← Back to Search

Genetic Testing

Genetic Counseling for Endometrial Cancer (OPTEC Trial)

N/A

Waitlist Available

Led By Paul Goodfellow

Research Sponsored by Ohio State University Comprehensive Cancer Center

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up up to 3 years

Awards & highlights

OPTEC Trial Summary

This trial will test if universal screening for DNA mismatch repair deficiency can help guide treatment strategies for endometrial cancer patients.

Eligible Conditions

Endometrial Cancer
Endometrial Adenocarcinoma
Lynch Syndrome
Family

OPTEC Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ up to 3 years

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~up to 3 years

This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 3 years for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Incidence of endometrial cancer patients with Lynch syndrome

Incidence of tumors with microsatellite instability and/or somatic POLE mutations

OPTEC Trial Design

1Treatment groups

Experimental Treatment

Group I: Comprehensive LS genetic testingExperimental Treatment4 Interventions

Testing for inherited forms of cancer and tumor sequencing

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

National Cancer Institute (NCI)NIH

13,663 Previous Clinical Trials

40,924,903 Total Patients Enrolled

75 Trials studying Endometrial Cancer

73,374 Patients Enrolled for Endometrial Cancer

Ohio State University Comprehensive Cancer CenterLead Sponsor

320 Previous Clinical Trials

289,165 Total Patients Enrolled

2 Trials studying Endometrial Cancer

346 Patients Enrolled for Endometrial Cancer

Paul GoodfellowPrincipal InvestigatorOhio State University Comprehensive Cancer Center

1 Previous Clinical Trials

3,600 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Does this investigation currently accept new participants?

"Clinicaltrials.gov reveals that this medical trial, which was first shared on March 30th 2018 and last updated on December 2nd 2022, is no longer actively recruiting patients. However, there are still 1,697 other clinical trials accepting participants at the present moment."

Answered by AI

Are there multiple locations within the state where this experiment is being conducted?

"9 medical centres are taking part in the recruitment process, including Aultman Health Foundation (Canton, Ohio), Ohio Health (Columbus) and TriHealth Cancer Institute-Westside (Cincinnati). Other sites that have joined this trial can be found throughout the nation."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Universal Endometrial Cancer DNA Sequencing for Detection of Lynch Syndrome and Personalized Care

Paul Goodfellow 2018. "Universal Endometrial Cancer DNA Sequencing for Detection of Lynch Syndrome and Personalized Care". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03460483.