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Vitamin

Vitamin C for Low Stomach Acid

Phase 1
Recruiting
Research Sponsored by Indiana University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Healthy, young males age 18-30 years with no prior history of gastrointestinal disease or symptoms.
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up five hours
Awards & highlights

Study Summary

This trial is testing whether vitamin C can reduce stomach acid in people who have low stomach acid from taking omeprazole. Everyone in the study will take vitamin C tablets and then the change in stomach acid will be measured.

Who is the study for?
This trial is for healthy young men aged 18-30 with no history of gastrointestinal issues. Participants must not have used antibiotics in the last 3 months, any medications that could affect the study, or be current smokers. Pregnant individuals and those with a significant medical history related to abdominal conditions or surgeries are excluded.Check my eligibility
What is being tested?
The study tests if ascorbic acid (vitamin C) tablets can temporarily lower stomach acidity in people whose low gastric pH has been caused by taking omeprazole, a common medication for acid-related issues.See study design
What are the potential side effects?
Potential side effects may include digestive discomfort or allergic reactions to vitamin C. Omeprazole might cause headaches, nausea, diarrhea, stomach pain, or long-term use could lead to vitamin B12 deficiency.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
Only young, healthy men between 18 and 30 years old with no past stomach or intestinal issues.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~five hours
This trial's timeline: 3 weeks for screening, Varies for treatment, and five hours for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change in gastric pH and duration of gastric pH \status

Side effects data

From 2018 Phase 2 trial • 20 Patients • NCT03148236
10%
Pericarditis
100%
80%
60%
40%
20%
0%
Study treatment Arm
Vitamin C
Placebo

Trial Design

1Treatment groups
Experimental Treatment
Group I: Experimental: omeprazole and ascorbic acidExperimental Treatment2 Interventions
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Vitamin C
2017
Completed Phase 4
~18470
Omeprazole 20mg
2010
Completed Phase 4
~630

Find a Location

Logistics

Participation is compensated

You will be compensated for participating in this trial.

Who is running the clinical trial?

Hala FaddaUNKNOWN
Butler UniversityUNKNOWN
Indiana UniversityLead Sponsor
976 Previous Clinical Trials
983,343 Total Patients Enrolled

Media Library

Vitamin C (Vitamin) Clinical Trial Eligibility Overview. Trial Name: NCT04199624 — Phase 1
Low Stomach Acid Research Study Groups: Experimental: omeprazole and ascorbic acid
Low Stomach Acid Clinical Trial 2023: Vitamin C Highlights & Side Effects. Trial Name: NCT04199624 — Phase 1
Vitamin C (Vitamin) 2023 Treatment Timeline for Medical Study. Trial Name: NCT04199624 — Phase 1

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Does the eligibility of this trial extend to individuals under 40 years old?

"The eligibility for this clinical investigation requires that all participants are between 18 and 30 years old."

Answered by AI

Is there still an opportunity for volunteers to participate in this research project?

"Correct. According to clinicaltrials.gov, this medical assessment is still recruiting candidates and was initially released on the 1st of October 2021. The trial necessitates 10 participants from a single site."

Answered by AI

Is there a governmental endorsement for the consumption of Vitamin C?

"Vitamin C's safety was estimated to be a 1 in this evaluation, as there is only limited evidence confirming its efficacy and protective characteristics."

Answered by AI

What are the prosaic applications of Vitamin C?

"Catarrh, a vitamin deficiency, and the subsequent supplementation therapy can all be ameliorated by Vitamin C."

Answered by AI

What is the current count of participants in this clinical experiment?

"That is correct. Details published on clinicaltrials.gov demonstrate that the trial, which was first posted in October 2021, is actively recruiting participants. To fulfill their study requirements they need 10 patients from a single site."

Answered by AI

Does my profile meet the criteria to qualify for this research?

"The aim of this trial is to assemble a cohort of 10 young and healthy males, aged between 18-30 years old with no prior record of GI disorders or symptoms. The primary trait being sought is hypochlorhydria."

Answered by AI
~3 spots leftby Mar 2025