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University of Pittsburgh
Claim this profilePittsburgh, Pennsylvania 15213
Global Leader in Alzheimer's Disease
Global Leader in Depression
Conducts research for Obesity
Conducts research for Peroneal Nerve Injury
Conducts research for Breast Cancer
1005 reported clinical trials
117 medical researchers
Summary
University of Pittsburgh is a medical facility located in Pittsburgh, Pennsylvania. This center is recognized for care of Alzheimer's Disease, Depression, Obesity, Peroneal Nerve Injury, Breast Cancer and other specialties. University of Pittsburgh is involved with conducting 1,005 clinical trials across 1,274 conditions. There are 117 research doctors associated with this hospital, such as Jason Luke, MD, Diwakar Davar, MD, Adam Brufsky, MD, and Anwaar Saeed.Area of expertise
1Alzheimer's Disease
Global LeaderAPP positive
PSEN1 positive
PSEN2 positive
2Depression
Global LeaderTop PIs
Jason Luke, MDUniversity of Pittsburgh Medical Center1 year of reported clinical research
Expert in Cancer
Expert in Solid Tumors
39 reported clinical trials
67 drugs studied
Diwakar Davar, MDUPMC Hillman Cancer Center7 years of reported clinical research
Expert in Melanoma
Studies Cancer
34 reported clinical trials
48 drugs studied
Adam Brufsky, MDUniversity of Pittsburgh Cancer Institute (UPCI)1 year of reported clinical research
Expert in Breast Cancer
Expert in Breast cancer
31 reported clinical trials
70 drugs studied
Anwaar SaeedUniversity of Kansas Cancer Center3 years of reported clinical research
Studies Colorectal Cancer
Studies Cervical Adenocarcinoma
20 reported clinical trials
37 drugs studied
Clinical Trials running at University of Pittsburgh
Depression
Breast Cancer
Attention Deficit Hyperactivity Disorder (ADHD)
Urinary Incontinence
Gestational Diabetes
Cancer
Spinal Cord Injury
Spinal Muscular Atrophy
Lower Back Pain
Peroneal Nerve Injury
Treatments
for Depression
This is a multi-site randomized control trial involving people age 55+ years who have current depression symptoms plus another suicide risk indicator (either current suicidal ideation or a past history of attempt). Our goal is evaluate which of two different approaches works best to improve things like trouble sleeping, bad moods, and any suicidality. Participants will complete diagnostic interviews, self-report scales, and wear an actigraphy device for the 8 weeks starting at the baseline visit.
Recruiting1 award N/A3 criteria
Social Media Effects
for Teen Depression
There has been much interest in the potential role of social media (SM) use in driving a current mental health crisis among teens, with a dire need for evidence that goes beyond self-report. One important avenue is to understand the role of the brain in driving the effects of SM use on emotional health and vice versa. However, there is almost no research addressing these questions, largely due to a lack of tasks that can probe the neural correlates of modern SM use. The goal of this clinical trial is to develop and validate a new developmentally-appropriate and ecologically-valid functional magnetic resonance imaging (fMRI) and eyetracking task, the TeenBrainOnline (TBO) Task, that is more realistic and similar to modern SM platforms. Participants will be 50 teens (ages 13-17) with depressive symptoms who will complete the final version of TBO task during fMRI with eye-tracking, an older Chatroom Interact (CHAT-I) Task, daily surveys of SM use, and measures of depressive symptoms. Our goal is to show that the task works by: * Demonstrating that it activates expected regions of the brain and visual attention biases toward feedback cues. * Showing that brain and eyetracking (visual attention) activity on the task explain variability in depressive symptoms at baseline and three months later, and work better than similar indices from an older task. * Showing that brain and eyetracking (visual attention) activity on the task are associated with real-world measures of social media use collected during daily surveys. Specifically, The investigators expect that teens whose brain and eyetracking activity suggests they are more sensitive to feedback on SM will report a social evaluation orientation toward social media use in daily life, such as engaging a lot in social comparison, worrying about missing out, and caring about getting a lot of likes and comments. Participants will be asked to: * complete a 10-15 minute screening call to determine eligibility for the study * complete one 90 minute virtual study visit to complete questionnaires and prepare for the MRI visit (visit 1) * submit 24 photos to our study specific social media site * complete an (in person) MRI scan visit (\~4 hours), which consists of 2 tasks where they will interact with peers (visit 2) * complete \~5 minute smartphone surveys 3 times a day for 16 days, asking about their daily experiences online and emotional reactions. * complete 2 online questionnaires asynchronously 3 months after their scan date
Recruiting1 award N/A2 criteria
Sleep and Circadian Intervention
for Depression
The goal of this clinical trial is to adapt a sleep intervention for individuals representative of all demographic groups, including those who are at the highest risk for suicidal behavior. Sleep difficulties are a promising target for youth with suicidal thoughts and behavior to focus on as a prevention measure. We aim to increase intervention acceptability and impact by adapting it for the adolescent populations at highest risk for suicidal thoughts and behavior. The research project will compare Transdiagnostic Sleep and Circadian Intervention (TranS-C), an evidence based, modularized intervention that targets a range of sleep difficulties to a treatment as usual or control condition including providing weekly sleep feedback reports from data entered into a daily sleep diary and from wearing a sleep sensing, actigraphy watch. Participants in both conditions (TranS-C vs. Sleep Feedback) will wear an actigraphy sleep watch that monitors sleep, and complete daily sleep diaries via smartphone or email. Participants in the TranS-C condition will also wear bright light (BL) and blue blocking glasses each day as well as attend weekly or biweekly sessions with a Sleep Therapist. The sleep therapist will review sleep feedback during sessions.
Recruiting1 award N/A4 criteria
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Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.