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Behavioural Intervention

Virtual Reality Rehabilitation for Hemianopia in Children (HH-IVR Trial)

Waitlist Available
Research Sponsored by The Hospital for Sick Children
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Age > 8 years old
Be younger than 65 years old
Must not have
History of vertigo or dizziness
Prior vision rehabilitation interventions
Screening 3 weeks
Treatment Varies
Follow Up 7 months
Awards & highlights


This trial seeks to investigate the use of a home-based stimulation visual rehabilitation program using immerse-virtual reality in children aged 4-10 years old with a diagnosis of hemianopia.

Who is the study for?
This trial is for children aged over 8 with hemianopia, a type of visual field loss, due to a brain tumor or its treatment. They must have decent vision (BCVA > 20/200), be able to follow instructions, and have home Wi-Fi. Kids with vertigo, previous vision rehab, certain eye diseases or drug use can't join.Check my eligibility
What is being tested?
The study tests a home-based visual rehabilitation program using immersive virtual reality (IVR) designed for kids with hemianopia. It aims to see if this technology helps improve their ability to see and interact with the world around them.See study design
What are the potential side effects?
Potential side effects may include discomfort from wearing VR equipment, eye strain from prolonged screen time, and possibly dizziness or disorientation related to VR use.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
You are older than 8 years.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:
You have a history of feeling dizzy or lightheaded.
You have had previous treatments to improve your vision.


Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~7 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and 7 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Feasibility and effectiveness of a home based audiovisual stimuaton in immersive virtual-reality to restore visual perception in children with brain tumour associated hemianopia.
Secondary outcome measures
Change in Field of vision
Change in Quality of life
Change in Reading speed
+1 more

Trial Design

1Treatment groups
Experimental Treatment
Group I: InterventionalExperimental Treatment1 Intervention
Immersive virtual-reality stimulation (IVR): 1 session of 3 blocks of 15 trials of 20 seconds each. Rest time is 1-2 minute(s) between blocks. 1 session lasts 19 minutes.1 session every 2 days for 4 weeks (15 sessions total).
First Studied
Drug Approval Stage
How many patients have taken this drug
Immersive Virtual-Reality Stimulation

Research Highlights

Information in this section is not a recommendation. We encourage patients to speak with their healthcare team when evaluating any treatment decision.
Mechanism Of Action
Side Effect Profile
Prior Approvals
Other Research
The most common treatments for Hemianopia, particularly those similar to Immerse-Virtual Reality (IVR) stimulation, work by stimulating visual pathways to promote neuroplasticity. IVR involves repetitive visual exercises that encourage the brain to adapt and reorganize itself, potentially restoring some visual field function. This approach is crucial for Hemianopia patients as it leverages the brain's ability to rewire itself, thereby improving visual function and enhancing the patient's quality of life.
Virtual Reality Game Playing in Amblyopia Therapy: A Randomized Clinical Trial.Low vision rehabilitation for better quality of life in visually impaired adults.Personality and stress influence vision restoration and recovery in glaucoma and optic neuropathy following alternating current stimulation: implications for personalized neuromodulation and rehabilitation.

Find a Location

Who is running the clinical trial?

The Hospital for Sick ChildrenLead Sponsor
692 Previous Clinical Trials
6,946,733 Total Patients Enrolled
University Health Network, TorontoOTHER
1,492 Previous Clinical Trials
490,034 Total Patients Enrolled

Media Library

Immersive Virtual-Reality Stimulation (Behavioural Intervention) Clinical Trial Eligibility Overview. Trial Name: NCT05065268 — N/A
Hemianopia Research Study Groups: Interventional
Immersive Virtual-Reality Stimulation (Behavioural Intervention) 2023 Treatment Timeline for Medical Study. Trial Name: NCT05065268 — N/A
Hemianopia Clinical Trial 2023: Immersive Virtual-Reality Stimulation Highlights & Side Effects. Trial Name: NCT05065268 — N/A
~3 spots leftby Jul 2025