150 Participants Needed

Eye Complications for Cancer Therapy

SS
Overseen BySarah Sunshine, MD
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: University of Maryland, Baltimore
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

Trial Summary

What is the purpose of this trial?

The purpose of this study is to collect data on patients seen at University of Maryland after undergoing cancer therapy. Previous medications, ocular history, medical history, clinical evaluations, surgical procedures and outcomes will be gathered on the patients who consent to participate. Potential subjects will be enrolled from the clinical practice of the investigator at the time of their eye examination visit. A standard of care exam will be performed pertinent to the reason for the visit. In addition to the standard of care exam, certain biological specimens (ocular surface wash, mucocellular material, corneal filaments, impression cytology, and/or blood) will be collected, stored, and analyzed to obtain immunologic, cellular, or molecular mechanistic insights into disease pathogenesis.

Eligibility Criteria

This trial is for adults over 18 who've had a stem cell transplant or cancer therapy and are seeing an eye doctor at the University of Maryland. They shouldn't have a history of serious eye diseases, except mild dry eye or past surgeries like cataract removal.

Inclusion Criteria

I am over 18 years old.
I can understand and have signed the consent form.
I don't have eye diseases, except for possibly cataracts, glaucoma, mild dry eye, or past eye surgeries.
See 4 more

Timeline

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Intervention

Participants undergo an eye exam and research protocols such as tear collection, impression cytology, and blood collection

1 visit
1 visit (in-person)

Follow-up

Participants are monitored for ocular complications and outcomes post-cancer therapy

3 months to 10 years

Treatment Details

Interventions

  • Eye exam
Trial Overview The study collects health data during standard eye exams from patients treated for cancer to understand ocular complications better. It also involves collecting and analyzing biological samples to gain insights into disease mechanisms.
Participant Groups
2Treatment groups
Experimental Treatment
Active Control
Group I: Cancer TherapyExperimental Treatment1 Intervention
The intervention administered will be the eye exam and research protocols (e.g. tear collection, impression cytology, and blood collection)
Group II: ControlActive Control1 Intervention
The intervention administered will be the standard of care procedures of the eye exam.

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of Maryland, Baltimore

Lead Sponsor

Trials
729
Recruited
540,000+
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top
Terms of Service·Privacy Policy·Cookies·Security