Handheld Diagnostic Device for Neurological Disorders

SA
LP
Overseen ByLauren Perrey-Moore, BSN
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Indiana University
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial tests a new handheld device designed to help doctors quickly diagnose neurological disorders. The goal is to determine if this point-of-care electro-diagnostic device can provide real-time information to improve patient care and expedite treatment. Patients 18 and older receiving care at IU Health facilities, who can give consent or have a representative do so, are eligible to participate. The device will assess participants, and its data will be compared with standard clinical diagnostics. As an unphased trial, this study allows patients to contribute to innovative diagnostic advancements that could enhance future neurological care.

Do I need to stop my current medications for the trial?

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.

What prior data suggests that this handheld diagnostic device is safe for neurological disorders?

Research has shown that the handheld point-of-care (POC) electro-diagnostic device is generally considered safe. It uses technology from Texas Instruments and relies on a reliable electronic board. This setup offers a cost-effective method for collecting information about the nervous system.

Although specific data on side effects for this exact device is unavailable, similar devices have been used without major safety issues. These devices typically gather information from the body without requiring surgery, making them generally well-tolerated by patients.

The trial's phase is "Not Applicable," indicating that the study focuses more on data collection than on testing safety. The technology in this device comes from well-known and trusted sources, supporting its safe use.

For those considering joining a trial with this device, the risks are likely low. However, discussing any concerns with the trial team is always advisable.12345

Why are researchers excited about this trial?

Researchers are excited about the handheld point-of-care electro-diagnostic device because it offers a new way to diagnose neurological disorders quickly and efficiently. Unlike traditional diagnostic methods that often require complex equipment and lengthy testing in specialized facilities, this device is portable and can be used at the patient's location, potentially speeding up the diagnostic process. It aims to provide immediate, accurate data, allowing for faster treatment decisions and improving patient care. This innovation could revolutionize how neurological disorders are diagnosed, making the process more accessible and convenient.

What evidence suggests that this handheld diagnostic device is effective for neurological disorders?

Research has shown that handheld Point of Care (POC) devices can diagnose and treat brain and nerve conditions much faster. This speed is crucial because quicker treatment often leads to better health outcomes. In this trial, participants will undergo evaluation using a handheld POC electro-diagnostic device to compare its diagnostic data with clinical diagnostic data. One study found that POC-EEG devices, which monitor brain activity, were 97.4% accurate in identifying unusual brain patterns and 90.9% accurate in ruling them out. These devices were also 82.4% accurate in detecting Parkinson's Disease and 97.0% accurate in confirming its absence. This evidence suggests that these handheld devices can effectively diagnose and manage neurological conditions quickly.13678

Who Is on the Research Team?

SA

Sergiu Abramovici, MD

Principal Investigator

Indiana University

Are You a Good Fit for This Trial?

This trial is for adults over 18 with neurological impairments who are seen at IU Health facilities. They must be able to consent or have a representative who can. Excluded are those with skin lesions, implanted stimulators, lacking standard imaging comparisons, severe illnesses as judged by the PI, or pregnant women.

Inclusion Criteria

Seen inpatient or in outpatient service at IU Health facilities - Methodist Hospital, and the Neuroscience Center, by a Neurology and/or Neurosurgery consultant as part of their SOC
The participant has capacity to sign consent or has an assigned LAR (Legally Authorized Representative - Spouse, parent, sibling, etc.) able to consent on their behalf
I am 18 years old or older.

Exclusion Criteria

Pregnant woman
PI unblinded by participant or LAR regarding indication or clinical data
Implanted stimulation devices (any)
See 3 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants are evaluated using the handheld POC device to compare diagnostic data collected vs. clinical diagnostic data

2 years

Follow-up

Participants are monitored for safety and effectiveness after treatment

4-8 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • Handheld Point of Care Electro-Diagnostic Device
Trial Overview The study tests a handheld Point of Care (POC) electro-diagnostic device used by providers to gain immediate diagnostic insights for quicker treatment decisions in neurological conditions. It uses limited electrodes and stimulation modalities like SSEP, VEP, and BAEP.
How Is the Trial Designed?
1Treatment groups
Experimental Treatment
Group I: Treatment ArmExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Indiana University

Lead Sponsor

Trials
1,063
Recruited
1,182,000+

Citations

Handheld Point of Care Electro-Diagnostic DeviceThis can significantly shorten time to treatment which in several neurological and neurosurgical conditions, and thus, can significantly improve ...
Handheld Diagnostic Device for Neurological DisordersTrial Overview The study tests a handheld Point of Care (POC) electro-diagnostic device used by providers to gain immediate diagnostic insights ...
Could a hand-held, visual electrophysiology device ...Could a hand-held, visual electrophysiology device theoretically reduce diagnostic waiting times for complex eye conditions in the NHS?
Handheld Point of Care Electro-Diagnostic Device | MedPathThis can significantly shorten time to treatment which in several neurological and neurosurgical conditions, and thus, can significantly improve ...
Point-of-Care Electroencephalography in Acute ...POC-EEG demonstrated a sensitivity of 97.4% and specificity of 90.9% for abnormal patterns, with PD detection showing 82.4% sensitivity and 97.0% specificity ...
Handheld Point of Care Electro-Diagnostic DeviceThe POC investigational electrodiagnostic prototype was assembled using OpenBCI8 electronic board and electrodes, based on ADS 129X chip by ...
Wearable devices in neurological disorders - PubMed CentralThe data collected encompasses physiological, biochemical, and imaging information. Wearable devices are mainly utilized for health and safety ...
Automated Hand-Held Nerve Conduction DevicesThe use of automated hand-held nerve conduction devices is among the newest and most controversial topics in the field of electrodiagnostic (EDX) medicine.
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