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Regional Anesthesia

Nerve Block for Rib Fractures

N/A

Recruiting

Led By Daniel Kreider, MD

Research Sponsored by WellSpan Health

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up from date of randomization until the date of discharge from the hospital or death from any cause, whichever came first, assessed up to 100 months

Awards & highlights

Study Summary

This trial studies the effect of a nerve block to reduce pain in patients with multiple rib fractures, compared to using pain relief medicines alone.

Who is the study for?

This trial is for adults over 18 with one or more rib fractures confirmed by X-ray or CT scan, who visit WellSpan York Hospital's ED and need IV painkillers or oral opioids. It excludes those under 18, unable to consent, allergic to local anesthesia, needing urgent surgery, discharged immediately, revisiting for the same injury, or with other major injuries.Check my eligibility

What is being tested?

The study compares a pain relief technique called Serratus Anterior Plane Block (SAPB) guided by ultrasound against standard pain medications in patients with multiple rib fractures. The focus is on pain management effectiveness and overall patient outcomes like medication use and hospital stay length.See study design

What are the potential side effects?

While not explicitly listed here, side effects of SAPB may include discomfort at injection site, infection risk from needle insertion and potential nerve damage. Standard analgesics can cause drowsiness, constipation, nausea and increased risk of dependency.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ from date of randomization until the date of discharge from the hospital or death from any cause, whichever came first, assessed up to 100 months

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~from date of randomization until the date of discharge from the hospital or death from any cause, whichever came first, assessed up to 100 months

This trial's timeline: 3 weeks for screening, Varies for treatment, and from date of randomization until the date of discharge from the hospital or death from any cause, whichever came first, assessed up to 100 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Visual Analog Pain Score (VAS) at 2 hours

Secondary outcome measures

Length of Stay (hours)

Morphine Milligrams Equivalent (MME)

Pain Score

+3 more

Other outcome measures

Safety Outcomes

Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: Serratus Anterior Plane BlockExperimental Treatment2 Interventions

Subjects will undergo serratus anterior plane block, in addition to standard of care analgesic medications at the discretion of the treatment team.

Group II: Standard Analgesic MedicationsActive Control1 Intervention

Subjects will receive standard of care analgesic medications at the discretion of the treatment team.

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

WellSpan HealthLead Sponsor

28 Previous Clinical Trials

2,004,578 Total Patients Enrolled

Daniel Kreider, MDPrincipal InvestigatorWellSpan Health

Media Library

Serratus Anterior Plane Block (SAPB) (Regional Anesthesia) Clinical Trial Eligibility Overview. Trial Name: NCT05748366 — N/A

Multiple Rib Fractures Research Study Groups: Serratus Anterior Plane Block, Standard Analgesic Medications

Multiple Rib Fractures Clinical Trial 2023: Serratus Anterior Plane Block (SAPB) Highlights & Side Effects. Trial Name: NCT05748366 — N/A

Serratus Anterior Plane Block (SAPB) (Regional Anesthesia) 2023 Treatment Timeline for Medical Study. Trial Name: NCT05748366 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

How many individuals can potentially sign up for this clinical research?

"That is correct. The information accessible on clinicaltrials.gov suggests that the trial, first uploaded on March 31st 2023, is still actively recruiting participants from a single medical facility with an expected enrollment of 60 patients."

Answered by AI

Is recruitment for the study still open to participants?

"Indeed, the online registry clinicaltrials.gov shows that enrollment for this experiment is ongoing. It was first published on March 31st 2023 and recently updated on July 3rd 2023, targeting 60 volunteers from a single site."

Answered by AI

Recent research and studies

AnaesthesiaJournal

Serratus Plane Block: A Novel Ultrasound-guided Thoracic Wall Nerve Block

Blanco, R., T. Parras, J. G. McDonnell, and A. Prats-Galino. 2013. “Serratus Plane Block: A Novel Ultrasound-guided Thoracic Wall Nerve Block”. Anaesthesia. Wiley. doi:10.1111/anae.12344.

clinicaltrials.govStudy

Ultrasound Guided Serratus Anterior Plane Block for Rib Fractures

Daniel Kreider 2023. "Ultrasound Guided Serratus Anterior Plane Block for Rib Fractures". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05748366.