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University of Pittsburgh
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Pittsburgh, Pennsylvania 15213
Global Leader in Alzheimer's Disease
Global Leader in Depression
Conducts research for Stroke
Conducts research for Obesity
Conducts research for Motor Skills
1005 reported clinical trials
117 medical researchers
Summary
University of Pittsburgh is a medical facility located in Pittsburgh, Pennsylvania. This center is recognized for care of Alzheimer's Disease, Depression, Stroke, Obesity, Motor Skills and other specialties. University of Pittsburgh is involved with conducting 1,005 clinical trials across 1,313 conditions. There are 117 research doctors associated with this hospital, such as Jason Luke, MD, Diwakar Davar, MD, Adam Brufsky, MD, and Anwaar Saeed.
Area of expertise
Alzheimer's Disease
University of Pittsburgh has run 45 trials for Alzheimer's Disease. Some of their research focus areas include:
Depression
University of Pittsburgh has run 44 trials for Depression. Some of their research focus areas include:
Top PIs
Jason Luke, MD
University of Pittsburgh Medical Center
1 year of reported clinical research
Diwakar Davar, MD
UPMC Hillman Cancer Center
7 years of reported clinical research
Adam Brufsky, MD
University of Pittsburgh Cancer Institute (UPCI)
2 years of reported clinical research
Anwaar Saeed
University of Kansas Cancer Center
4 years of reported clinical research
Clinical Trials running at University of Pittsburgh
Depression
Breast Cancer
Spinal Cord Injury
Pancreatic Cancer
Chronic Persistent Surgical Pain
Attention Deficit Hyperactivity Disorder (ADHD)
Gestational Diabetes
Obesity
Traumatic Brain Injury
Alzheimer's Disease
Treatments
for Depression
This is a multi-site randomized control trial involving people age 55+ years who have current depression symptoms plus another suicide risk indicator (either current suicidal ideation or a past history of attempt). Our goal is evaluate which of two different approaches works best to improve things like trouble sleeping, bad moods, and any suicidality. Participants will complete diagnostic interviews, self-report scales, and wear an actigraphy device for the 8 weeks starting at the baseline visit.
Recruiting
1 award
N/A
3 criteria
Parent Coaching
for Parent-Child Relationship
The goal of this mechanistic clinical trial is to examine whether parent-coaching aimed at increasing child positive affect will increase child neural response to reward. The main questions it aims to answer are: Aim 1. Characterize child neural reward response and its relation to maternal socialization of positive emotions at baseline in healthy young children. Aim 2. Evaluate how coaching-related changes in maternal socialization of positive emotion expression contribute to increases in child neural reward response over time. Aim 3. Examine how maternal socialization of positive emotion expression contributes to increases in child neural reward response in the moment. Participating mother-child dyads will be randomized to either 3 sessions of parent coaching of child positive affect or 3 sessions of a general parenting support intervention and neural response to reward and affective behavior will be examined pre and post intervention.
Recruiting
1 award
N/A
1 criteria
Social Media Effects
for Teen Depression
There has been much interest in the potential role of social media (SM) use in driving a current mental health crisis among teens, with a dire need for evidence that goes beyond self-report. One important avenue is to understand the role of the brain in driving the effects of SM use on emotional health and vice versa. However, there is almost no research addressing these questions, largely due to a lack of tasks that can probe the neural correlates of modern SM use. The goal of this clinical trial is to develop and validate a new developmentally-appropriate and ecologically-valid functional magnetic resonance imaging (fMRI) and eyetracking task, the TeenBrainOnline (TBO) Task, that is more realistic and similar to modern SM platforms. Participants will be 50 teens (ages 13-17) with depressive symptoms who will complete the final version of TBO task during fMRI with eye-tracking, an older Chatroom Interact (CHAT-I) Task, daily surveys of SM use, and measures of depressive symptoms. Our goal is to show that the task works by: * Demonstrating that it activates expected regions of the brain and visual attention biases toward feedback cues. * Showing that brain and eyetracking (visual attention) activity on the task explain variability in depressive symptoms at baseline and three months later, and work better than similar indices from an older task. * Showing that brain and eyetracking (visual attention) activity on the task are associated with real-world measures of social media use collected during daily surveys. Specifically, The investigators expect that teens whose brain and eyetracking activity suggests they are more sensitive to feedback on SM will report a social evaluation orientation toward social media use in daily life, such as engaging a lot in social comparison, worrying about missing out, and caring about getting a lot of likes and comments. Participants will be asked to: * complete a 10-15 minute screening call to determine eligibility for the study * complete one 90 minute virtual study visit to complete questionnaires and prepare for the MRI visit (visit 1) * submit 24 photos to our study specific social media site * complete an (in person) MRI scan visit (\~4 hours), which consists of 2 tasks where they will interact with peers (visit 2) * complete \~5 minute smartphone surveys 3 times a day for 16 days, asking about their daily experiences online and emotional reactions. * complete 2 online questionnaires asynchronously 3 months after their scan date
Recruiting
1 award
N/A
2 criteria
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Frequently asked questions
What kind of research happens at University of Pittsburgh?
