Partial Sleep Deprivation for Sleep
Trial Summary
What is the purpose of this trial?
The goal of this interventional study is to differentiate the effects of an acute partial sleep deprivation intervention on markers of cardiovascular health, cardio-autonomic function, physical and cognitive performance, as well as overall wellbeing in active vs sedentary individuals. The main aims of the project are: * To differentiate the effects of partial sleep deprivation on central hemodynamics (i.e., central blood pressure and arterial stiffness) in active vs sedentary individuals. * To differentiate the effects of partial sleep deprivation on physical (i.e., handgrip strength and reactive strength index) and cognitive performance (i.e., reaction time and impulse control) in active vs sedentary individuals. * To differentiate the effects of partial sleep deprivation on overall wellbeing (i.e., cardio-autonomic function, inflammation levels, and psychological mood states) in active vs sedentary individuals. Participants will be divided into two groups based on aerobic activity level - active or sedentary - and assessed for markers of cardiovascular health, cardio-autonomic function, physical and cognitive performance, as well as overall wellbeing before and after three days of normal sleep and three days of partially deprived sleep (i.e., 30% reduction in total time in bed).
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications.
What data supports the effectiveness of the treatment Partial Sleep Deprivation for sleep?
Research shows that partial sleep deprivation, where patients are kept awake for part of the night, can significantly reduce symptoms of depression. In several studies, many patients experienced a noticeable improvement in their mood after undergoing this treatment, suggesting it can be an effective short-term therapy for depression.12345
Is partial sleep deprivation safe for humans?
Partial sleep deprivation can lead to negative effects on health, such as impaired cognitive performance, increased fatigue, and potential long-term health issues like cardiovascular disease and diabetes. However, it has been used as a therapy for depression, showing some positive effects, but the safety and impact can vary among individuals.678910
How is partial sleep deprivation treatment different from other sleep treatments?
Partial sleep deprivation is unique because it involves intentionally reducing sleep time, which can temporarily improve mood and alertness, unlike other treatments that aim to increase sleep duration or quality. This approach is different from standard treatments like positive airway pressure (PAP) therapy, which focuses on treating sleep-disordered breathing by maintaining open airways during sleep.1112131415
Eligibility Criteria
This trial is for individuals who are either physically active or sedentary, to study how not getting enough sleep affects heart health, physical and mental performance, and overall wellbeing. Participants will be assessed before and after having normal sleep and then less sleep than usual.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Baseline Assessment
Participants are assessed for markers of cardiovascular health, cardio-autonomic function, physical and cognitive performance, as well as overall wellbeing before the sleep intervention
Intervention
Participants undergo three days of normal sleep followed by three days of partial sleep deprivation (30% reduction in total time in bed)
Post-Intervention Assessment
Participants are assessed immediately and 3 days after the intervention for changes in cardiovascular health, cardio-autonomic function, physical and cognitive performance, and overall wellbeing
Follow-up
Participants are monitored for any long-term effects of the intervention
Treatment Details
Interventions
- Partial Sleep Deprivation
Find a Clinic Near You
Who Is Running the Clinical Trial?
Florida State University
Lead Sponsor