PlaySmart Digital Intervention for Preventing Adolescent Opioid Abuse

Recruiting at 14 trial locations

Overseen By Lily Hoerner

Age: < 65

Sex: Any

Trial Phase: Academic

Sponsor: Trustees of Dartmouth College

Disqualifiers: Opioid misuse, others

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: 3

533 Participants Needed

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial tests if a game called PlaySmart can help high-risk teenagers understand the dangers of misusing prescription opioids and illegal drugs like heroin. The game aims to make them more confident in refusing drugs and prevent them from starting to use these substances.

Who Is on the Research Team?

Lynn E Fiellin, MD

Principal Investigator

Director, play2PREVENT Lab & Professor, BDS at Geisel School of Medicine at Dartmouth College

Are You a Good Fit for This Trial?

This trial is for high school students who have not misused opioids but are considered 'high-risk' due to recent use of substances like alcohol, marijuana, or non-opioid drugs. They must be willing to play a game for an hour per session and can give consent (or have it given by a parent/guardian if under 18).

Inclusion Criteria

Participants must preferably be enrolled in their high school's School-Based Health Center

1) preferably be enrolled in their high school's School-Based Health Center;

Participants must report NOT having engaged in any prior opioid misuse

Exclusion Criteria

Failure to meet any of the inclusion criteria.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Intervention

Participants engage in the PlaySmart or control video game intervention

6 weeks

Regular gameplay sessions

Follow-up

Participants are monitored for changes in perception of risk, intentions to misuse opioids, and self-efficacy at multiple time points

12 months

Assessments at 3, 6, and 12 months

What Are the Treatments Tested in This Trial?

Interventions

• PlaySmart
• Video Game Control

Trial Overview The study tests whether the digital intervention PlaySmart can prevent opioid misuse among adolescents compared to a control video game. The effectiveness will be measured after three months based on participants' perceived risk of harm from prescription opioids and heroin/fentanyl.

How Is the Trial Designed?

Group I: PlaySmart Experimental Treatment 1 Intervention

Video game intervention.

Group II: Control Game Experimental Treatment 1 Intervention

Control video game intervention.

Who Is Running the Clinical Trial?

Trustees of Dartmouth College

Lead Sponsor

Trials

32

Recruited

14,500+

Yale University

Lead Sponsor

Trials

1,963

Recruited

3,046,000+

National Institute on Drug Abuse (NIDA)

Collaborator

Trials

2,658

Recruited

3,409,000+