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Phenolic Compound

Oleocanthal-Rich Olive Oil for Platelet Aggregation

N/A
Waitlist Available
Research Sponsored by University of California, Davis
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline, 2, 4 and 6 hours
Awards & highlights

Summary

This trial will observe the effects of oleocanthal-rich olive oil on platelet function over a 6 hour period.

Who is the study for?
This trial is for men and women aged 20-45, with a BMI of 18.5-30 kg/m2, who can follow the study plan. Men must weigh at least 110 pounds; women need regular menstrual cycles. Excluded are those with blood disorders, under medical supervision, on certain medications or diets, or with allergies to olives/oil.Check my eligibility
What is being tested?
The study tests how two types of extra virgin olive oil (one low in oleocanthal and one rich in it) affect platelet function when consumed with food over different times compared to fasting overnight.See study design
What are the potential side effects?
While not explicitly listed in the provided information, potential side effects may include digestive discomfort due to olive oil intake and possible changes in blood parameters related to platelet function.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline, 2, 4 and 6 hours
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline, 2, 4 and 6 hours for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Influence of Oleocanthal-rich EVOO intake on Collagen-induced platelet aggregometry
Secondary outcome measures
Influence of Oleocanthal-rich EVOO intake on Adenosine Diphosphate-induced platelet aggregometry
Arachidonic acid
Influence of Oleocanthal-rich EVOO intake on Metabolomics
+1 more

Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: Oleocanthal-Rich Extra Virgin Olive OilExperimental Treatment2 Interventions
Extra Virgin Olive Oil that is high in the phenolic oleocanthal, but contains similar amounts of total phenolics as the Oleocanthal-Low Extra Virgin Olive Oil
Group II: Oleocanthal-Low Extra Virgin Olive OilPlacebo Group2 Interventions
Extra Virgin Olive Oil that is low in the phenolic oleocanthal, but contains similar amounts of total phenolics as the Oleocanthal-Rich Extra Virgin Olive Oil

Find a Location

Who is running the clinical trial?

University of California, DavisLead Sponsor
919 Previous Clinical Trials
4,720,866 Total Patients Enrolled

Media Library

Oleocanthal (Phenolic Compound) Clinical Trial Eligibility Overview. Trial Name: NCT03528603 — N/A
Cardiovascular Disease Research Study Groups: Oleocanthal-Low Extra Virgin Olive Oil, Oleocanthal-Rich Extra Virgin Olive Oil
Cardiovascular Disease Clinical Trial 2023: Oleocanthal Highlights & Side Effects. Trial Name: NCT03528603 — N/A
Oleocanthal (Phenolic Compound) 2023 Treatment Timeline for Medical Study. Trial Name: NCT03528603 — N/A
~4 spots leftby Jul 2025