Nutritional Supplement for Healthy Nutrition

Overseen By Adam Gonzalez, PhD

Age: 18 - 65

Sex: Any

Trial Phase: Academic

Sponsor: Athletic Greens International

Must not be taking: Supplements, Alcohol, Smoking, others

Disqualifiers: Cardiovascular, Diabetes, Cancer, others

Approved in 4 Jurisdictions This treatment is already approved in other countries

Compensation: Varies

Number of Visits: Unknown

Duration: 2 weeks

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial aims to evaluate how a new dietary supplement, AG1, can fill nutrient gaps and improve gut health. Researchers will compare the effects of AG1, which contains vitamins, minerals, and probiotics, to a placebo. The trial seeks active men and women who have engaged in resistance training with free weights at least twice a week for over a year. Participants must be in good health and willing to maintain their usual diet and exercise routines. As an unphased trial, this study provides participants the chance to contribute to valuable research on dietary supplements and gut health.

Will I have to stop taking my current medications?

The trial does not specify if you need to stop taking your current medications, but it excludes people using medications or supplements that could affect the study results. It's best to discuss your specific medications with the trial staff.

Is there any evidence suggesting that this trial's treatments are likely to be safe?

Research has shown that AG1, a nutritional supplement, is safe for healthy adults. One study found that participants took AG1 for four weeks without any safety issues, indicating that AG1 is generally well-tolerated in the short term. The supplement is also NSF Certified for Sport®, meaning it has been tested to ensure it contains no banned substances. While research continues, early evidence supports its safety for healthy individuals. ^{1 2 3 4 5}

Why are researchers excited about this trial?

Researchers are excited about AG1 - Nutritional Supplement because it combines a wide range of ingredients, including vitamins, minerals, probiotics, prebiotics, and whole food components, into a single supplement. Unlike traditional supplements that might focus on just one or two nutrients, AG1 provides a comprehensive nutritional foundation. This unique combination may enhance overall health by supporting multiple bodily functions simultaneously. Additionally, the inclusion of whole food ingredients could offer more natural and bioavailable nutrients compared to synthetic alternatives.

What evidence suggests that AG1 - Nutritional Supplement is effective for improving nutrient gaps and the gut microbiome?

This trial will compare AG1, a nutritional supplement, with a placebo. Studies have shown that AG1 can help fill common nutrient gaps and improve gut health. Research indicates that it contains over 75 vitamins, minerals, probiotics, and other beneficial ingredients that support overall wellness. Previous findings suggest that AG1 positively affects digestive health, enhancing the quality of life for those who take it. AG1 is designed to boost energy, strengthen the immune system, and increase nutrient levels even in healthy individuals. Overall, AG1 appears to be a promising option for improving nutrition and gut health. ^{6 7 8 9 10}

Are You a Good Fit for This Trial?

This trial is for active men and women interested in improving their nutrition and gut health. Specific eligibility details are not provided, but typically participants should be healthy with no major medical conditions.

Inclusion Criteria

Willing and able to comply with the study protocol

Be in good health as determined by medical history and routine blood chemistries

Have more than 1 year of resistance training experience (minimum of 2 days per week of resistance training session with free weights)

Exclusion Criteria

Known sensitivity to any ingredient in the test formulations as listed in the product label

I have diabetes or another hormone-related condition.

Any other conditions that, in the opinion of the medical staff, could confound the primary endpoints or place the subject at increased risk of harm if they were to participate

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants receive either the nutritional supplement or placebo for 14 days to assess nutrient gaps and gut microbiome changes

2 weeks

Follow-up

Participants are monitored for safety and effectiveness after treatment

2-4 weeks

What Are the Treatments Tested in This Trial?

Interventions

• AG1 - Nutritional Supplement

Trial Overview The study tests a new dietary supplement called AG1 against a placebo to see if it can improve nutrient levels and gut microbiome health in active adults. It's a small study with only 20 people, randomly assigned to either the supplement or placebo group.

How Is the Trial Designed?

Group I: AG1 - Nutritional Supplement Experimental Treatment 1 Intervention

A foundational nutritional supplement consisting of vitamins, minerals, probiotics, prebiotics, and whole food ingredients

Group II: Placebo Placebo Group 1 Intervention

Maltodextrin + Flavoring

AG1 - Nutritional Supplement is already approved in United States, European Union, Canada for the following indications:

Approved in United States as Athletic Greens for:

• General health and wellness
• Nutritional support

Approved in European Union as AG1 Greens for:

• General health and wellness
• Nutritional support

Approved in Canada as Athletic Greens for:

• General health and wellness
• Nutritional support

Who Is Running the Clinical Trial?

Athletic Greens International

Lead Sponsor

Trials

5

Recruited

230+

Citations

1. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov/articles/PMC11445888/

The effects of AG1® supplementation on the gut ... AG1R can be consumed safely by healthy adults over four weeks with a potential beneficial impact in their digestive symptom quality of life.

2. drinkag1.com drinkag1.com/

AG1 Official | More Than A Greens Powder | Best Price AG1 is a daily foundational nutrition formula designed to support energy, immune defense, gut health, and overall wellness. It contains 75+ vitamins, minerals, ...

3. amazon.com amazon.com/AG1-Greens-Powder-Multivitamin-Gluten-Free/dp/B084GZNKZQ

AG1 Greens Powder Supplement | Improve Gut Health Improve gut health. Multivitamin, probiotic, gluten free, vegan and keto friendly. Shaker & scoop included. 75 vitamins.

4. drinkag1.com drinkag1.com/learn/research/scientific-research

AG1® | Research Studies AG1 Next Gen is clinically shown to fill common nutrient gaps even in healthy eaters. · AG1 Next Gen improves key nutrient levels within 3 months. · AG1 Next Gen ...

5. healthline.com healthline.com/nutrition/athletic-greens-review

AG1 Review: A Dietitian and Health Editor's Take The AG1 powder includes 75 vitamins, minerals, probiotics, whole food-sourced plant compounds, and adaptogens to support energy levels, immune health, gut ...

6. drinkag1.com drinkag1.com/product

AG1® | Product Detail AG1 is certified for quality and safety by NSF International and is NSF Certified for Sport® meaning it does not contain any of the 270+ substances banned by ...

7. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov/39352252/

a randomized, double-blind, placebo-controlled clinical trial Conclusions: AG1R can be consumed safely by healthy adults over four weeks with a potential beneficial impact in their digestive symptom quality ...

8. drinkag1.com drinkag1.com/about-ag1/ingredients/ctr

75+ High-Quality Ingredients NSF Certified for Sport®, a rigorous third-party certification ensuring AG1 is free from over 280 banned substances, including stimulants, narcotics, diuretics ...

9. mcgill.ca mcgill.ca/oss/article/critical-thinking-health-and-nutrition/you-probably-dont-need-green-ag1-smoothie

You Probably Don't Need that Green AG1 Smoothie The good news with AG1 is that it is NSF certified, meaning that a recognized third party tests the product to make sure the powder really does ...

10. vively.co.uk vively.co.uk/post/is-ag1-and-athletic-greens-actually-healthy

Is AG1 and Athletic Greens actually healthy? - Vively Overall, current science is mixed and preliminary. The best data so far (company-sponsored) show AG1 is safe for healthy adults and likely ...