University of Pittsburgh is a medical facility located in Pittsburgh, Pennsylvania. This center is recognized for care of Alzheimer's Disease, Depression, Stroke, Obesity, Motor Skills and other specialties. University of Pittsburgh is involved with conducting 1,005 clinical trials across 1,313 conditions. There are 117 research doctors associated with this hospital, such as Jason Luke, MD, Diwakar Davar, MD, Adam Brufsky, MD, and Anwaar Saeed.
Where is University of Pittsburgh located?
**University of Pittsburgh Medical Center (UPMC) Presbyterian Hospital** - **Address:** 200 Lothrop Street, Pittsburgh, PA, 15213. Located in the Department of Neurological Surgery. - **Parking:** Valet parking and a parking garage are available nearby. **UPMC Shadyside** - **Directions:** From the Pennsylvania Turnpike, take Exit 57 (Pittsburgh/Monroeville) to I-376 West. Follow signs to S. Aiken Ave and turn right. - **Parking:** Pay parking available in the Aiken Avenue Parking Garage.
Who should I call to ask about financial aid or insurance network?
For general inquiries about student health coverage, contact the University's Benefits Department at 833-852-2210 or submit an inquiry online. For enrollment questions, contact UPMC Health Plan at 1-888-499-6885. For hospital bill inquiries, reach out to UPMC Patient Financial Services Center at 1-800-371-8359 or email PatientFinancialServicesCenter@upmc.edu. For UPMC Health Plan bill questions, contact Member Services at 1-888-876-2756 or TTY 711. During your hospital stay, direct questions to your case manager.
What insurance does University of Pittsburgh accept?
The University of Pittsburgh primarily accepts insurance through UPMC Health Plan, offering a variety of medical benefit plans for faculty, staff, and students, including HMO and PPO options. Student-specific plans provide comprehensive coverage with a modest deductible, and re-enrollment is required every fall to maintain active coverage. For international students, scholars, and family members, the university offers health insurance through the Office of International Services and other external options like Highmark Blue Cross/Blue Shield and the Children's Health Insurance Program (CHIP).
What awards or recognition has University of Pittsburgh received?
The University of Pittsburgh Medical Center (UPMC) in Pittsburgh, Pennsylvania, is renowned for its exceptional research and care, earning it numerous awards and recognitions. Notably, UPMC has been named a 2024 High Performing Center of Excellence by the U.S. Department of Health and Human Services and has received the American Heart Association/American Stroke Association Get With The Guidelines® - Stroke Gold Plus Award. It is also recognized as one of America's 100 Best Hospitals for Prostate Cancer and Gastrointestinal Surgery by Healthgrades, among other prestigious honors such as the HAP Donate Life Challenge CORE Hospital Designation – Titanium and the Healthcare Equality Index (HEI) Leader and Top Performer designations.
Unbiased Results
We believe in providing patients with all the options.
Your Data Stays Your Data
We only share your information with the clinical trials you're trying to access.
Verified Trials Only
All of our trials are run by licensed doctors, researchers, and healthcare companies.
Unbiased Results
We believe in providing patients with all the options.
Your Data Stays Your Data
We only share your information with the clinical trials you're trying to access.
Verified Trials Only
All of our trials are run by licensed doctors, researchers, and healthcare companies.