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Fecal Microbiota Transplant for Clostridium Difficile and IBD
Study Summary
This trial will study the safety and effectiveness of Fecal Microbiota Transplants (FMT) in children with recurrent C. Difficile infections, with or without Inflammatory Bowel Disease (IBD). 454 pyrosequencing will be used to study the gut microbiota before and after transplantation.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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Who is running the clinical trial?
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- I am taking high doses of steroids.I have been diagnosed with Inflammatory Bowel Disease through tests.I have had C. difficile infection more than once or it is severe.I am between 3 and 21 years old.I am under 3 years old.I have another infection in my intestines.I am not pregnant and will take a pregnancy test if required.I have severe inflammatory bowel disease.I am currently taking or will take antibiotics for reasons other than C. diff infection.I have had side effects from a previous fecal transplant.I am at least 3 years old.
- Group 1: C. Difficile without IBD
- Group 2: C. Difficile with IBD
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Is there an opportunity for volunteers to join this research effort?
"This clinical trial, which was initially listed on December 1st 2015 and last updated on April 4th 2022, is not currently seeking applicants. Although this specific study is closed for recruitment, there are 500 other trials actively pursuing participants at the present moment."
Are there any eligibility criteria I must satisfy in order to participate in this experimental research?
"This latest clinical trial is seeking 250 participants aged between 3 and 21 with inflammatory bowel diseases (IBD). To be considered, entrants must match the following criteria: age of at least three years old; recurrent or moderate to severe C. difficile infection; approval from a study team member after completing a medical interview and physical examination; ages ranging inclusively from 3 to 21 years old."
Can patients younger than 55 years partake in this trial?
"This research looks to recruit participants aged between 3 and 21. There are 121 studies involving individuals under 18, while those aged over 65 have 390 distinct trials available to them."
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