High Definition tDCS and rehabilitation for Spinal Cord Injury

University of Texas Rio Grande Valley, Harlingen, TX
Spinal Cord Injury+1 More ConditionsHigh-definition Transcranial Direct Current Stimulation - Device
Eligibility
18 - 75
All Sexes

Study Summary

This trial looks to improve upper limb recovery in people with SCI through the use of tDCS. It will explore how current delivery impacts functional benefit. Results could help in clinical settings.

Eligible Conditions
  • Spinal Cord Injury
  • Spinal Cord Disease

Treatment Effectiveness

Study Objectives

2 Primary · 2 Secondary · Reporting Duration: Collected four times during study duration: (Baseline-phase) Day 1 and 14; (Post-Rehabilitation-phase) Day 1 and 14

Day 1
Electromyography
Congenital retrognathism
Graded Redefined Assessment of Strength, Sensibility, and Prehension (GRASSP)
Maximum Volitional Contraction (MVC)

Trial Safety

Awards & Highlights

No Placebo Group
All patients enrolled in this trial will receive the new treatment.

Trial Design

2 Treatment Groups

Conventional tDCS and rehabilitation
1 of 2
High Definition tDCS and rehabilitation
1 of 2

Active Control

Experimental Treatment

24 Total Participants · 2 Treatment Groups

Primary Treatment: High Definition tDCS and rehabilitation · No Placebo Group · N/A

High Definition tDCS and rehabilitation
Device
Experimental Group · 1 Intervention: High-definition Transcranial Direct Current Stimulation · Intervention Types: Device
Conventional tDCS and rehabilitation
Device
ActiveComparator Group · 1 Intervention: Conventional Transcranial Direct Current Stimulation · Intervention Types: Device

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: collected four times during study duration: (baseline-phase) day 1 and 14; (post-rehabilitation-phase) day 1 and 14

Who is running the clinical trial?

University of Texas Rio Grande ValleyLead Sponsor
6 Previous Clinical Trials
2,704 Total Patients Enrolled
Kelsey Baker, PhDPrincipal InvestigatorUniversity of Texas Rio Grande Valley

Eligibility Criteria

Age 18 - 75 · All Participants · 3 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
You have an incomplete spinal cord injury or lesion in your neck as diagnosed by a doctor.
You had a spinal cord injury at least 18 months ago.
Your injury or affected area is between the second cervical vertebra and the first thoracic vertebra.

Frequently Asked Questions

Is participation in this trial restricted to octogenarians or can those under 85 years of age enroll?

"Participants that are eligible to join this experiment must be in the 18-75 age bracket. In addition, there is a specific selection of 37 studies for minors and another 334 trials dedicated to persons over 65 years old." - Anonymous Online Contributor

Unverified Answer

Is this study currently enrolling participants?

"Affirmative. Data provided on clinicaltrials.gov verifies that this medical trial, first posted on November 23rd 2020 is actively enrolling candidates. 24 participants are needed from one single site for the study to proceed." - Anonymous Online Contributor

Unverified Answer

How can I become eligible to partake in this experiment?

"This scientific trial is seeking 24 individuals aged 18-75, with a spinal cord affliction. Eligible participants must have tricep strength of at least MRC grade 2 and be 1 muscle grade weaker than their biceps; additionally they should generate an active motor evoked potential >200 uV via transcranial magnetic stimulation. Furthermore, each subject will need to provide signed and dated informed consent as well as demonstrate that their iSCI happened no less than 18 months ago. Bicep muscles are required to register ≥3 on the Medical Research Council (MRC) scale, signify willingness to take part in all research procedures for" - Anonymous Online Contributor

Unverified Answer

To what extent has enrollment been completed for this medical investigation?

"Affirmative. As evidenced on clinicaltrials.gov, this medical experiment is actively recruiting participants with the trial being posted initially on November 23rd 2020 and most recently updated October 17th 2022. The 24 needed patients will be found at a single centre of care." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.