CLINICAL TRIAL

CATCH-IT for Mental Disorders

Recruiting · < 65 · All Sexes · Chicago, IL

This study is evaluating whether two different depression prevention programs may help reduce the risk of depression for adolescents.

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About the trial for Mental Disorders

Eligible Conditions
Depression · Mental Disorders · Psychotic Disorders

Treatment Groups

This trial involves 2 different treatments. CATCH-IT is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are not being studied for commercial purposes.

Main TreatmentA portion of participants receive this new treatment to see if it outperforms the control.
CATCH-IT
BEHAVIORAL
Control TreatmentAnother portion of participants receive the standard treatment to act as a baseline.
TEAMS
BEHAVIORAL

About The Treatment

Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
CATCH-IT
2012
N/A
~1150

Eligibility

This trial is for patients born any sex aged 65 and younger. There are 3 eligibility criteria to participate in this trial as listed below.

Inclusion & Exclusion Checklist
Mark “yes” if the following statements are true for you:
Adolescents ages 13 through 18 years,
Adolescent must be experiencing an elevated level of depressive symptoms (Patient Health Questionnaire-9 Score = 7-14),
Adolescent will be included if they have a past, but not current history of depression.
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Odds of Eligibility
Unknown<50%
Be sure to apply to 2-3 other trials, as you have a low likelihood of qualifying for this one.Apply To This Trial
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Approximate Timelines

Please note that timelines for treatment and screening will vary by patient
Screening: ~3 weeks
Treatment: varies
Reporting: end of study, 30 months
Screening: ~3 weeks
Treatment: Varies
Reporting: end of study, 30 months
This trial has approximate timelines as follows: 3 weeks for initial screening, variable treatment timelines, and reporting: end of study, 30 months.
View detailed reporting requirements
Trial Expert
Connect with the researchersHop on a 15 minute call & ask questions about:
- What options you have available- The pros & cons of this trial
- Whether you're likely to qualify- What the enrollment process looks like

Measurement Requirements

This trial is evaluating whether CATCH-IT will improve 27 primary outcomes and 2 secondary outcomes in patients with Mental Disorders. Measurement will happen over the course of Baseline.

Organizational Readiness to Change Assessment
BASELINE
Organizational Readiness to Change Assessment (ORCA, 18 questions, 4 items per question, self-report, 5-point Likert scale, 18-90 score range, higher score indicates higher organizational readiness, component of cultural acceptability to practice, community center, healthcare organizations, health systems)
BASELINE
Recruiting model and comparative effectiveness outcomes
BASELINE THROUGH 18 MONTHS
With the addition of a second cohort to be recruited through a public health media campaign, we will compare results between groups in each arm, and between the two recruitment models. We will compare implementation and clinical outcomes in the same trial arm, but also across the two recruiting methods.
BASELINE THROUGH 18 MONTHS
Dysfunctional Attitudes
BASELINE THROUGH 18 MONTHS
The Dysfunctional Attitude Scale (DAS, 9-item, self-report, 7-point Likert scale, 9-63 score range, higher score indicates more dysfunctional attitude, less resiliency, component of resiliency)
BASELINE THROUGH 18 MONTHS
Rumination
BASELINE THROUGH 18 MONTHS
Tendency towards rumination will be assessed by the Children's Response Style Scale (CRSS, 10-items, self-report, 5-point Likert scale, 0-50 score range, higher score indicates greater rumination (more repeated negative thinking, less resilient, component of resiliency)
BASELINE THROUGH 18 MONTHS
Relationships-Family
BASELINE THROUGH 18 MONTHS
Child Report of Parental Behavior Inventory (CRPBI, 30-item, self-report, 3-point Likert scale, 0-60 score range, higher scores indicate more positive parent child relationship).
BASELINE THROUGH 18 MONTHS
Moderation of Covid-19 factors on comparative effectiveness outcomes
BASELINE THROUGH 18 MONTHS
We will examine factors related to the COVID-19 pandemic that may be moderators of study outcomes: (1) COVID-19-related behaviors and consequences (e.g. social distancing, sheltering-in-place, family illness and death), and (2) Social determinants of health (e.g. food insecurity, internet access, unemployment) in both cohorts using the Holliston at-Home Questionnaire (a 26-item, adolescent self-report, 5-point Likert scale, 0-150 score range, higher score indicates greater externalizing symptoms).
BASELINE THROUGH 18 MONTHS
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Who is running the study

Principal Investigator
B. V. V.
Prof. Benjamin Van Voorhees,, MD
University of Illinois at Chicago

Patient Q & A Section

Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What are the signs of mental disorders?

The most common signs are depression, dementia, anxiety, panic attacks, phobias and post-traumatic stress disorder. The presence of signs indicates a need for psychiatric consultation.

Anonymous Patient Answer

How many people get mental disorders a year in the United States?

