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Allegheny General Hospital

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Pittsburgh, Pennsylvania 15212

Global Leader in Breast Cancer

Global Leader in Lung Cancer

Conducts research for Pulmonary Arterial Hypertension

Conducts research for Heart Failure

Conducts research for Cancer

473 reported clinical trials

61 medical researchers

Photo of Allegheny General Hospital in PittsburghPhoto of Allegheny General Hospital in Pittsburgh

Summary

Allegheny General Hospital is a medical facility located in Pittsburgh, Pennsylvania. This center is recognized for care of Breast Cancer, Lung Cancer, Pulmonary Arterial Hypertension, Heart Failure, Cancer and other specialties. Allegheny General Hospital is involved with conducting 473 clinical trials across 677 conditions. There are 61 research doctors associated with this hospital, such as Thomas Krivak, Gene G. Finley, Sarah Crafton, and Dulabh Monga, MD.

Area of expertise

1

Breast Cancer

Global Leader

Allegheny General Hospital has run 54 trials for Breast Cancer. Some of their research focus areas include:

HER2 negative
ER positive
Stage II
2

Lung Cancer

Global Leader

Allegheny General Hospital has run 49 trials for Lung Cancer. Some of their research focus areas include:

Stage IV
Stage III
Stage II

Top PIs

Clinical Trials running at Allegheny General Hospital

Skin Cancer

Breast Cancer

Bladder Cancer

Cancer

Pancreatic Cancer

Bladder Carcinoma

Lung Cancer

Liver Cancer

Kidney Cancer

Breast cancer

Image of trial facility.

Cemiplimab + Surgery

for Advanced Skin Cancer

This phase III trial compares the effect of adding cemiplimab to standard therapy (surgery with or without radiation) versus standard therapy alone in treating patients with stage III/IV squamous cell skin cancer that is able to be removed by surgery (resectable) and that may have come back after a period of improvement (recurrent). The usual treatment for patients with resectable squamous cell skin cancer is the removal of the cancerous tissue (surgery) with or without radiation, which uses high energy x-rays, particles, or radioactive seeds to kill cancer cells and shrink tumors. Immunotherapy with monoclonal antibodies, such as cemiplimab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Cemiplimab has been approved for the treatment of skin cancer that has spread or that cannot be removed by surgery, but it has not been approved for the treatment of skin cancer than can be removed by surgery. Adding cemiplimab to the usual treatment of surgery with or without radiation may be more effective in treating patients with stage III/IV resectable squamous cell skin cancer than the usual treatment alone.

Recruiting

2 awards

Phase 3

7 criteria

Image of trial facility.

Gabapentin

for Pain in Head and Neck Cancer

This phase III trial tests if gabapentin can prevent the need for opiate pain medication for mouth sores (oral mucositis) in patients undergoing treatment with chemotherapy and radiation for squamous cell carcinoma of the head and neck region. Oral mucositis is a common side effect of radiation treatment and can cause severe pain, dysphagia, and weight loss resulting in feeding tube placement, worse health-related quality of life, treatment interruptions, unplanned hospitalizations, and significant financial burden. Mucositis pain is often treated with opioid pain medications which do provide pain relief but have many known side effects not limited to mental clouding, constipation, fatigue, endocrinopathy, neurotoxicity, sleep-disordered breathing, and most distressingly persistent opioid use. Gabapentin may help relieve pain from oral mucositis caused by radiation while also reducing the need for opiate pain medications for patients receiving chemotherapy and radiation for squamous cell carcinoma of the head and neck region

Recruiting

1 award

Phase 3

14 criteria

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