216 Participants Needed

Registry for Pediatric Gastroparesis

(PGpR2 Trial)

Recruiting at 5 trial locations
LM
PA
Overseen ByPeggy Adamo
Age: < 65
Sex: Any
Trial Phase: Academic
Sponsor: Johns Hopkins Bloomberg School of Public Health
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial aims to create a national registry of young people with gastroparesis, a condition where the stomach doesn't empty properly, and those with similar symptoms but normal gastric emptying. Researchers seek to better understand these conditions by tracking symptoms such as nausea, vomiting, and stomach pain over time. Children, teens, and young adults who have experienced these symptoms for at least 12 weeks and have undergone a gastric emptying study in the past year may be eligible to participate. As an unphased trial, this study offers participants the chance to contribute to valuable research that could enhance understanding and treatment of gastroparesis in young people.

Why are researchers excited about this trial?

Researchers are excited about the GpCRC Pediatric Gastroparesis Registry 2 because it's focusing on better understanding gastroparesis in children, a condition where the stomach can't empty food properly. Unlike typical treatments that often involve dietary changes, medications like antiemetics, or even surgical interventions, this registry aims to gather comprehensive data on the condition itself. By analyzing this data, researchers hope to identify patterns and factors that could lead to more effective and tailored treatments in the future. This approach has the potential to revolutionize how gastroparesis is managed in young patients by paving the way for innovations beyond current options.

Who Is on the Research Team?

GP

Geoffrey Preidis, MD, PhD

Principal Investigator

Baylor College of Medicine

DS

David Shade, JD

Principal Investigator

Johns Hopkins Bloomberg School of Public Health

Are You a Good Fit for This Trial?

Inclusion Criteria

You experience nausea, vomiting, early satiety and postprandial fullness; these symptoms may be accompanied by upper abdominal pain.
You have normal gastric emptying but experience symptoms of Gastroparesis or have already been part of the Pediatric Gastroparesis Registry study.
You must provide a signed and dated informed consent form as well as your assent, if applicable.
See 4 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Observation

Participants are observed for the natural history and clinical course of gastroparesis symptoms

48 weeks
Regular assessments at baseline and 48 weeks

Follow-up

Participants are monitored for changes in symptom severity and other clinical measures

4 weeks

What Are the Treatments Tested in This Trial?

Find a Clinic Near You

Who Is Running the Clinical Trial?

Johns Hopkins Bloomberg School of Public Health

Lead Sponsor

Trials
441
Recruited
2,157,000+

Children's Wisconsin

Collaborator

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3
Recruited
500+

Boston Children's Hospital

Collaborator

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801
Recruited
5,584,000+

Nationwide Children's Hospital

Collaborator

Trials
354
Recruited
5,228,000+

Baylor College of Medicine

Collaborator

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1,044
Recruited
6,031,000+

Massachusetts General Hospital

Collaborator

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3,066
Recruited
13,430,000+

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Collaborator

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2,513
Recruited
4,366,000+

Medical College of Wisconsin

Collaborator

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645
Recruited
1,180,000+

Texas Tech University Health Sciences Center, El Paso

Collaborator

Trials
51
Recruited
5,800+