Orientation and Mobility Training with VR-IOMSs for Vision, Low

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Vision, Low+1 More
Orientation and Mobility Training with VR-IOMSs - Behavioral
Eligibility
Any Age
All Sexes
What conditions do you have?
Select

Study Summary

This trial tests the effectiveness of three Virtual Reality-based Intelligent Orientation and Mobility Specialists (VR-IOMSs) in teaching orientation and mobility (O&M) task skills to low vision patients. It will be conducted on two sites, University of Alabama at Birmingham (UAB) and Alabama Institute for Deaf and Blind (AIDB). The same protocol will be used on both sites. UAB will be the sIRB for the trial.

Eligible Conditions
  • Vision, Low
  • Eye

Treatment Effectiveness

Study Objectives

1 Primary · 3 Secondary · Reporting Duration: Within 30 minutes after completion of VR-IOMS training

Month 3
Training effect retainment
From the commencement of orientation & mobility training to its completion (may spread in multiple days) / within one week
Training duration
Day 3
Training effectiveness
Within 30 minutes after completion of VR-IOMS training
Subjective learning experience with VR-IOMS

Trial Safety

Trial Design

3 Treatment Groups

Orientation and Mobility Training with COMS
1 of 3
Orientation and Mobility Training with VR-IOMSs
1 of 3
No Orientation and Mobility Training
1 of 3

Active Control

Experimental Treatment

Non-Treatment Group

102 Total Participants · 3 Treatment Groups

Primary Treatment: Orientation and Mobility Training with VR-IOMSs · Has Placebo Group · N/A

Orientation and Mobility Training with VR-IOMSs
Behavioral
Experimental Group · 1 Intervention: Orientation and Mobility Training with VR-IOMSs · Intervention Types: Behavioral
No Orientation and Mobility Training
Behavioral
PlaceboComparator Group · 1 Intervention: No Orientation and Mobility Training · Intervention Types: Behavioral
Orientation and Mobility Training with COMS
Behavioral
ActiveComparator Group · 1 Intervention: Orientation and Mobility Training with COMS · Intervention Types: Behavioral

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: within 30 minutes after completion of vr-ioms training

Who is running the clinical trial?

University of Alabama at BirminghamLead Sponsor
1,421 Previous Clinical Trials
2,217,746 Total Patients Enrolled
7 Trials studying Vision, Low
724 Patients Enrolled for Vision, Low
Lei Liu, PhDPrincipal InvestigatorUniversity of Alabama at Birmingham
1 Previous Clinical Trials
35 Total Patients Enrolled
1 Trials studying Vision, Low
35 Patients Enrolled for Vision, Low

Eligibility Criteria

Age Any Age · All Participants · 10 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
You have a best corrected visual acuity of 20/650 or worse.
You have central vision loss, you have a radius of field of 50-80 degrees.
You have a visual impairment that prevents you from completing the NLPT or TGJ.
Potential participants will be taken to real streets by COMS and their performance on the 3 studied tasks will be evaluated.
Visual acuity 20/15-20/100, radius of field 5-55 deg.
You have sufficient functional vision to learn the O&M tasks (evaluated by COMS in real streets).

About The Reviewer

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 31st, 2021

Last Reviewed: November 29th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.