250 Participants Needed

CBT + Low FODMAP Diet for IBS

Recruiting at 1 trial location
RJ
CA
Overseen ByCynthia A. Boutte, BSN
Age: < 18
Sex: Any
Trial Phase: Academic
Sponsor: Baylor College of Medicine
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial aims to determine whether cognitive behavioral therapy (CBT) or a low FODMAP diet benefits children with irritable bowel syndrome (IBS) or functional abdominal pain more. Simple tests will identify which treatment might work best for each child. Children aged 7-12 who frequently experience stomach pain without an identifiable medical cause may be suitable candidates. Participants will either undergo CBT or follow the low FODMAP diet to assess which approach reduces their symptoms. As an unphased trial, this study offers a unique opportunity for participants to contribute to understanding effective treatments for children's abdominal pain.

Will I have to stop taking my current medications?

The trial information does not specify whether you need to stop taking your current medications. However, if you have been treated with antibiotics or probiotics in the last two months, you would not be eligible to participate.

Is there any evidence suggesting that this trial's treatments are likely to be safe?

Research shows that both Cognitive Behavioral Therapy (CBT) and the low FODMAP diet are generally safe and well-tolerated. CBT, a type of talk therapy, helps people change negative thinking patterns. It is widely used and has a strong safety record for various conditions, including irritable bowel syndrome (IBS).

For the low FODMAP diet, studies have shown it reduces symptoms in people with IBS. This diet involves consuming foods low in certain carbohydrates that can cause bloating and discomfort. Research indicates that following this diet for 12 weeks does not lead to major nutritional issues. It is also recommended as a first choice for managing IBS symptoms through diet.

Overall, extensive studies have deemed both treatments safe for people to try.12345

Why are researchers excited about this trial?

Researchers are excited about combining Cognitive Behavioral Therapy (CBT) with a low FODMAP diet for IBS because this approach tackles both the psychological and dietary aspects of the condition. While standard treatments often focus on medication to relieve symptoms, this combination offers a holistic strategy by addressing stress and anxiety through CBT and reducing digestive discomfort with a tailored diet. This dual approach could lead to improved symptom management and overall quality of life for IBS sufferers, setting it apart from traditional treatments that may only target one dimension of the condition.

What evidence suggests that this trial's treatments could be effective for IBS?

This trial will compare Cognitive Behavioral Therapy (CBT) with the Low FODMAP diet for managing Irritable Bowel Syndrome (IBS). Research has shown that CBT effectively reduces IBS symptoms, often leading to significant and lasting improvements. One study found that CBT outperformed usual care in easing IBS symptoms. Meanwhile, the Low FODMAP diet has proven effective for many with IBS, with up to 86% of patients reporting reduced abdominal pain and bloating. This diet involves avoiding certain foods that are difficult to digest and can cause discomfort. Both treatments have strong evidence supporting their effectiveness in managing IBS symptoms.678910

Who Is on the Research Team?

RJ

Robert J. Shulman, MD

Principal Investigator

Baylor College of Medicine

RL

Rona Levy, PhD

Principal Investigator

University of Washington

Are You a Good Fit for This Trial?

This trial is for children aged 7-12 with functional gastrointestinal disorders like IBS, who experience abdominal pain without an organic cause. They must understand English due to the nature of assessments and treatments involved. Kids with past bowel surgery, chronic diseases like Crohn's or diabetes, developmental disorders, or those already on FODMAP diets or CBT are excluded.

Inclusion Criteria

Parents and children must speak and understand English because of the psychological assessment and CBT requirements
My child is 7-12 years old with stomach pain not caused by a physical illness.

Exclusion Criteria

My child has had surgery on their intestines before.
Kids who cannot be chosen at random to follow the low FODMAP diet for some reason.
My child follows a vegetarian diet.
See 8 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Children are randomized to receive either Cognitive Behavioral Therapy or a low FODMAP diet for a 3-week treatment period

3 weeks

Follow-up

Participants are monitored for safety and effectiveness after treatment

6 months

What Are the Treatments Tested in This Trial?

Interventions

  • Cognitive Behavioral Therapy
  • Low FODMAP Diet
Trial Overview The study aims to determine if certain biomarkers can predict whether a child would benefit more from Cognitive Behavioral Therapy (CBT) or a Low FODMAP Diet for managing symptoms of pediatric chronic pain associated with gastrointestinal issues.
How Is the Trial Designed?
2Treatment groups
Experimental Treatment
Group I: Low FODMAP dietExperimental Treatment1 Intervention
Group II: Cognitive Behavioral TherapyExperimental Treatment1 Intervention

Cognitive Behavioral Therapy is already approved in European Union, United States, Canada for the following indications:

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Approved in European Union as Cognitive Behavioral Therapy for:
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Approved in United States as Cognitive Behavioral Therapy for:
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Approved in Canada as Cognitive Behavioral Therapy for:

Find a Clinic Near You

Who Is Running the Clinical Trial?

Baylor College of Medicine

Lead Sponsor

Trials
1,044
Recruited
6,031,000+

University of Washington

Collaborator

Trials
1,858
Recruited
2,023,000+

Citations

Improvement in Gastrointestinal Symptoms After Cognitive ...CBT improvement rates post treatment are among the highest in the IBS outcome literature when examined on an absolute level. To put these data in context, ...
Cognitive-behavioral therapy for patients with irritable bowel ...These studies consistently demonstrate CBT as an effective treatment for alleviating IBS symptoms and these gains are maintained for at least 1 ...
Cognitive behavioural therapy for irritable bowel syndromeACTIB results showed that, at 12 months, both forms of CBT for IBS were significantly more effective than treatment as usual at reducing IBS ...
Internet-Delivered Cognitive Behavioral Therapy in ...In a meta-analysis of 18 randomized controlled trials, CBT was found to be more effective in patients with IBS than in control groups consisting ...
Effect of Brain-Gut Behavioral Treatments on Abdominal ...Among trials recruiting only patients with refractory global IBS symptoms, group CBT was more efficacious than routine care for abdominal pain, but no other ...
Cognitive–behavioral therapy for management of mental ...Cognitive–behavioral therapy (CBT) helps individuals to eliminate avoidant and safety-seeking behaviors that prevent self-correction of faulty beliefs.
Behavioral Therapy - StatPearls - NCBI Bookshelf - NIHBehavioral therapy is a practical approach to modifying behavior using techniques such as reinforcement, enhanced communication, shaping, and modeling.
Cognitive behavioral therapyCognitive behavioral therapy (CBT) is a form of psychotherapy that aims to reduce symptoms of various mental health conditions, primarily depression, ...
Cognitive Behavioral Therapy: Techniques, Types, and UsesCognitive behavioral therapy (CBT) is a treatment approach that helps you recognize negative or unhelpful thought and behavior patterns.
Comparative Efficacy of Cognitive-behavioral Therapy and ...The results showed that mindfulness-based therapy was effective in reduction of clinical symptoms and increasing the life quality of the ...
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