50 Participants NeededMy employer runs this trial

Fermented Poi for Gestational Diabetes

Recruiting at 2 trial locations
MK
TO
Overseen ByTomomi Otaki
Age: 18+
Sex: Female
Trial Phase: Academic
Sponsor: University of Hawaii
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This investigator-initiated, non-randomized pilot study evaluates the effect of daily consumption of fermented poi on the maternal microbiome and gestational diabetes risk during pregnancy. Fifty pregnant participants between approximately 12 and 24 weeks of gestation will receive one pound of poi daily for four weeks, accompanied by culturally tailored nutrition education delivered via secure text messaging. Changes in vaginal, oral, and rectal microbiome composition, diet quality, gestational diabetes diagnosis, and pregnancy-related outcomes will be assessed and compared with matched controls derived from an existing cohort. This study aims to inform the feasibility and design of a larger culturally grounded dietary intervention for gestational diabetes prevention.

Who Is on the Research Team?

MK

Marie Kainoa Fialkowski Revilla

Principal Investigator

University of Hawaii

Are You a Good Fit for This Trial?

Inclusion Criteria

Be able to read and write in English
Live on the windward side of O'ahu
I am able to participate in all study activities.
See 4 more

Exclusion Criteria

Not able to read and write in English
Have pre-existing health conditions
Less than 10 weeks pregnant or already in third trimester
See 4 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Dietary Washout

Participants avoid poi and other fermented foods/beverages as specified in the protocol

1 week

Treatment

Participants consume one pound of fermented poi daily for 28 consecutive days, with culturally tailored nutrition education delivered via secure text messaging

4 weeks
Enrollment, baseline, mid-point, end of intervention visits

Follow-up

Participants are monitored for safety and effectiveness after treatment, including assessments in the third trimester

Long-term follow-up in third trimester

What Are the Treatments Tested in This Trial?

Interventions

  • Fermented Poi

How Is the Trial Designed?

1

Treatment groups

Experimental Treatment

Group I: Poi InterventionExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of Hawaii

Lead Sponsor

Trials
122
Recruited
55,200+