taVNS for Dyslexia
Trial Summary
Will I have to stop taking my current medications?
The trial does not specify if you need to stop taking your current medications, but it does allow medications prescribed for ADHD.
How does the taVNS treatment for dyslexia differ from other treatments?
taVNS (transcutaneous auricular vagus nerve stimulation) is unique because it involves stimulating the vagus nerve through the skin of the ear, which is different from traditional dyslexia treatments that often focus on educational interventions. This approach is novel as it targets neurological pathways potentially involved in dyslexia, rather than relying solely on behavioral or educational strategies.12345
What is the purpose of this trial?
This is a pilot study to establish feasibility of transcutaneous auricular vagus nerve stimulation (taVNS) for improving letter-learning in adolescents with dyslexia. The main goals of the study are to 1) evaluate whether children in this age range will tolerate low level stimulation over the course of multiple sessions, 2) determine whether low level taVNS improves novel letter learning in dyslexia, and 3) evaluate the effect of low level taVNS on the brain's response to letters. Participants will complete fMRI before training, immediately after training, and a few weeks after training ends. Training will consist of six 30-minute lessons during which participants will learn novel letter-sound relationships while receiving either active or sham taVNS. Researchers will compare stimulation conditions to determine effect of this device on learning and neural plasticity.
Eligibility Criteria
This trial is for adolescents with dyslexia who can read at a certain level (scores above or below 90 on reading measures) and have normal non-verbal IQ. It's not for those with other neurological conditions like autism or epilepsy, nor for those taking medications besides ADHD prescriptions.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive six 30-minute lessons to learn novel letter-sound relationships while receiving either active or sham taVNS
Follow-up
Participants are monitored for safety and effectiveness after treatment, including fMRI assessments
Treatment Details
Interventions
- active taVNS
- sham taVNS
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Florida
Lead Sponsor