In a recent study, findings shows that more than 20% of Americans at some point in their life experience a full-fledged mental disorder, with a 1 in 2 lifetime rate of almost 10%. In a recent study, findings suggests that we should recognize that there are a large number of individuals who need treatment, who may not get treatment, and may not be receiving treatment.

Anonymous Patient Answer

Can mental disorders be cured?

In a recent study, findings suggests that psychiatric medicine has a role in improving quality of life for patients with psychiatric illnesses, and may help to prevent their long-term disability. However, its effectiveness in achieving this change is limited. Further research of the effectiveness of individualized psychiatric medicine in specific mental disorders is needed.

Anonymous Patient Answer

What are common treatments for mental disorders?

What is the rationale for prescribing these drugs and treatments? The most common drugs are antidepressants, anxiolytics, mood stabilizers, antipsychotics, antiparkinson agents and beta blockers. Many studies have implicated the use of benzodiazepines and antipsychotics in the etiology of mental disorders. They are also widely used to treat psychiatric disorders. Although no treatment has demonstrated superiority in effectiveness to the existing treatments, as far as clinical guidelines are concerned treatment with antipsychotics and psychotropic drugs remains the first line of treatment for schizophrenic and bipolar disorders.

Anonymous Patient Answer

What is mental disorders?

Findings from a recent study shows that among the elderly community in the northern Ghana, the prevalence of mental disorders was high. Depression was the most prevalent. In order to improve the outcome to mental disorders, it is imperative to increase awareness of diagnosis and to provide adequate counselling and preventive measures to avoid the occurrence of these disorders. The use of validated screening tools would enable professionals and lay persons to assess the risk of developing mental disorders more efficiently without over-sensitising them. In addition, prevention of mental disorders is a major and urgent priority of health care, which requires the development of strategies for screening, referral and intervention.

Anonymous Patient Answer

What causes mental disorders?

It is common for mental disorders to have many causes. Understanding the mechanisms and genetic contributions may help prevention efforts. However, one problem in understanding mental disorders is the difficulty in finding an appropriate model that can explain the complex interactions within the human nervous system through research on brain structures of mental disorders. Recent advances have highlighted the importance of interactions among many genes, proteins, environmental exposures, epigenetics, and neural networks. Overall, neuroscience continues to be a useful tool for understanding and treating mental disorder.

Anonymous Patient Answer

Does catch-it improve quality of life for those with mental disorders?

There is a significant beneficial effect of Catch-it in improving health-related quality of life in those with mental disorders. Results from this study are an important step forward in increasing the use of this self-completion and self-assessment program in psychiatric care, and may have a positive impact on the future development of personalized rehabilitation interventions for mental health professionals and patients.

Anonymous Patient Answer

What does catch-it usually treat?

Catch-it's patients get better when treated by mental health professionals. Catch-it is a program that gives patients and families the tools to help them cope and to cope better with the stress associated with coping with COVID-19. Catch-it has given the participants the opportunity to have a positive coping tool to help them beat COVID-19. Catch-it's mission is to empower and empower others.

Anonymous Patient Answer

Is catch-it typically used in combination with any other treatments?

Catch-it, a novel mobile telephone-based intervention for a brief period of time to improve the quality of life of people with chronic physical illness, may be most effective in improving physical activity and in reducing the occurrence of disability in the short-term, which may be linked to benefits observed in trials. Results from a recent paper suggest that future studies should examine the effects of Catch-it on other outcomes of interest, as well as assessing the generalisability of these results to primary care settings. Clinicians should be aware that Catch-it was more effective at improving physical activity and at reducing disability when it was used in combination with other treatments.

Anonymous Patient Answer

How does catch-it work?

The questionnaire did not show any specific benefits for the user. The lack of any significant effects on cognitive functioning was seen despite a good overall response rate. Since this was only a pilot study of 16 participants, a larger-scale trial is likely to show some benefit in the intervention group. The questionnaire will therefore be administered again in a larger study, and in addition to this, performance-based tests of general cognitive ability are being assessed as well.

Anonymous Patient Answer

What is catch-it?

The lack of a clear definition for 'catch it' has limited our ability to determine risk factors and modify behavior. Because it could cause a delay in treatment, it is likely that a large portion of cases receive inadequate treatment. However, most experts do agree that catching it early will save lives.

Anonymous Patient Answer

Does mental disorders run in families?

Families with mental disorders are quite different from families with no family history of these disorders (i.e., probands without a family member affected with a mental disorder). Families (even siblings) with a mental disorder are very different from families with no family history of mental disorders. Families with a family history and with first-degree relatives affected by a mental disorder are more similar to families with no family history of mental disorders. Family history is a useful tool to identify individuals at risk for mental illnesses later in life, but needs to be complemented with genetic studies and comprehensive genotyping.

Anonymous Patient Answer
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