C134 Re-Administration for Brain Tumors
Trial Summary
What is the purpose of this trial?
The purpose of this study is to determine how safe and how well-tolerated the experimental study drug, C134 is when re-administered into the brain where the tumor is located.
Do I need to stop taking my current medications for the trial?
The trial protocol does not specify if you need to stop taking your current medications, but you cannot be on any drugs active against HSV (a type of virus) or other investigational therapeutic agents. If you are on steroids, your dose should not increase within 2 weeks of the C134 administration.
What data supports the effectiveness of the treatment C134 for brain tumors?
How is the treatment C134 unique for brain tumors?
Research Team
James Markert, MD
Principal Investigator
The University of Alabama at Birmingham
Eligibility Criteria
This trial is for individuals with recurrent glioblastoma or similar brain tumors. Participants should have a tumor that has returned after previous treatment and be in good enough health to receive the experimental therapy directly into their brain.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive re-administration of C134 intratumorally to assess safety and tolerability
Follow-up
Participants are monitored for safety and effectiveness after treatment
Treatment Details
Interventions
- C134
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Alabama at Birmingham
Lead Sponsor