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Proton Beam Therapy

Treatment for Head and Neck Cancers

N/A

Recruiting

Led By Samantha Hedrick, PhD, DABR

Research Sponsored by Thompson Cancer Survival Center

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Patient must have biopsy-proven squamous cell carcinoma, originating in the oral cavity, larynx, oropharynx, nasopharynx, or hypopharynx

Patients must be ≥ 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up comparisons to be conducted over a 5 year period

Awards & highlights

Study Summary

This trial aims to investigate skin reactions that happen during a type of radiation therapy called pencil beam scanning proton therapy. The researchers will test a technique called "Spot Delete" to see if it can help reduce

Who is the study for?

This trial is for individuals with various types of head and neck cancers, including oral squamous cell carcinoma. Participants must be suitable candidates for pencil beam scanning (PBS) proton therapy.Check my eligibility

What is being tested?

The study tests a 'Spot Delete' technique during PBS proton therapy to see if it reduces skin reactions in patients with head & neck cancer. It also examines how the energy transfer from protons affects these reactions.See study design

What are the potential side effects?

Potential side effects may include varying degrees of radiation dermatitis, which is a skin reaction that can cause redness, irritation, peeling or blistering in areas receiving treatment.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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My cancer is a type of squamous cell carcinoma located in my mouth, throat, or related areas.

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I am 18 years old or older.

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My breast cancer is in an early or locally advanced stage without spread to distant organs.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ comparisons to be conducted over a 5 year period

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~comparisons to be conducted over a 5 year period

This trial's timeline: 3 weeks for screening, Varies for treatment, and comparisons to be conducted over a 5 year period for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

"Spot Delete: Technique in Proton Therapy Reduces Radiation Dermatitis in Head and Neck Cancer Patients.

Secondary outcome measures

To investigate how the linear energy transfer (LET) of the proton beam is related to skin reactions.

0 / 3Eligibility criteria met

Find a Location

Who is running the clinical trial?

Thompson Cancer Survival CenterLead Sponsor

3 Previous Clinical Trials

700 Total Patients Enrolled

Samantha Hedrick, PhD, DABRPrincipal InvestigatorThompson Proton Center, Director of Medical Physics

1 Previous Clinical Trials

500 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is the total number of participants being recruited for this research investigation?

"Indeed, clinicaltrials.gov indicates that this trial is presently seeking participants. The initial posting of the study occurred on December 13th, 2023 and it was most recently updated on the same day. The aim is to recruit a total of 100 patients from a single site."

Answered by AI

Is the enrollment process currently open for this research study?

"Indeed, the information available on clinicaltrials.gov indicates that this particular trial is actively seeking individuals to participate. The initial posting of the study was on December 13th, 2023 and it has been recently updated as well on the same date. To complete the trial successfully, a total of 100 participants are needed from one designated site."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Evaluation of Radiobiological Effects in Skin Toxicities Head and Neck Cancer Patients With PBS Proton Therapy

2023. "Evaluation of Radiobiological Effects in Skin Toxicities Head and Neck Cancer Patients With PBS Proton Therapy". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT06183268.

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