← Back to Search

Physical Therapy for Back Pain

N/A

Waitlist Available

Led By Sarah E. Gullbrand, PhD

Research Sponsored by VA Office of Research and Development

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

acute kidney injury

chronic severe kidney disease

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 0 to 6 weeks

Awards & highlights

Study Summary

This trial is testing if physical therapy can help improve back pain by measuring changes in the spinal discs.

Who is the study for?

This trial is for individuals with back pain or degenerative disc disease who are stable enough for physical therapy. They must not have had prior spinal surgery, and should be free of metal implants, severe kidney issues, or allergies to MRI contrast. Pregnant individuals and those with certain electronic devices like pacemakers cannot participate.Check my eligibility

What is being tested?

The study is looking at how physical therapy affects the spinal discs in patients with back pain by using MRI scans to see if changes in the spine can predict improvement from the therapy.See study design

What are the potential side effects?

Physical therapy may cause temporary soreness or discomfort in some patients as they perform exercises designed to improve their condition.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I have sudden kidney damage.

Select...

I have a long-term severe kidney problem.

Select...

My body has trouble removing certain MRI contrast dyes.

Select...

I have kidney problems that existed before my current treatment.

Select...

I have low back pain that limits my activities.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 0 to 6 weeks

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~0 to 6 weeks

This trial's timeline: 3 weeks for screening, Varies for treatment, and 0 to 6 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Change in Disc T1 relaxation time

Change in Disc T2 relaxation time

Change in Lumbar Range of Motion

+2 more

Trial Design

1Treatment groups

Experimental Treatment

Group I: Physical therapyExperimental Treatment1 Intervention

Subjects will be prescribed a 6-week physical therapy regimen consisting of one 45 minute in office visit per week, and home exercises performed daily. The in-office visits with a physical therapy provider will consist of the application of manual therapy, particularly high-velocity, low amplitude thrust mobilization in the anterior/posterior direction of the lumbar spine. In office visits will also include supervised repeated motion of the lumbar spine into extension (McKenzie therapy, 3 sets of 10 repetitions, in prone and standing positions) Patients will be instructed to complete these repeated extension exercises at home daily for the 6 week period.

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Physical Therapy

2020

Completed Phase 4

~1460

0 / 5Eligibility criteria met

Find a Location

Who is running the clinical trial?

VA Office of Research and DevelopmentLead Sponsor

1,609 Previous Clinical Trials

3,306,588 Total Patients Enrolled

Sarah E. Gullbrand, PhDPrincipal InvestigatorCorporal Michael J. Crescenz VA Medical Center, Philadelphia, PA

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is participation in this research restricted to those aged 65 years or older?

"This clinical trial only permits patients between the ages of 30 and 70 to take part. However, there are 10 studies for minors below 18 years old as well as 276 trials for individuals above 65."

Answered by AI

Is enrollment still available for this experiment?

"Based on the clinicaltrials.gov database, this particular study is no longer accepting patients as it was last edited in May of 2022. However, there are currently 339 other trials actively enrolling participants."

Answered by AI

Am I eligible to participate in this clinical trial?

"This trial is seeking 15 adult participants between the ages of 30 and 70 who suffer from lower back pain. To be eligible, individuals must meet these requirements: Qualify for physical therapy, Present with or without distal-buttock discomfort, Have a current activity that limits their low back ache, Possess symptoms lasting any duration."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

The Role of Disc Nutrition in the Etiology and Clinical Treatment of Disc Degeneration

2024. "The Role of Disc Nutrition in the Etiology and Clinical Treatment of Disc Degeneration". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04134910.

All > Chronic Back Pain > Degenerative Disc Disease