Dr. Sarah Crafton
Claim this profileWest Penn Hospital
Studies Ovarian Cancer
Studies Parotid Gland Cancer
13 reported clinical trials
22 drugs studied
Area of expertise
1Ovarian Cancer
BRCA1 positive
Stage IV
Mismatch Repair Deficiency positive
2Parotid Gland Cancer
Stage IV
Stage III
HER2 positive
Affiliated Hospitals
Clinical Trials Sarah Crafton is currently running
Olvi-Vec + Chemotherapy
for Ovarian Cancer
The OnPrime study is a multi-center, randomized open-label phase 3 study evaluating the safety and efficacy of Olvi-Vec followed by platinum-doublet chemotherapy and bevacizumab compared to the Active Comparator Arm with Physician's Choice of chemotherapy and bevacizumab in women diagnosed with platinum-resistant/refractory ovarian cancer (includes fallopian tube cancer and primary peritoneal cancer). This Phase III trial builds on the efficacy and safety data reported in the previous Phase II VIRO-15 trial with promising objective response rate and progression-free survival observed in heavily pre-treated patients with platinum-resistant/refractory ovarian cancer. The phase II results also showed that the intra-peritoneal route of delivery was efficient in generating tumor cell killing and immune activation, and led to clinical reversal of platinum-resistance or refractoriness in this difficult-to-treat patient population.
Recruiting2 awards Phase 37 criteria
ACR-368
for Ovarian Cancer
This trial tests a new drug, ACR-368, alone or with a small dose of another drug, gemcitabine, in patients whose cancers don't respond to standard treatments. A special test helps decide which treatment might work best for each patient. Gemcitabine has been used with other drugs for various cancers, including pancreatic, lung, ovarian, and breast cancers.
Recruiting1 award Phase 210 criteria
More about Sarah Crafton
Clinical Trial Related5 years of experience running clinical trials · Led 13 trials as a Principal Investigator · 8 Active Clinical TrialsTreatments Sarah Crafton has experience with
- Paclitaxel
- Carboplatin
- Pembrolizumab
- Bevacizumab
- Mirvetuximab Soravtansine
- Gemcitabine
Breakdown of trials Sarah Crafton has run
Ovarian Cancer
Parotid Gland Cancer
Endometrial Cancer
Cervical Adenocarcinoma
Fallopian Tube Cancer
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