Non-Invasive Vibration Therapy for Parkinson's Disease
Trial Summary
Will I have to stop taking my current medications?
The trial requires that you feel comfortable going off Parkinson's disease-related medication during in-person study visits and any medication that affects brain function or alters EEG activity before EEG recording. If you are taking a medication that may cause significant withdrawal effects, you may not be eligible to participate.
What data supports the effectiveness of the treatment Vibrotactile Coordinated Reset for Parkinson's Disease?
Research shows that vibration therapy, including Vibrotactile Coordinated Reset, can improve motor symptoms like tremor and rigidity in Parkinson's patients. Studies have demonstrated that these therapies can lead to better motor control and functional outcomes, suggesting they may be a promising non-drug treatment option.12345
Is non-invasive vibration therapy safe for humans?
How does the treatment Vibrotactile Coordinated Reset differ from other treatments for Parkinson's disease?
Vibrotactile Coordinated Reset (vCR) is unique because it is a non-invasive therapy that uses gentle vibrations on the fingertips to disrupt abnormal brain rhythms, aiming to improve motor symptoms in Parkinson's disease. Unlike traditional treatments that often involve medication or invasive procedures, vCR focuses on desynchronizing neural networks to provide long-lasting relief from symptoms.12578
What is the purpose of this trial?
The purpose of our study is to evaluate Vibrotactile Coordinated Reset stimulation (vCR) and its effects on advanced stage Parkinson's symptoms. VCR will be administered with a device called the Stanford CR Glove. vCR is expected to provide patients with a non-invasive alternative to the most widely used treatments such as levodopa and or deep brain stimulation. Patients will be followed for two years.
Eligibility Criteria
This trial is for people aged 35-90 with advanced Parkinson's Disease (stages 2 to 4), who are comfortable with technology and can manage without certain brain function medications during EEG recordings. They must not be pregnant, involved in other trials recently, have a history of significant brain surgery or severe psychiatric issues, or substance abuse problems.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive Vibrotactile Coordinated Reset stimulation using the Stanford CR Glove
Follow-up
Participants are monitored for safety and effectiveness after treatment
Treatment Details
Interventions
- Vibrotactile Coordinated Reset
Find a Clinic Near You
Who Is Running the Clinical Trial?
Stanford University
Lead Sponsor