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Amnion-Chorion Membrane for Wound Healing

N/A

Waitlist Available

Led By Muhammad Saleh, BDS, MSD

Research Sponsored by University of Michigan

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 6 months

Awards & highlights

Study Summary

This trial tests if a new type of plug helps bones heal better than standard plugs. #bonehealing

Who is the study for?

This trial is for individuals aged 20-80 needing tooth extraction due to decay, gum disease, fracture, or non-restorable conditions and interested in dental implants. They must have a healthy socket with minimal damage and no infection. Exclusions include liver/kidney issues, uncontrolled diabetes, pregnancy/breastfeeding, blood disorders, active infections or cancer treatments, poor oral hygiene, heavy smokers (10+ cigarettes/day), allergies to study meds like chlorhexidine.Check my eligibility

What is being tested?

The study tests if adding an amnion-chorion membrane on top of the standard collagen plug used in socket preservation leads to better bone formation after tooth extraction. This could improve outcomes for patients getting dental implants following extractions.See study design

What are the potential side effects?

While not explicitly stated here, potential side effects may include discomfort at the site of surgery, swelling or bruising around the area where the tooth was extracted and treated with membranes and plugs.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 6 months

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~6 months

This trial's timeline: 3 weeks for screening, Varies for treatment, and 6 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Alveolar ridge

Secondary outcome measures

Esthetic restorative outcomes.

Osteopenia

Implant survival-Clinical

+2 more

Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: TestExperimental Treatment1 Intervention

Amnion-chorion membrane with collagen plug

Group II: ControlActive Control1 Intervention

Collagen plug

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Socket preservation

2019

Completed Phase 4

~50

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

University of MichiganLead Sponsor

1,796 Previous Clinical Trials

6,377,923 Total Patients Enrolled

4 Trials studying Wound Healing

279 Patients Enrolled for Wound Healing

Muhammad Saleh, BDS, MSDPrincipal InvestigatorUniversity of Michigan

3 Previous Clinical Trials

82 Total Patients Enrolled

Media Library

Socket Preservation (Other) Clinical Trial Eligibility Overview. Trial Name: NCT05592158 — N/A

Wound Healing Research Study Groups: Control, Test

Wound Healing Clinical Trial 2023: Socket Preservation Highlights & Side Effects. Trial Name: NCT05592158 — N/A

Socket Preservation (Other) 2023 Treatment Timeline for Medical Study. Trial Name: NCT05592158 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is there an age limit to those who may participate in this experiment?

"In accordance with the guidelines of this medical trial, those hoping to be enrolled must meet a minimum age requirement of 20 and cannot exceed 80 years old."

Answered by AI

How does this experiment seek to advance medical knowledge?

"The primary end-points of this clinical trial, assessed over a 4 month period, is changes to the digital alveolar ridge dimension. Secondary outcomes being tracked are esthetic restorative outcomes (evaluated using the PES score), histomorphometry related to bone density and implant survival as clinically evaluated through torque testing in newtons per centimetre."

Answered by AI

Do I qualify for enrollment into this experiment?

"To become a part of this trial, interested parties should have wound healing and be aged between 20 to 80 years old. Currently, approximately 30 participants are required for the undertaking."

Answered by AI

Are there currently open spots for those interested in participating in this trial?

"The clinicaltrials.gov website reports that this medical research is no longer seeking new participants, though the original posting was on November 1st 2022 and it received an update as recently as October 21st 2022. However, there are currently 45 other related trials actively recruiting patients."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Evaluation of the Effectiveness of an Amnion-chorion Membrane for Alveolar Ridge Preservation

Muhammad Saleh 2022. "Evaluation of the Effectiveness of an Amnion-chorion Membrane for Alveolar Ridge Preservation". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05592158.