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Depression Prevention Programs for Adolescents (P2P Trial)

N/A

Recruiting

Led By Tracy RG Gladstone, PhD

Research Sponsored by University of Illinois at Chicago

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be younger than 65 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up end of study, 30 months

Awards & highlights

P2P Trial Summary

This trial will compare the effectiveness of two different depression prevention programs to see which is better at preventing depressive illness in adolescents. The trial will also assess the participants', parents', and providers' experiences with each intervention approach.

Who is the study for?

This trial is for teens aged 13-19 with a history of depression but not currently depressed, showing elevated depressive symptoms without severe drug/alcohol abuse or high-risk psychiatric conditions. They shouldn't be on recent medication for mood disorders or engaged in cognitive therapy.Check my eligibility

What is being tested?

The PATH 2 Purpose study compares two programs: CATCH-IT and TEAMS, aimed at preventing depression among adolescents. Participants are randomly assigned to one of the interventions across various locations, assessing their effectiveness and experiences during COVID-19.See study design

What are the potential side effects?

Since CATCH-IT and TEAMS are psychological interventions rather than medications, they may cause emotional discomfort or stress due to discussing personal issues but typically do not have physical side effects like drugs.

P2P Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ end of study, 30 months

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~end of study, 30 months

This trial's timeline: 3 weeks for screening, Varies for treatment, and end of study, 30 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Acceptability of Intervention

Anxiety Symptoms

Blood Pressure

+24 more

Secondary outcome measures

Implementation themes

Moderation of Covid-19 factors on comparative effectiveness outcomes

P2P Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: CATCH-ITExperimental Treatment1 Intervention

Competent Adulthood Transition with Cognitive-behavioral & Interpersonal Training (CATCH-IT) is an internet-based depression prevention program that targets decreasing modifiable risk factors while enhancing protective factors in at-risk adolescents, and that includes a parent program. It has been shown to be safe, feasible, and efficacious.

Group II: TEAMSActive Control1 Intervention

Teens Achieving Mastery over Stress (TEAMS) is an 8-session group depression prevention program teaching teens how to deal with stress and negative moods, and ways to manage low mood based on cognitive-behavioral therapy (CBT) principles and strategies. Efficacy has been demonstrated by several trials over time.

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

CATCH-IT

2020

N/A

~1170

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

University of Illinois College of Medicine RockfordOTHER

1 Previous Clinical Trials

44 Total Patients Enrolled

Wellesley CollegeOTHER

4 Previous Clinical Trials

2,386 Total Patients Enrolled

4 Trials studying Depression

2,386 Patients Enrolled for Depression

Advocate Health CareOTHER

53 Previous Clinical Trials

1,510,317 Total Patients Enrolled

2 Trials studying Depression

1,542 Patients Enrolled for Depression

Media Library

CATCH-IT Clinical Trial Eligibility Overview. Trial Name: NCT04290754 — N/A

Depression Research Study Groups: TEAMS, CATCH-IT

Depression Clinical Trial 2023: CATCH-IT Highlights & Side Effects. Trial Name: NCT04290754 — N/A

CATCH-IT 2023 Treatment Timeline for Medical Study. Trial Name: NCT04290754 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is this trial currently recruiting participants?

"Affirmative. The clinical trial database says that this medical experiment is actively recruiting participants, with the original post published on January 1st 2020 and most recently edited June 28th 2022. 664 volunteers are necessary from just a single site."

Answered by AI

Is this experiment extending its parameters to include elderly individuals?

"According to the requirements, anyone between 13 and 19 years old is eligible for this trial. Moreover, there are currently 279 clinical trials just for minors and 1086 studies targeting adults over 65."

Answered by AI

What is the aggregate amount of individuals engaging in this research?

"Affirmative. According to clinicaltrials.gov, this investigation is actively recruiting its participants. It was first made available on January 1st 2020 and has been updated most recently on June 28th 2022. The trial necessitates 664 subjects at one location for completion."

Answered by AI

Am I eligible to participate in this research project?

"This research project is searching for 664 adolescents, aged 13-19 years old, who are currently coping with depression. The selection criteria requires that they exhibit elevated levels of depressive symptoms (as indicated by a Patient Health Questionnaire-9 Score between 5 and 18), as well as having had prior experience with the illness but not be actively exhibiting it right now."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

PATH 2 Purpose: Primary Care and Community-Based Prevention of Mental Disorders in Adolescents

Benjamin Van Voorhees, MD, MPH 2020. "PATH 2 Purpose: Primary Care and Community-Based Prevention of Mental Disorders in Adolescents". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04290754.

All > Mental Illness