Handgrip Training for Vascular Health in Sedentary Lifestyle
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial tests whether squeezing a handgrip can improve blood vessel health in the brain for people who aren't very active. The handgrip exercise might lower blood pressure and boost overall vascular health. Participants will be divided into two groups: one will perform a stronger handgrip exercise, while the other will do a much lighter version for comparison. This trial suits individuals aged 18 to 35 who haven't been active recently and aren't dealing with serious health issues like heart or brain conditions. As an unphased trial, it offers a unique opportunity to contribute to research that could enhance brain health through simple exercises.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications.
What prior data suggests that isometric handgrip training is safe for improving vascular health?
Research shows that isometric handgrip training is generally safe. Studies have found that this exercise can significantly lower systolic blood pressure. Participants usually tolerate it well.
Other reports have used isometric handgrip training to assess health status and the risk of diseases like high blood pressure. No major negative effects have been linked to this exercise method, suggesting its safety.
Overall, evidence supports that isometric handgrip training safely improves heart and blood vessel health without serious side effects.12345Why are researchers excited about this trial?
Researchers are excited about handgrip training for vascular health in people with sedentary lifestyles because it offers a simple, non-invasive way to potentially improve cardiovascular health. Most treatments for vascular issues focus on medications and lifestyle changes like diet and exercise, which can be challenging to maintain. Handgrip training is unique because it targets vascular health directly through isometric exercises, which involve squeezing a handgrip at 30% of maximum strength to increase blood flow and potentially improve heart function. This method is easy to perform, doesn't require special equipment or a gym, and could be an accessible option for people who struggle with traditional exercise routines.
What evidence suggests that handgrip training is effective for improving brain blood vessel function?
Studies have shown that squeezing a handgrip can significantly lower resting blood pressure, reducing both systolic and diastolic numbers. Research also indicates it can lower resting heart rate and arterial pressure in individuals with normal blood pressure. For those with prehypertension, handgrip exercises effectively reduce blood pressure. These findings suggest that this exercise could improve vascular health, potentially benefiting blood vessels in the brain. In this trial, participants will undergo either an isometric handgrip training intervention at 30% of maximum grip strength or a sham comparator at 5% of maximum grip strength to evaluate effects on vascular health.16789
Are You a Good Fit for This Trial?
This trial is for adults who lead a sedentary lifestyle and are interested in participating in a study to improve brain blood vessel function. Specific eligibility criteria details were not provided, so participants should inquire about any additional requirements.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants undergo isometric handgrip training at 30% or 5% of maximum grip strength
Follow-up
Participants are monitored for changes in cerebrovascular function and blood pressure
What Are the Treatments Tested in This Trial?
Interventions
- Handgrip Training
Find a Clinic Near You
Who Is Running the Clinical Trial?
Florida State University
Lead Sponsor