TC with nicotine (own brand) for Long QT Syndrome

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Long QT Syndrome+1 MoreTC with nicotine (own brand) - Other
Eligibility
21 - 45
All Sexes
What conditions do you have?
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Study Summary

This trial looked at the effect of smoking an e-cigarette or a tobacco cigarette on heart function.

Eligible Conditions
  • Long QT Syndrome
  • Sudden Cardiac Death

Treatment Effectiveness

Study Objectives

3 Primary · 2 Secondary · Reporting Duration: Change in QT 5 minutes before and 5 minutes after cigarette use

Change in QT 5 minutes before and 5 minutes after cigarette use
QT
Change in QTc 5 minutes before and 5 minutes after cigarette use
QTc
Change in Tpe 5 minutes before and 5 minutes after cigarette use
Tpe
Change in Tpe/QT 5 minutes before and 5 minutes after cigarette use
Tpe/QT
Change in Tpe/QTc 5 minutes before and 5 minutes after cigarette use
Tpe/QTc

Trial Safety

Trial Design

3 Treatment Groups

Chronic EC user
1 of 3
Non-user
1 of 3
Chronic TC smoker
1 of 3

Experimental Treatment

145 Total Participants · 3 Treatment Groups

Primary Treatment: TC with nicotine (own brand) · No Placebo Group · N/A

Chronic EC userExperimental Group · 3 Interventions: EC without nicotine, EC with nicotine, control · Intervention Types: Other, Other, Other
Non-userExperimental Group · 3 Interventions: EC without nicotine, EC with nicotine, control · Intervention Types: Other, Other, Other
Chronic TC smokerExperimental Group · 3 Interventions: TC with nicotine (own brand), research TC with very low level nicotine, control · Intervention Types: Other, Other, Other

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: change in qt 5 minutes before and 5 minutes after cigarette use

Who is running the clinical trial?

University of California, Los AngelesLead Sponsor
1,413 Previous Clinical Trials
6,762,372 Total Patients Enrolled
Tobacco Related Disease Research ProgramOTHER
21 Previous Clinical Trials
2,447 Total Patients Enrolled

Eligibility Criteria

Age 21 - 45 · All Participants · 1 Total Inclusion Criteria

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