Glaucoma Screening for Glaucoma
(G-SEARCH Trial)
Trial Summary
What is the purpose of this trial?
The vast majority of glaucoma cases in the United States go undetected and untreated until the late stages of the disease. Open-angle glaucoma is a progressive condition that is asymptomatic in its early to moderate stages and may be amenable to screening through telemedicine-based approaches. This study is a randomized trial to evaluate whether glaucoma screening with established tests (e.g., optical coherence tomography, fundus photography, and tonometry) is more effective for detecting undiagnosed glaucoma cases compared to education alone or delayed intervention.
Do I need to stop my current medications for this trial?
The trial information does not specify whether you need to stop taking your current medications.
What data supports the effectiveness of the treatment Glaucoma Screening with Optical Coherence Tomography (OCT), Color Fundus Photography, and Tonometry?
Research shows that optical coherence tomography (OCT) is effective in screening for glaucoma, especially in high-risk groups, and can help detect early signs of the disease. Additionally, combining OCT with fundus photography improves diagnostic accuracy, making it a useful tool for glaucoma screening.12345
Is glaucoma screening using OCT, color fundus photography, and tonometry safe for humans?
The research articles focus on the effectiveness and diagnostic capabilities of optical coherence tomography (OCT) for glaucoma screening, but they do not provide specific safety data. Generally, OCT, color fundus photography, and tonometry are non-invasive and widely used in eye exams, suggesting they are considered safe for human use.13678
How is the glaucoma screening treatment with OCT, color fundus photography, and tonometry different from other treatments?
This treatment is unique because it uses a combination of optical coherence tomography (OCT), which provides detailed images of the eye's structures, color fundus photography to capture images of the retina, and tonometry to measure eye pressure, making it a comprehensive approach for early detection and monitoring of glaucoma.135910
Research Team
Jeremy D Keenan, MD, MPH
Principal Investigator
University of California, San Francisco
Yvonne Ou, MD
Principal Investigator
University of California, San Francisco
Eligibility Criteria
This trial is for Californians at risk of glaucoma who haven't been diagnosed yet. It's not clear what specific inclusion or exclusion criteria are, but typically participants would need to meet certain age and health requirements.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants undergo telemedicine-based glaucoma screening using optical coherence tomography, fundus photography, and tonometry
Follow-up
Participants are monitored for outcomes such as cataract surgery, eyeglasses purchase, and quality of life over a 12-month period
Treatment Details
Interventions
- Glaucoma Screening with Optical Coherence Tomography (OCT), Color Fundus Photography, and Tonometry
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of California, San Francisco
Lead Sponsor
Centers for Disease Control and Prevention
Collaborator