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Behavioral Intervention

Mindfulness App Training for Heart Disease (MATCH Trial)

N/A

Recruiting

Led By Thomas W Kamarck, PhD

Research Sponsored by University of Pittsburgh

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Age 45 years or older

Diagnosed with hypertension by medical provider or clinic blood pressure reading between 125/75 - 149/99

Timeline

Screening 3 weeks

Treatment Varies

Follow Up change in clinic blood pressure assessed with 2 pre-intervention assessments and 2 3-month follow-up assessments (average of 19 weeks)

Awards & highlights

MATCH Trial Summary

This trial will test if mindfulness training, delivered via smartphone, can help reduce stress in midlife & older people at risk of heart disease.

Who is the study for?

Adults aged 45+ in the Pittsburgh area with hypertension and moderate-to-high cardiovascular risk are eligible. They must have a compatible smartphone, speak English well, and be available for study visits. Excluded are those with severe heart conditions, night shift workers, heavy drinkers or drug users, pregnant women, individuals with certain mental health issues or who practice mind-body exercises regularly.Check my eligibility

What is being tested?

The trial is testing if using a mindfulness app can help stressed adults at risk of heart disease. Half will use the app daily for four weeks; the other half won't change their routine. Stress levels will be measured before and after intervention and again three months later using lab visits and wearable devices.See study design

What are the potential side effects?

Since this trial involves mindfulness training through an app rather than medication or invasive procedures, significant side effects aren't expected. However, participants may experience changes in stress levels which could affect mood and behavior.

MATCH Trial Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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I am 45 years old or older.

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I have been diagnosed with high blood pressure.

MATCH Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ change in clinic blood pressure assessed with 2 pre-intervention assessments and 2 3-month follow-up assessments (average of 19 weeks)

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~change in clinic blood pressure assessed with 2 pre-intervention assessments and 2 3-month follow-up assessments (average of 19 weeks)

This trial's timeline: 3 weeks for screening, Varies for treatment, and change in clinic blood pressure assessed with 2 pre-intervention assessments and 2 3-month follow-up assessments (average of 19 weeks) for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Acceptability: Study Burden

Acceptability: Treatment Expectancies

Change In Systolic Blood Pressure Response to Momentary Psychosocial Stress from pre-intervention to 3-month follow-up

+11 more

Secondary outcome measures

Change in Anxiety Symptoms from pre-intervention to 3-month follow-up

Change in Anxiety Symptoms from pre-intervention to post-intervention

Change in Blood Pressure Reactivity to Acute Stress from pre-intervention to post-intervention

+25 more

Other outcome measures

Change in Daily Distress Tolerance

Change in Daily Life Mindfulness

Change in Daily Loneliness

+24 more

MATCH Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: Mindfulness TrainingExperimental Treatment1 Intervention

Mindfulness intervention involving 28 audio-guided lessons plus daily brief practice prompts. Lessons train meditation techniques for 3 mindfulness skills: concentration, sensory clarity, and equanimity. Practice prompts delivered 3x daily build on the skills trained in each lesson.

Group II: Enhanced Usual Care (EUC)Active Control1 Intervention

Participants in the EUC condition will have no study requirements during the 4-week intervention period, but they will receive a list of stress management resources upon randomization (websites, books, health tracking apps, and mental health services) with no additional intervention support.

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Mindfulness Training

2018

Completed Phase 2

~2090

0 / 2Eligibility criteria met

Find a Location

Who is running the clinical trial?

University of PittsburghLead Sponsor

1,722 Previous Clinical Trials

16,342,796 Total Patients Enrolled

4 Trials studying Mindfulness

8,522 Patients Enrolled for Mindfulness

National Heart, Lung, and Blood Institute (NHLBI)NIH

3,838 Previous Clinical Trials

47,851,504 Total Patients Enrolled

Thomas W Kamarck, PhDPrincipal InvestigatorUniversity of Pittsburgh

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is the recruitment of participants for this clinical trial ongoing?

"Per the information found on clinicaltrials.gov, this study has ceased recruiting participants as of November 21st 2023. It was initially posted to the site on December 1st 2023. Despite no longer being open for recruitment, there are 493 other medical studies that could still use volunteers at this time."

Answered by AI

What is the end goal of this controlled experiment?

"By studying participants over an approximate 18 week period, this trial aims to measure any changes in task strain from pre-intervention to post-intervention. Secondary objectives encompass evaluating fluctuations in clinic blood pressure, momentary positive affect and mean ambulatory blood pressure between baseline and the end of treatment."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Mindfulness App Training for Cardiovascular Health

Thomas Kamarck 2024. "Mindfulness App Training for Cardiovascular Health". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT06152185.

All > Paid Studies Pittsburgh