Computer Based Response Training Weight Loss Intervention for Eating Disorders

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Eating Disorders+2 More
Computer Based Response Training Weight Loss Intervention - Behavioral
Eligibility
18 - 65
All Sexes
What conditions do you have?
Select

Study Summary

This trial will test whether a food response training intervention can help people lose body fat and keep it off. The project will also use brain imaging to examine how the intervention works, and whether it can be generalized to other types of food.

Eligible Conditions
  • Eating Disorders
  • Obesity
  • Hyperphagia

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

1 Primary · 14 Secondary · Reporting Duration: Baseline, 1 month, 3 months, 6 months, 12 months

Baseline, 1 month
Change in Participant Ratings of Food Monetary Value
Change in Participant Ratings of Unhealthy Food Palatability
Month 12
Body Fat Change
Alcohol Use Disorder
Change in Body Mass Index
Change in Disinhibited Eating Behavior
Change in Eating Disorder Symptoms
Change in Eating in the Absence of Hunger Behavior
Change in Food Addiction Behavior
Change in Food Craving and Liking Behavior
Change in Heart Rate Variability
Change in Physical Activity
Change in Substance Use Behavior
Change in mean R-Peak Amplitude
Dietary Restraint, Emotional Eating, and External Eating

Trial Safety

Safety Progress

1 of 3

Trial Design

2 Treatment Groups

Control Condition
1 of 2
Experimental Condition
1 of 2
Active Control
Experimental Treatment

180 Total Participants · 2 Treatment Groups

Primary Treatment: Computer Based Response Training Weight Loss Intervention · No Placebo Group · N/A

Experimental Condition
Behavioral
Experimental Group · 1 Intervention: Computer Based Response Training Weight Loss Intervention · Intervention Types: Behavioral
Control Condition
Behavioral
ActiveComparator Group · 1 Intervention: Generic Response Training Control Intervention · Intervention Types: Behavioral

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: baseline, 1 month, 3 months, 6 months, 12 months

Who is running the clinical trial?

Flinders UniversityOTHER
34 Previous Clinical Trials
20,906 Total Patients Enrolled
Oregon Research InstituteLead Sponsor
76 Previous Clinical Trials
58,918 Total Patients Enrolled
8 Trials studying Eating Disorders
4,687 Patients Enrolled for Eating Disorders
University of ExeterOTHER
151 Previous Clinical Trials
1,364,663 Total Patients Enrolled
1 Trials studying Eating Disorders
120 Patients Enrolled for Eating Disorders
Radboud University Medical CenterOTHER
998 Previous Clinical Trials
510,012 Total Patients Enrolled
University of OregonOTHER
65 Previous Clinical Trials
34,246 Total Patients Enrolled
Eric Stice, PhDPrincipal InvestigatorStanford University
10 Previous Clinical Trials
4,666 Total Patients Enrolled
7 Trials studying Eating Disorders
3,419 Patients Enrolled for Eating Disorders

Eligibility Criteria

Age 18 - 65 · All Participants · 1 Total Inclusion Criteria

Mark “yes” if the following statements are true for you:

About The Reviewer

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 17th, 2021

Last Reviewed: October 9th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.