Accuryn Foley Catheter Device for Atrial Tachycardia

(IAP Trial)

KR
Overseen ByKaruna Rajkumar, MD
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Wake Forest University Health Sciences
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial examines how the Accuryn Foley Catheter measures abdominal pressure during a heart procedure called pulsed field ablation. Researchers aim to determine how different types of anesthesia affect these pressure readings. The trial includes adults undergoing pulsed field ablation for irregular heartbeat conditions such as atrial fibrillation or atrial flutter, who can have a Foley catheter placed without complications. Participants should not have had recent abdominal surgery or certain urinary conditions. As an unphased trial, participants contribute to innovative research that could enhance future heart procedures.

Do I need to stop my current medications for this trial?

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.

What prior data suggests that the Accuryn Foley Catheter Device is safe for measuring intra-abdominal pressure?

Research has shown that the Accuryn Foley Catheter Device, which measures abdominal pressure, is generally well-tolerated. Collecting continuous, real-time data on abdominal pressure and urine output has been safely conducted in similar situations, suggesting the device's safety. Although specific data on side effects for this exact use is lacking, Foley catheters are commonly used in healthcare, supporting their safety. Prospective participants should discuss any concerns with their doctor.12345

Why are researchers excited about this trial?

Researchers are excited about the Accuryn Foley Catheter Device for atrial tachycardia because it introduces a novel approach by measuring intra-abdominal pressure. Unlike standard treatments for atrial tachycardia, which usually involve medications or ablation procedures to regulate heart rhythm, this device offers a potential non-invasive way to monitor and potentially influence heart health through pressure measurement. This innovative method could provide real-time data, helping to manage the condition more effectively and with potentially fewer side effects than traditional treatments.

What evidence suggests that the Accuryn Foley Catheter Device is effective for measuring intra-abdominal pressure during atrial tachycardia procedures?

Research has shown that the Accuryn Foley Catheter Device can continuously measure abdominal pressure and track urine output in real time. This real-time monitoring may enhance safety during medical procedures, such as pulsed field ablation, used to treat atrial tachycardia. Studies suggest that accurately tracking urine can help detect kidney problems early and improve patient health. The Accuryn system automates these measurements, potentially providing more reliable data than traditional methods. Although it is still under study for atrial tachycardia in this trial, its innovative monitoring approach holds promise for improving patient care.12346

Who Is on the Research Team?

KR

Karuna Rajkumar, MD

Principal Investigator

Wake Forest University Health Sciences

Are You a Good Fit for This Trial?

This trial is for patients with atrial tachycardia or abdominal compartment syndrome. Specific eligibility criteria are not provided, so it's important to contact the study team for details on who can participate.

Inclusion Criteria

I am an adult getting pulse field ablation for atrial fibrillation/flutter.
I can safely have a Foley catheter and pressure monitoring inside my abdomen.

Exclusion Criteria

Pregnant or breastfeeding individuals
I have not had surgery in my belly area in the last 6 months.
I do not have issues with bladder procedures or a history of prostate problems.
See 1 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants undergo Pulsed Field Ablation (PFA) with intra-abdominal pressure monitoring using the Accuryn system

1 day
1 visit (in-person)

Follow-up

Participants are monitored for safety and effectiveness after the procedure, including tracking of urinary tract infections and unplanned hospital admissions

1 week
1 visit (in-person)

What Are the Treatments Tested in This Trial?

Interventions

  • Accuryn Foley Catheter Device
Trial Overview The study is testing how intra-abdominal pressure changes using the Accuryn Foley catheter device during pulsed field ablation procedures for heart rhythm disorders, and comparing this with different types of anesthesia used.
How Is the Trial Designed?
1Treatment groups
Experimental Treatment
Group I: Accuryn Foley catheter placementExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Wake Forest University Health Sciences

Lead Sponsor

Trials
1,432
Recruited
2,506,000+

Citations

Accuryn Foley Catheter Device for Atrial Tachycardia (IAP ...The purpose of this study is to investigate the intra-abdominal pressure utilizing the Accuryn monitoring system during pulsed field ablation procedures in ...
Intra-abdominal Pressure (IAP) During PFA Treatment of A ...The Accuryn monitor allows for continuous, real-time measurement of IAP and urine output, providing data that may enhance procedural safety and provide insights ...
Intra-abdominal hypertension in cardiac surgery patientsData collected included high-resolution urine output, intra-abdominal pressure, and core body temperature. The Accuryn Monitoring System ...
Accuryn Clinical Evidence SummaryIntensive monitoring of urine output is associated with increased detection of acute kidney injury and improved outcomes. Traditional Foley drainage systems—Do ...
The Memo: Accuryn Medical Bringing Innovation to Urine ...The Accuryn Monitoring System is the first of its kind, providing real-time, automated urine output (UO) measurement, intra-abdominal pressure ( ...
Automated Intra-abdominal Pressure Monitoring During ...Ultimately, automated IAP monitoring, early detection of ACS, and subsequent treatment of ACS improved clinical outcomes for this patient.
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