Therapeutic Gloves for Hand Osteoarthritis

Overseen By Brenda Endress, Research Manager, CCRC

Age: 18+

Sex: Any

Trial Phase: Academic

Sponsor: Altoona Center for Clinical Research

Must not be taking: Topical creams, NSAIDs

Disqualifiers: Neurological conditions, Surgical history, Secondary OA, others

Compensation: Varies

Number of Visits: 9

Duration: 9 months

140 Participants Needed

What You Need to Know Before You Apply

What is the purpose of this trial?

The goal of this study is to evaluate change in symptoms using semiconductor embedded gloves for hand osteoarthritis.

Will I have to stop taking my current medications?

The trial does not specify if you need to stop taking your current medications, but you cannot have used topical creams or gels for arthritic pain in the last week.

Are therapeutic gloves for hand osteoarthritis safe to use?

Some medical gloves have been associated with skin irritation, such as dermatitis (skin inflammation), especially if they contain certain chemicals or powders. However, switching to gloves made from different materials, like nitrile, can reduce these issues. It's important to ensure that the gloves meet safety standards to minimize any adverse reactions. ^{1 2 3 4 5}

How is the Semiconductor Embedded Therapeutic Gloves treatment different from other treatments for hand osteoarthritis?

The Semiconductor Embedded Therapeutic Gloves are unique because they integrate sensors directly into the fabric, potentially offering real-time feedback and enhanced comfort compared to traditional arthritis gloves, which mainly provide pressure and warmth. ^{4 6 7 8 9}

What data supports the effectiveness of the treatment Semiconductor Embedded Therapeutic Gloves for hand osteoarthritis?

The research on wearable electronic devices, like the smart contact lens and heat patch for eye inflammation, shows that similar technologies can be effective in providing noninvasive, mobile health care solutions. This suggests that semiconductor technology in therapeutic gloves might also offer benefits for managing hand osteoarthritis by providing targeted therapy and monitoring. ^{10 11 12 13 14}

Are You a Good Fit for This Trial?

This clinical trial is open to individuals suffering from hand osteoarthritis. Specific inclusion and exclusion criteria are not provided but typically involve factors like age range, severity of condition, and absence of certain medical conditions or treatments that could interfere with the study.

Inclusion Criteria

I am willing and able to follow the study's schedule and rules.

I am between 40 and 75 years old.

I have a type of hand arthritis diagnosed by X-rays and meet specific criteria.

Exclusion Criteria

I have a neurological condition like multiple sclerosis or Parkinson's disease.

I've had hand surgery in the past 5 years or injections in the last 6 months.

I currently have an infection.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants receive semiconductor embedded gloves or placebo gloves for hand osteoarthritis

9 months

Weekly visits for 9 months

Follow-up

Participants are monitored for safety and effectiveness after treatment

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

• Semiconductor Embedded Therapeutic Gloves

Trial Overview The study investigates whether wearing semiconductor embedded therapeutic gloves can improve symptoms in patients with hand osteoarthritis compared to non-invasive circulation gloves.

How Is the Trial Designed?

Group I: Semiconductor circulation gloves Active Control 1 Intervention

The gloves will have semiconductors embedded in the fabric.

Group II: Placebo circulation gloves Placebo Group 1 Intervention

The gloves will look identical to the active circulation gloves, but will not have semiconductors embedded into the fabric

Who Is Running the Clinical Trial?

Altoona Center for Clinical Research

Lead Sponsor

Trials

1

Recruited

140+

INCREDIWEAR HOLDINGS, INC.

Industry Sponsor

Trials

6

Recruited

630+

Citations

1. United States pubmed.ncbi.nlm.nih.gov

Smart contact lens and transparent heat patch for remote monitoring and therapy of chronic ocular surface inflammation using mobiles. [2022]

2. United States pubmed.ncbi.nlm.nih.gov

Ultra-Thin Chip Package (UTCP) and stretchable circuit technologies for wearable ECG system. [2020]

3. United States pubmed.ncbi.nlm.nih.gov

Bio-Integrated Wearable Systems: A Comprehensive Review. [2020]

4. Egypt pubmed.ncbi.nlm.nih.gov

Laser additive manufacturing of shape memory biopolymer bone scaffold: 3D conductive network construction and electrically driven mechanism. [2023]

5. United States pubmed.ncbi.nlm.nih.gov

Biocompatible MEMS electrode array for determination of three-dimensional strain. [2020]

6. United States pubmed.ncbi.nlm.nih.gov

Health effects associated with medical glove use. [2019]

7. England pubmed.ncbi.nlm.nih.gov

Compression gloves for patients with hand arthritis (C-GLOVES): A feasibility study. [2023]

8. United States pubmed.ncbi.nlm.nih.gov

The effectiveness of a low-chemical, low-protein medical glove to prevent or reduce dermatological problems. [2016]

9. England pubmed.ncbi.nlm.nih.gov

Protective effect of glove on median nerve compression in the carpal tunnel. [2011]

10. Italy pubmed.ncbi.nlm.nih.gov

[Collateral effects of a project of latex rubber removal in a hospital institution]. [2013]

11. England pubmed.ncbi.nlm.nih.gov

The effects of arthritis gloves on people with Rheumatoid Arthritis or Inflammatory Arthritis with hand pain: a study protocol for a multi-centre randomised controlled trial (the A-GLOVES trial). [2018]

12. United States pubmed.ncbi.nlm.nih.gov

Characterization of a novel data glove based on textile integrated sensors. [2020]

13. England pubmed.ncbi.nlm.nih.gov

Activity problems in everyday life--patients' perspectives of hand osteoarthritis: "try imagining what it would be like having no hands". [2014]

14. Sweden pubmed.ncbi.nlm.nih.gov

Assessment of the effectiveness of a functional splint for osteoarthritis of the trapeziometacarpal joint on the dominant hand: a randomized controlled study. [2014]