the risk may disappear. Epilepsy is the medical disorder in which the brain itself has an ongoing tendency to seize—diagnosed when someone has at least two unprovoked seizures (or one unprovoked seizure with a high chance of another), so the focus shifts from treating a single event to managing a long-term condition.
What is the best epilepsy hospital in the world?
There is no single “best” epilepsy hospital; what matters is choosing a center that holds the top accreditation for complex epilepsy care (e.g., NAEC Level 4 in the U.S. or an equivalent comprehensive program elsewhere), performs a high number of epilepsy surgeries with good outcomes, and has a multidisciplinary team and active research program. Examples that fit these benchmarks include Mayo Clinic and Cleveland Clinic (USA), King’s College Hospital/UCL in London (UK), University of Bonn (Germany), Pitié-Salpêtrière (France), Toronto Western Hospital (Canada), and Tokyo University Hospital (Japan). Ask your neurologist or local epilepsy foundation which accredited comprehensive center is closest and best suited to your insurance, travel limits, and whether you need adult or pediatric care.
What is the best exercise for a seizure patient?
There’s no single “best” exercise for epilepsy—the goal is to choose any activity you enjoy (brisk walking, cycling, swimming with a buddy, light weights, yoga) and do it regularly enough to meet general health targets of ~150 minutes of moderate movement plus two strength sessions weekly. Apply a safety layer: take medications on schedule, avoid personal triggers, wear a medical ID, and have supervision for water or height-related sports; studies and international guidelines show this approach improves fitness, mood, and often reduces seizures without added risk. Always confirm details with your neurologist so the plan fits your seizure pattern and other health factors.