Peripheral Nerve Block for Ankle Fractures

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
MaineGeneral Medical Center, Augusta, ME
Ankle Fractures+3 More
Peripheral Nerve Block - Procedure
Eligibility
18+
All Sexes
What conditions do you have?
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Study Summary

Surgical treatment for patients with a fracture of the ankle or distal radius is commonly offered on an outpatient basis. Patients are routinely discharged from hospital within 4 hours of their procedure. The surgery is commonly performed under peripheral nerve block with sedation, or under general anesthesia with postoperative peripheral nerve block, (if required for analgesic purposes). It is unclear which of these two strategies offers patients superior pain relief in the first few days following surgery. This trial aims to compare the pain intensity and analgesic medication consumption between patients in these two groups.

Eligible Conditions

  • Ankle Fractures
  • Radius Fracture Distal

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

1 Primary · 5 Secondary · Reporting Duration: 24 hours, 48 hours, 72 hours postop

12 hours postop
Pain 12 hours
24 hours postop
Nausea and Vomiting 24 hours
Pain 24 hours
Pain Functional Activity Scale 24 hours
Hour 72
Analgesic consumption
48 hours postop
Pain 48 hours
Pain Functional Activity Scale 48 hours
First 72 hours postop
Rebound pain

Trial Safety

Safety Progress

1 of 3

Trial Design

2 Treatment Groups

Peripheral Nerve Block
1 of 2
General Anesthesia +/- PNB
1 of 2
Active Control

160 Total Participants · 2 Treatment Groups

Primary Treatment: Peripheral Nerve Block · No Placebo Group · N/A

Peripheral Nerve Block
Procedure
ActiveComparator Group · 1 Intervention: Peripheral Nerve Block · Intervention Types: Procedure
General Anesthesia +/- PNB
Procedure
ActiveComparator Group · 1 Intervention: Peripheral Nerve Block · Intervention Types: Procedure

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: 24 hours, 48 hours, 72 hours postop

Trial Background

Stuart A Aitken, Principal Investigator
Principal Investigator
MaineGeneral Health
Closest Location: MaineGeneral Medical Center · Augusta, ME
2012First Recorded Clinical Trial
1 TrialsResearching Ankle Fractures
2 CompletedClinical Trials

Eligibility Criteria

Age 18+ · All Participants · 3 Total Inclusion Criteria

Mark “yes” if the following statements are true for you:
You have an isolated fracture requiring surgery.

About The Reviewer

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 9th, 2021

Last Reviewed: August 12th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.

References