Kawasaki MATCH Tool for Kawasaki Disease
(MATCH Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial tests a tool called Kawasaki MATCH to determine if it aids doctors in making better decisions when treating children with Kawasaki Disease or similar illnesses in the emergency room. The trial will compare two groups: one where doctors use the Kawasaki MATCH tool and another where they follow their usual care practices. Children with a fever for at least three days and symptoms like rash or swollen lymph nodes may be suitable candidates. This trial could enhance the identification and management of Kawasaki Disease in hospitals. As an unphased trial, it offers a unique opportunity to advance emergency care for children.
What prior data suggests that this tool is safe for evaluating febrile patients with Kawasaki Disease?
This trial focuses on the Kawasaki MATCH tool, a computer program that aids doctors in making better decisions when treating children with Kawasaki Disease. As a decision-support tool, it does not involve administering new medicine to patients, eliminating direct safety concerns. The tool assists doctors in assessing and managing the condition more effectively. Consequently, there are no reports of side effects or adverse events, as the tool does not physically interact with patients.
Why are researchers excited about this trial?
Researchers are excited about the Kawasaki MATCH tool because it offers a new approach to managing Kawasaki Disease. Unlike standard treatments that rely on traditional diagnostic and management methods, the Kawasaki MATCH tool is a decision support system designed to assist healthcare providers in the Emergency Department. This tool aims to enhance the evaluation and management process by integrating clinical data and evidence-based guidelines, potentially leading to quicker and more accurate diagnoses. By improving decision-making at the point of care, the Kawasaki MATCH tool could optimize patient outcomes and streamline treatment protocols for Kawasaki Disease.
What evidence suggests that the Kawasaki MATCH tool is effective for evaluating febrile patients with Kawasaki Disease?
Research has shown that the Kawasaki MATCH tool, which employs advanced computer technology, effectively diagnoses Kawasaki Disease. It aids doctors in distinguishing Kawasaki Disease from other fever-causing illnesses. Studies have demonstrated that this tool uses common tests, like blood and urine tests, to make accurate predictions. One study found that the tool employs a special method called XGBoost to enhance the reliability of these predictions. Previous research has tested this tool, proving that it can assist doctors in making better decisions. In this trial, some providers will be encouraged to use the Kawasaki MATCH tool, while others will manage patients according to routine care without additional decision support. Overall, strong evidence supports the Kawasaki MATCH tool's effectiveness in diagnosing Kawasaki Disease.12345
Are You a Good Fit for This Trial?
This trial is for patients with a fever who might have Kawasaki Disease (KD) or other non-KD illnesses. Specific eligibility criteria are not provided, so it's best to contact the study team for details on who can participate.Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Providers are randomized to either use the Kawasaki MATCH decision support tool or follow routine care practices
Follow-up
Participants are monitored for safety and effectiveness after treatment, including ED return visits and additional interventions
What Are the Treatments Tested in This Trial?
Interventions
- Kawasaki MATCH
Trial Overview
The trial is testing 'Kawasaki MATCH,' a machine-learning tool designed to help healthcare providers determine if febrile patients have KD or another illness. It aims to see if this tool changes how doctors make decisions.
How Is the Trial Designed?
2
Treatment groups
Experimental Treatment
Active Control
Providers encouraged to access and utilize the Kawasaki MATCH decision support tool when evaluating and managing patients in the Emergency Department
Providers prompted to manage patients as per usual/routine care without additional decision support.
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of California, San Diego
Lead Sponsor
Gordon and Marilyn Macklin Foundation
Collaborator
Rady Children's Hospital, San Diego
Collaborator
Citations
Study Details | NCT07291245 | Kawasaki MATCH Trial
Kawasaki MATCH is a previously validated machine-learning decision support tool for the diagnosis of Kawasaki Disease. This tool utilizes ...
A Multi-Stage Framework for Kawasaki Disease Prediction ...
The intended clinical application of this study is a decision-support tool that leverages routine laboratory tests (blood and urine analyses) ...
An interpretable machine learning-assisted diagnostic ...
A classification tool for differentiation of Kawasaki disease from other febrile illnesses. ... An optimized XGBoost based diagnostic system for ...
Implementation of KIDMATCH: A Clinical Decision Support ...
We developed and validated the KawasakI Disease vs Multisystem InflAmmaTory syndrome in CHildren (KIDMATCH) clinical decision support tool for screening ...
Accuracy of Machine Learning in Discriminating Kawasaki ...
Machine learning has been widely adopted in biomedical research, with numerous studies demonstrating its utility in predicting disease outcomes and informing ...
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