Light Therapy for Musculoskeletal Pain
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial explores how different colored lights might relieve pain by shining them into the eyes. Researchers aim to observe the brain's reaction to these lights, particularly in individuals with chronic muscle and joint pain. Participants will experience various light sequences to determine which might be most effective. The trial suits those who have experienced widespread pain for at least three months and do not plan to change their pain treatments soon. As an unphased trial, it offers a unique opportunity to contribute to innovative pain relief research without the constraints of traditional clinical trial phases.
Will I have to stop taking my current medications?
The trial does not specify if you need to stop your current medications, but you should not have any plans to change your medication or treatment in the next 3 months.
What prior data suggests that light therapy is safe for musculoskeletal pain?
Research has shown that light therapy is generally safe and easy to tolerate for pain relief. Studies have found that low-level light therapy, a type of light treatment, can significantly reduce pain with few side effects. This makes it a non-invasive and drug-free way to manage pain. One study indicated that this therapy can also improve bones, muscles, and cartilage, highlighting its broader benefits. Overall, light therapy is a safe method to relieve pain without major negative effects.12345
Why are researchers excited about this trial?
Researchers are excited about light therapy for musculoskeletal pain because it offers a non-invasive alternative to traditional treatments like NSAIDs, opioids, and physical therapy. Unlike these options, light therapy uses specific sequences of light, such as S-cone modulating or Static Green light, to potentially reduce pain and inflammation by influencing cellular activity. This innovative approach targets pain through light modulation, which could mean fewer side effects and a more natural healing process. If successful, it could provide faster relief and improve quality of life for those suffering from chronic pain.
What evidence suggests that light therapy could be an effective treatment for musculoskeletal pain?
Research has shown that light therapy can reduce pain for individuals with muscle and joint issues. Studies have found it lowers pain levels and improves mobility. Some research even suggests it outperforms ibuprofen for pain relief in the first 24 hours. Light therapy has also been associated with reduced fatigue and improved quality of life. In this trial, participants will join different experimental arms, each testing a unique light sequence. Overall, evidence suggests that light therapy might effectively manage muscle and joint pain.16789
Who Is on the Research Team?
Matthew Mauck, MD, PhD
Principal Investigator
University of North Carolina, Chapel Hill
Are You a Good Fit for This Trial?
This trial is for individuals with chronic musculoskeletal pain, such as fibromyalgia, and also includes a group of healthy participants. To join, people must meet specific criteria that will be assessed by the study team.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Pre-Scan Assessment
Participants undergo comprehensive assessment of covariates, quantitative sensory testing, and pressure pain threshold measurement
Scanning Session
Participants undergo MRI scanning to evaluate functional connectivity and brain activation patterns under different light stimuli
Follow-up
Participants are monitored for safety and effectiveness after the scanning session
What Are the Treatments Tested in This Trial?
Interventions
- Light Therapy
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of North Carolina, Chapel Hill
Lead Sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
Collaborator