This trial is testing whether papaverine, which targets mitochondrial metabolism, can decrease cancer growth when given with chemoradiation to patients with stage II-III non-small cell lung cancer.
- Non-Small Cell Lung Cancer
- Stage II Lung Cancer
- Stage III Lung Cancer
- Stage IIIB Lung Cancer
- Stage IIB Lung Cancer
- Stage IIA Lung Cancer
- Stage IIIA Lung Cancer
- Non-Small Cell Lung Carcinoma
1 Primary · 9 Secondary · Reporting Duration: At 12 and 24 months post-treatment
1 Treatment Group
Treatment (papaverine, RT, paclitaxel, carboplatin)
1 of 1
28 Total Participants · 1 Treatment Group
Primary Treatment: Papaverine · No Placebo Group · Phase 1
Who is running the clinical trial?
Age 18+ · All Participants · 24 Total Inclusion CriteriaMark “Yes” if the following statements are true for you:
Who else is applying?
What state do they live in?
How old are they?
|18 - 65||100.0%|
What site did they apply to?
|Ohio State University Comprehensive Cancer Center||100.0%|
What portion of applicants met pre-screening criteria?
Frequently Asked Questions
What kind of health risks might patients take when they use Papaverine?
"Papaverine's safety was evaluated to be a score of 1, since this is an inaugural trial and there is minimal evidence confirming its efficacy or security." - Anonymous Online Contributor
What is the highest amount of participants enrolled in this clinical experiment?
"Correct. Clinicaltrials.gov verifies that this medical research project, which was initially made public on December 6th 2021, is searching for suitable participants at present. The trial seeks 28 volunteers from a single site." - Anonymous Online Contributor
Is enrollment for this clinical research still open to participants?
"According to the clinicaltrials.gov listing, this medical trial is still recruiting participants - with an initial post date of December 6th 2021 and a most recent update on April 18th 2022." - Anonymous Online Contributor
Has Papaverine previously been studied in a medical setting?
"Currently, 1433 medical trials are being conducted on Papaverine. 365 of these research projects have reached the advanced phase 3 stage. Most of these studies occur in Shanghai; however, 74682 different sites worldwide are hosting clinical trials related to this drug." - Anonymous Online Contributor
In what medical cases has Papaverine been prescribed?
"Papaverine is commonly used to combat advanced soft tissue sarcoma, yet its effects can also be useful in addressing recurrent and advanced cervical cancer." - Anonymous Online Contributor