Oleocanthal-Rich Extra Virgin Olive Oil for Cardiovascular Disease

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Department of Nutrition, Davis, CACardiovascular Disease+2 MoreOleocanthal-Rich Extra Virgin Olive Oil - Other
Eligibility
20 - 45
Male
What conditions do you have?
Select

Study Summary

This trial will observe the effects of oleocanthal-rich olive oil on platelet function over a 6 hour period.

Eligible Conditions
  • Cardiovascular Disease
  • Platelet Aggregation
  • Nutritional and Metabolic Disorders

Treatment Effectiveness

Study Objectives

1 Primary · 4 Secondary · Reporting Duration: baseline, 2, 4 and 6 hours

Hour 6
Influence of Oleocanthal-rich EVOO intake on Adenosine Diphosphate-induced platelet aggregometry
Arachidonic acid
Influence of Oleocanthal-rich EVOO intake on Collagen-induced platelet aggregometry
Influence of Oleocanthal-rich EVOO intake on Metabolomics
Oxylipins

Trial Safety

Trial Design

2 Treatment Groups

Oleocanthal-Rich Extra Virgin Olive Oil
1 of 2
Oleocanthal-Low Extra Virgin Olive Oil
1 of 2

Experimental Treatment

Non-Treatment Group

50 Total Participants · 2 Treatment Groups

Primary Treatment: Oleocanthal-Rich Extra Virgin Olive Oil · Has Placebo Group · N/A

Oleocanthal-Rich Extra Virgin Olive OilExperimental Group · 2 Interventions: Oleocanthal-Rich Extra Virgin Olive Oil, Oleocanthal-low Extra Virgin Olive Oil · Intervention Types: Other, Other
Oleocanthal-Low Extra Virgin Olive OilPlaceboComparator Group · 2 Interventions: Oleocanthal-Rich Extra Virgin Olive Oil, Oleocanthal-low Extra Virgin Olive Oil · Intervention Types: Other, Other

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: baseline, 2, 4 and 6 hours

Who is running the clinical trial?

University of California, DavisLead Sponsor
853 Previous Clinical Trials
5,017,653 Total Patients Enrolled

Eligibility Criteria

Age 20 - 45 · Male Participants · 7 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
Your body mass index (BMI) falls between 18.5 and 30 kg/m2.
You are okay with drinking 2 tablespoons (40 mL) of olive oil.
You are between the ages of 20 and 45.
Women must have a menstrual cycle of 25-30 days.

Frequently Asked Questions

Is there any way for me to join the clinical research?

"This clinically-directed investigation is seeking out 50 individuals, aged 20 to 45 and diagnosed with cardiovascular diseases. Other criteria include: gender (M: Trials 1 & 2; M/F : Trial 3), a BMI between 18.5 - 30 kg/m2 and weight of no less than 110 pounds, as well as the capacity and willingness to adhere to trial protocols and ingest 40 mL of olive oil daily." - Anonymous Online Contributor

Unverified Answer

Is this research study open to individuals aged 25 or older?

"This clinical trial has a narrow age range of 20 to 45, whereas there are 55 trials accepting those under the legal age and 439 studies welcoming participants over 65." - Anonymous Online Contributor

Unverified Answer

Is there any availability for participants to join this experimentation?

"Affirmative. According to clinicaltrials.gov, the trial initially posted on April 2nd 2018 is still looking for volunteers. 50 patients are required from one facility with the most recent edit taking place June 2nd 2022." - Anonymous Online Contributor

Unverified Answer

What is the total enrollment of this research project?

"That is correct. According to information published on clinicaltrials.gov, this experiment was first posted in April 2018 and has been actively recruiting since June 2022. A total of 50 participants will be taken from a single medical centre for the trial." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.